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Scientific Fields
Diseases
Organisms
Applications
Technique
Starting Date
03
Apr 2017
Ending Date
07
Apr 2017
Time
09:00:00
25 Rue du Docteur Roux, Paris, France
Address
Building: Lwoff Room: 14-15
Location
2017-04-03 09:00:00 2017-04-07 18:00:00 Europe/Paris Ecole thématique – Bioinformatics of protein­-protein interactions for wet lab scientists The course is intended for PhD students and postdocs working in experimental biology, but scientist of all levels are welcome. Participants will be introduced to a wide variety of popular bioinformatic tools aimed at […] 25 Rue du Docteur Roux, Paris, France Benjamin Bardiaux benjamin.bardiaux@pasteur.fr

About

The course is intended for PhD students and postdocs working in experimental biology, but scientist of all levels are welcome. Participants will be introduced to a wide variety of popular bioinformatic tools aimed at exploring and predicting PPIs. At the end of the course, participants should have an increased ability to:

  • Find and use information on PPIs from diverse databases.
  • Visualise and inspect 3D structure of PPIs and PPI networks.
  • Predict protein modules such as globular domains, unstructured regions and short linear motifs (LMs), from the protein sequence.
  • Portray the characteristics of PPIs between different types of protein modules.
  • Become acquainted with current strategies to target PPIs for drug design.

The course is structured in lectures and practical sessions (hands-on). Practical sessions are optional but highly advised. They will include the following applications:

  • Biological database searches for information on PPI data associated to any protein of interest: UniProt, MINT, ePDB/PDB, among others.
  • Exploration of PPI networks: STRING, STITCH, Cytoscape.
  • Identification of residues responsible for the physical contact between proteins in PPIs using CLUSTALX, JalView, PyMOL, PISA.
  • Prediction of protein interaction modules from protein sequence: using resources such as ELM, IUPRED, Anchor.

The full programme can be found here

Application deadline 15 January 2017

Selected participants will be notified by early February

Apply now!

Speakers

Organizing Committee

Location

Building: Lwoff
Room: 14-15
Address: 25 Rue du Docteur Roux, Paris, France