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© Institut Pasteur
Structure de macromolécules : dimère d'aquométhémoglobine de cheval. Dérivé toxique oxydé de l'hémoglobine, représentant 1 à 2% du total.

About

Research Engineer at the platform Biophysics of Macromolecules and their interactions facility, in charge of the spectroscopic line with circular dichroism device, stationary phase and stopped-flow fluorimetry, thermophoresis. The responsibility includes the training of new users, the maintenance and know-how of material, the understanding of the technology allowing the monitoring of short, medium and long term interaction with researchers, beginners or experts who need to complete their studies by biophysical measurements.

Projects

project
Ongoing
8 Members

Biophysical characterization of the translocation process of Bordetella pertussis adenylate cyclase toxin CyaA

Alexandre Chenal (PI)

This project aims to describe the hydrodynamic and thermodynamic properties of the CyaA toxin and the conformational changes it undergoes during its translocation process across the lipid membranes of Bordetella pertussis (secretion) and of […]
project
Ongoing
27 Members

CyaA secretion, folding and translocation across membrane

Alexandre Chenal (PI)

CyaA, a 1706 residue-long protein, is one of the major virulence factors produced by B. pertussis and plays an important role in the early stages of respiratory tract colonization. This toxin uses an original […]

Publications

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