Search anything and hit enter
  • Teams
  • Members
  • Projects
  • Events
  • Calls
  • Jobs
  • publications
  • Software
  • Tools
  • Network
  • Equipment

A little guide for advanced search:

  • Tip 1. You can use quotes "" to search for an exact expression.
    Example: "cell division"
  • Tip 2. You can use + symbol to restrict results containing all words.
    Example: +cell +stem
  • Tip 3. You can use + and - symbols to force inclusion or exclusion of specific words.
    Example: +cell -stem
e.g. searching for members in projects tagged cancer
Search for
Count
IN
OUT
Content 1
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Full Professor
  • Graduate Student
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Content 2
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Full Professor
  • Graduate Student
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Search
Go back
Scroll to top
Share
© Research
Publication : Biologie aujourd'hui

[Regulation of intercellular adhesion during epithelial morphogenesis]

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Biologie aujourd'hui - 22 Nov 2012

Levayer R

Link to Pubmed [PMID] – 23171844

Biol Aujourdhui 2012;206(3):219-36

The epithelium is one of the most abundant tissues in metazoans. It is required to generate stable chemical and mechanical barriers between physiological compartments (fluid matrix/external environment). This function is based on multiple intercellular junctions, which insulate and stabilize cell-cell contacts in the tissue. Despite this apparent robustness, epithelia can be extensively remodeled during wound healing, embryogenesis and tumor progression. The capacity to be remodeled while keeping tissue cohesion requires a perfect balance between stability and plasticity of intercellular junctions. The balance is partially regulated by intercellular adhesion, which is mostly based on adherens junctions and the transmembrane protein E-cadherin. The aim of this review is to report the molecular basis of the balance between plasticity and robustness in the epithelium. We will first present the minimal physical framework used to describe epithelial cell shape. We will then describe the main processes involved in intercellular adhesion regulation and their functions during epithelial morphogenesis. Eventually, we will analyze the relationship and the coupling between adhesive forces and cortical tension.

http://www.ncbi.nlm.nih.gov/pubmed/23171844