Stéphanie Perrinet

The asyptomatic infection by Chlamydia leads to severe complications such as infertility and ectopic pregnancy. We will attempt to understand how chlamydia infection induces either functional or organic infertility in female genital tract and […]

Chlamydia trachomatis  is the most common bacterial cause of sexually transmitted infection and is particularly prevalent in the young population. C. trachomatis  is an obligate intracellular bacterium infecting primarily epithelial cells of the genital […]

Early steps of infection We have observed that chlamydia invasion of a host cell triggers a transient ubiquitination at the entry sites. Deubiquitination follows very rapidly (20 min post infection). We have identified a […]

One of our important discoveries was the identification of a bacterial protein translocated into the host nucleus upon infection (Pennini et al, 2010). This protein, which we called NUE (NUclear Effector), shows histone methyl […]