Adeline Mallet has worked for over 20 years at the Institut Pasteur in the fields of biotechnology and imaging. She holds a PhD from Sorbonne University, Paris, France. Her doctoral research focused on intraflagellar transport pathways in trypanosomes, using various imaging methods, including state-of-the-art electron microscopy techniques, to locate and study the distribution of particles specific to intraflagellar transport. She is currently in charge of the ultrastructural bio-imaging platform at Institut Pasteur France, a position she will take up in 2021. Her work focuses on advanced electron microscopy techniques, including biological sample preparation, protein immunolocalization with colloidal gold particles and three-dimensional FIB-SEM imaging. In addition, she focuses on integrating fluorescence microscopy with nanoscale imaging to study biological phenomena, making significant contributions to fields such as cell biology and host-pathogen interactions. Her work illustrates the intersection between cutting-edge technology and fundamental biological research to develop new methodological workflows.
Click to view graph
Connections
Click to view timeline
Timeline
Past events
Ultrastructural BioImaging User meeting – Daniele Campisi, Manish Singh, Djamel Tahir, Arnaud Duverger, Chie Kodera
Building: François Jacob – Room: Auditorium – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2023-11-29
2023-11-29
Europe/Paris
Adeline Mallet, Ultrastructural BioImaging
Adeline Mallet has worked for over 20 years at the Institut Pasteur in the fields of biotechnology and imaging. She holds a PhD from Sorbonne University, Paris, France. Her doctoral research focused on intraflagellar […]
Institut Pasteur, Rue du Docteur Roux, Paris, France
Amira Software Workshop
Building: CJF –
2022-11-21
2022-11-21
Europe/Paris
Adeline Mallet, Ultrastructural BioImaging
Adeline Mallet has worked for over 20 years at the Institut Pasteur in the fields of biotechnology and imaging. She holds a PhD from Sorbonne University, Paris, France. Her doctoral research focused on intraflagellar […]
2nd FBI CLEM course. Correlative microscopies: theory and applications
Address: 15 Rue Hélène Brion, 75013 Paris, France
2017-05-29
2017-06-02
Europe/Paris
Anastasia Gazi
Viruses were for quite long characterized as the invisible heteronomous agents, (unseen by light microscopy & unable to propagate themselves in the absence of susceptible cells) capable of escaping the bacteriological filters (Rivers, 1932, […]
15 Rue Hélène Brion, 75013 Paris, France
Transversal Projects
Projects
Former Teams
CV
Since 2021 Head of the Ultrastructural BioImaging Platform, Institut Pasteur, Paris, France
2020 : Ph.D. thesis in cell Biology, Institut Pasteur and Parasitology deprtement (PIV) – Trypanosome cell biology Unit, Paris, France (Bastin Philippe group) – Sorbonne Université, France
2013 : Master of science: Biotechnology and bioIformatic, Paris Cité Université, France
Publications
Download-
2025Deciphering Auditory Hyperexcitability in Otogl Mutant Mice Unravels an Auditory Neuropathy Mechanism., Adv Sci (Weinh) 2025 Feb; (): e2410776.
-
2024A free intravesicular C-terminal of otoferlin is essential for synaptic vesicle docking and fusion at auditory inner hair cell ribbon synapses., Prog Neurobiol 2024 Aug; 240(): 102658.
-
2023Three-dimensional images reveal the impact of the endosymbiont Midichloria mitochondrii on the host mitochondria., Nat Commun 2023 Jul; 14(1): 4133.
-
2023Single-cell transcriptomic profiling of the mouse cochlea: An atlas for targeted therapies., Proc Natl Acad Sci U S A 2023 Jun; 120(26): e2221744120.
-
2023Solid-state NMR molecular snapshots of Aspergillus fumigatus cell wall architecture during a conidial morphotype transition., Proc Natl Acad Sci U S A 2023 Feb; 120(6): e2212003120.
-
2022Restriction of intraflagellar transport to some microtubule doublets: An opportunity for cilia diversification?, Bioessays 2022 May; (): e2200031.
-
2021Salmonella enters a dormant state within human epithelial cells for persistent infection., PLoS Pathog 2021 Apr; 17(4): e1009550.
-
2021Ultrastructural Changes of the Mitochondrion During the Life Cycle of Trypanosoma brucei., J Eukaryot Microbiol 2021 Feb; (): e12846.
-
2020Intraflagellar transport during assembly of flagella of different length in Trypanosoma brucei isolated from tsetse flies., J Cell Sci 2020 Sep; 133(18): .
-
2020Timing and original features of flagellum assembly in trypanosomes during development in the tsetse fly., Parasit Vectors 2020 Apr; 13(1): 169.
-
+View full list of publications