Dr. Sadri ZNAIDI is a biochemist (B.Sc., M.Sc. from the University of Sherbrooke, Canada) and molecular biologist (Ph.D., from the University of Montreal, Canada), with expertise in yeast genetics and functional genomics. He is currently a RIIP (Institut Pasteur International Network) Affiliate Program Fellow, with affiliations at the Institut Pasteur in Tunis and Paris. His current work focuses on the implementation of systems biology-oriented approaches to identify and characterize components of the biological circuitry involved in the interaction of Candida albicans with the host environment.
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Projects
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Current: RIIP Affiliate Program Fellow, Institut Pasteur in Tunis & Paris
2010 – 2015: Postdoctoral fellow, Institut Pasteur, Paris, France
2004 – 2010: Ph.D., Molecular Biology, University of Montreal, Canada
2002 – 2004: M.Sc., Biochemistry, Université de Sherbrooke, Canada
1999 – 2002: B.Sc., Biochemistry, Université de Sherbrooke, Canada
Publications
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2024A gain-of-function mutation in zinc cluster transcription factor Rob1 Drives Candida albicans adaptive growth in the cystic fibrosis lung environment., PLoS Pathog 2024 Apr; 20(4): e1012154.
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2022Functional Portrait of Irf1 (Orf19.217), a Regulator of Morphogenesis and Iron Homeostasis in Candida albicans., Front Cell Infect Microbiol 2022 ; 12(): 960884.
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2021Ethylzingerone, a Novel Compound with Antifungal Activity., Antimicrob Agents Chemother 2021 03; 65(4): .
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2021High Frequency of Enterocytozoon bieneusi Genotype WL12 Occurrence among Immunocompromised Patients with Intestinal Microsporidiosis., J Fungi (Basel) 2021 Feb; 7(3): .
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2020A conserved regulator controls asexual sporulation in the fungal pathogen Candida albicans., Nat Commun 2020 12; 11(1): 6224.
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2020mSphere of Influence: Decoding Transcriptional Regulatory Networks To Illuminate the Mechanisms of Microbial Pathogenicity., mSphere 2020 01; 5(1): .
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2020Identification and Characterization of Mediators of Fluconazole Tolerance in Candida albicans., Front Microbiol 2020 ; 11(): 591140.
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2019From Genes to Networks: The Regulatory Circuitry Controlling Candida albicans Morphogenesis., Curr Top Microbiol Immunol 2019 ; 422(): 61-99.
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2018A conserved fungal hub protein involved in adhesion and drug resistance in the human pathogen Candida albicans., Cell Surf 2018 Dec; 4(): 10-19.
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2018Systematic gene overexpression in Candida albicans identifies a regulator of early adaptation to the mammalian gut., Cell Microbiol 2018 Nov; 20(11): e12890.
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