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Impact of chromosomal integrons on bacterial life and evolution (Chromintevol)
Céline Loot (PI)
Bacteria exchange and recombine DNA to accelerate their evolution and adapt to new stress. Their evolvability is illustrated by the rapid emergence of multi resistant bacteria after the introduction of antibiotics. The most powerful […]
2022Unbridled Integrons: A Matter of Host Factors., Cells 2022 03; 11(6): .
2021Cassette recruitment in the chromosomal Integron of Vibrio cholerae., Nucleic Acids Res 2021 May; (): .
2020Primary and promiscuous functions coexist during evolutionary innovation through whole protein domain acquisitions., Elife 2020 12; 9(): .
2020Structure-specific DNA recombination sites: Design, validation, and machine learning-based refinement., Sci Adv 2020 Jul; 6(30): eaay2922.
2020Integron Identification in Bacterial Genomes and Cassette Recombination Assays., Methods Mol Biol 2020 ; 2075(): 189-208.
2019Structural heterogeneity of attC integron recombination sites revealed by optical tweezers., Nucleic Acids Res 2019 02; 47(4): 1861-1870.
2017Recoding of synonymous genes to expand evolutionary landscapes requires control of secondary structure affecting translation, Biotechnology & Bioengineering (2018) 115(1):184-191. doi: 10.1002/bit.26450 .
2017Differences in Integron Cassette Excision Dynamics Shape a Trade-Off between Evolvability and Genetic Capacitance, MBio 2017 Mar;8(2).
2016Efficiency of integron cassette insertion in correct orientation is ensured by the interplay of the three unpaired features of attC recombination sites., Nucleic Acids Res. 2016 Aug 5. pii: gkw646. [Epub ahead of print].
2016Adaptation to Global Change: A Transposable Element-Epigenetics Perspective., Trends Ecol Evol 2016 07; 31(7): 514-526.
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