Dr. Louis Lambrechts is a Research Director in the Department of Virology at Institut Pasteur in Paris. After graduating from Ecole Normale Supérieure in Paris, he obtained a PhD in Ecology in 2006 for his work on interactions between mosquitoes and malaria parasites at University Pierre & Marie Curie in Paris. During his postdoc, he was supported by a European Marie Curie fellowship to study interactions between mosquitoes and dengue viruses at the University of California in Davis and in the Laboratory of Genetics and Evolution of Infectious Diseases in Montpellier, France. In 2010, he joined the Institut Pasteur in Paris where he became a Permanent Research Scientist of the French Centre National de la Recherche Scientifique (CNRS) in 2011, a Junior Group Leader in 2013, and Unit Head in 2019. In 2018, he was awarded a CNRS Bronze Medal. He is currently involved in several international research programs on dengue and Zika.
Transversal Projects
Projects
CV
Unit Head & Research Director, 2019-present Institut Pasteur, Paris, France
CNRS Bronze Medal, 2018
Junior Group Leader, 2013-2018 Institut Pasteur, Paris, France
CNRS Permanent Research Scientist, 2011-present Institut Pasteur, Paris, France
Postdoctoral Fellow, 2007-11, Arbovirology Institut Pasteur, Paris, France (2010-11); CNRS, Montpellier, France (2009); University of California, Davis, USA (2007-08)
Ph.D., 2006, Ecology University Pierre & Marie Curie, Paris, France
B.S. and M.S., 2002, Biology & Biochemistry Ecole Normale Supérieure, Paris, France
Publications
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2022Mutational analysis of Aedes aegypti Dicer 2 provides insights into the biogenesis of antiviral exogenous small interfering RNAs., PLoS Pathog 2022 Jan; 18(1): e1010202.
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2021Mosquito-bacteria interactions during larval development trigger metabolic changes with carry-over effects on adult fitness., Mol Ecol 2021 Dec; (): .
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2021Potential role of vector-mediated natural selection in dengue virus genotype/lineage replacements in two epidemiologically contrasted settings., Emerg Microbes Infect 2021 Dec; 10(1): 1346-1357.
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2021Did Zika virus attenuation or increased virulence lead to the emergence of congenital Zika syndrome?, J Travel Med 2021 07; 28(5): .
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2021Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains., Nat Commun 2021 02; 12(1): 916.
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2021Insect decline: immediate action is needed., C R Biol 2021 Feb; 343(3): 267-293.
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2020Enhanced Zika virus susceptibility of globally invasive Aedes aegypti populations., Science 2020 11; 370(6519): 991-996.
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2020Experimental adaptation of dengue virus 1 to Aedes albopictus mosquitoes by in vivo selection., Sci Rep 2020 10; 10(1): 18404.
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2020BiteOscope, an open platform to study mosquito biting behavior., Elife 2020 09; 9(): .
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2020Non-retroviral Endogenous Viral Element Limits Cognate Virus Replication in Aedes aegypti Ovaries., Curr Biol 2020 09; 30(18): 3495-3506.e6.
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