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© Research
Event

C3BI Seminar: Hierarchical functional genomics to interpret genome variation and dissect complex disease architecture

Scientific Fields
Diseases
Organisms
Applications
Technique
Date
05
Apr 2018
Time
14:00:00
28 Rue du Docteur Roux, Paris, France
Address
Building: Centre François Jacob Room: Auditorium, Rdc
Location
2018-04-05 14:00:00 2018-04-05 15:00:00 Europe/Paris C3BI Seminar: Hierarchical functional genomics to interpret genome variation and dissect complex disease architecture Molecular phenotypes inform us about genetic and environmental effects on cellular and tissue state. The elucidation of the genetic basis of gene expression and other cellular phenotypes is highly informative for the impact of […] 28 Rue du Docteur Roux, Paris, France Maxime Rotival maxime.rotival@pasteur.fr

About

Molecular phenotypes inform us about genetic and environmental effects on cellular and tissue state. The elucidation of the genetic basis of gene expression and other cellular phenotypes is highly informative for the impact of genetic variants in the cell and the subsequent consequences in the organism. In this talk I will discuss recent advances in key areas of the analysis and integration of the genomics of gene expression, chromatin and cellular phenotypes in human populations and multiple tissues from various cohorts including the GTEx consortium and how this assists in the interpretation of regulatory networks and human disease variants. I will also discuss how these recent advances are informing us about the impact of regulatory variation in cancer.

Location

Building: Centre François Jacob
Room: Auditorium, Rdc
Address: 28 Rue du Docteur Roux, Paris, France