Projects project Ongoing 8 Members Biophysical characterization of the translocation process of Bordetella pertussis adenylate cyclase toxin CyaA Alexandre Chenal (PI) This project aims to describe the hydrodynamic and thermodynamic properties of the CyaA toxin and the conformational changes it undergoes during its translocation process across the lipid membranes of Bordetella pertussis (secretion) and of […] project Ongoing 26 Members CyaA secretion, folding and translocation across membrane Alexandre Chenal (PI) CyaA, a 1706 residue-long protein, is one of the major virulence factors produced by B. pertussis and plays an important role in the early stages of respiratory tract colonization. This toxin uses an original […]
