Timeline

Sylvie Bay

Group Leader

11 Sep 2024

publication

Rocuronium-specific antibodies drive perioperative anaphylaxis but can also function as reversal agents in preclinical models.

22 Jun 2023

event

Single-Domain Antibodies 2023

07 Sep 2021

publication

A Comparative Study on the Efficiency of Two Mycobacterium avium subsp. paratuberculosis (MAP)-Derived Lipopeptides of L3P and L5P as Capture Antigens in an In-House Milk ELISA Test.

01 Jan 2021

publication

Engineering Synthetic Lipopeptide Antigen for Specific Detection of Mycobacterium avium subsp. paratuberculosis Infection.

01 Jan 2021

publication

Interferon-γ Response of Mycobacterium avium subsp. paratuberculosis Infected Goats to Recombinant and Synthetic Mycobacterial Antigens.

01 May 2020

publication

The fully synthetic glycopeptide MAG-Tn3 therapeutic vaccine induces tumor-specific cytotoxic antibodies in breast cancer patients.

20 Dec 2019

publication

Cleaved CD31 as a target for in vivo molecular imaging of inflammation.

10 Jul 2019

publication

An IgG-induced neutrophil activation pathway contributes to human drug-induced anaphylaxis

01 Aug 2017

publication

Selection of similar single domain antibodies from two immune VHH libraries obtained from two alpacas by using different selection methods.

01 Aug 2017

publication

Cell wall peptidolipids of Mycobacterium avium: from genetic prediction to exact structure of a nonribosomal peptide.

21 Jul 2017

publication

Rearranged Biosynthetic Gene Cluster and Synthesis of Hassallidin E in Planktothrix serta PCC 8927

01 Jan 2017

publication

Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate

01 Jan 2017

publication

Chemically-defined camelid antibody bioconjugate for the magnetic resonance imaging of Alzheimer’s disease.

20 Dec 2016

publication

Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate

10 Dec 2016

publication

Camelid single-domain antibodies: A versatile tool for in vivo imaging of extracellular and intracellular brain targets.

01 Mar 2016

publication

The fully synthetic MAG-Tn3 therapeutic vaccine containing the tetanus toxoid-derived TT830-844 universal epitope provides anti-tumor immunity.

01 Jan 2016

publication

Seroreactivity against Specific L5P Antigen from Mycobacterium avium subsp. paratuberculosis in Children at Risk for T1D.

04 Nov 2015

project

Protein conjugates for the diagnosis of Alzheimer’s disease

01 Oct 2015

publication

Interferon gamma response to Mycobacterium avium subsp. paratuberculosis specific lipopentapeptide antigen L5P in cattle.

30 Sep 2015

project

A synthetic glycopeptide for anti-tumor immunotherapy: from design to first use in human

30 Sep 2015

publication

New tools for amyloid plaques detection by MRI: Gadolinium-VHH antibody conjugates

15 Sep 2015

project

Clinical development of cancer vaccines

11 May 2015

team

Chemistry of Biomolecules

19 Mar 2015

project

Use of VHHs for imaging plaques and tangles in Alzheimer’s disease

28 Jun 2013

publication

Mucin-like peptides from Echinococcus granulosus induce antitumor activity

06 Jun 2013

publication

MGL signaling augments TLR2-mediated responses for enhanced IL-10 and TNF-α secretion

02 May 2013

publication

Specific IgG response against Mycobacterium avium paratuberculosis in children and adults with Crohn’s disease

21 Apr 2013

publication

Monoclonal antibodies toward different Tn-amino acid backbones display distinct recognition patterns on human cancer cells. Implications for effective immuno-targeting of cancer

30 May 2012

publication

A Tn antigen binding lectin from Myrsine coriacea displays toxicity in human cancer cell lines

30 Dec 2010

publication

Tn glycosylation of the MUC6 protein modulates its immunogenicity and promotes the induction of Th17-biased T cell responses

18 Aug 2010

publication

Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant

01 Apr 2009

publication

Induction of a melanoma-specific antibody response by a monovalent, but not a divalent, synthetic GM2 neoglycopeptide

17 Oct 2008

publication

The Pta-AckA pathway controlling acetyl phosphate levels and the phosphorylation state of the DegU orphan response regulator both play a role in regulating Listeria monocytogenes motility and chemotaxis

01 Feb 2008

publication

Cinnamic acid, an autoinducer of its own biosynthesis, is processed via Hca enzymes in Photorhabdus luminescens

20 Nov 2007

publication

Lipopentapeptide induces a strong host humoral response and distinguishes Mycobacterium avium subsp. paratuberculosis from M. avium subsp. avium

25 Apr 2007

publication

The combination of electron capture dissociation and fixed charge derivatization increases sequence coverage for O-glycosylated and O-phosphorylated peptides

01 Dec 2006

publication

Carbohydrate antigens: synthesis aspects and immunological applications in cancer

01 Mar 2006

publication

Efficient monitoring of enzymatic conjugation reaction by surface-enhanced laser desorption/ionization time of flight mass spectrometry for process optimization

31 Jan 2006

publication

Enzymatic large-scale synthesis of MUC6-Tn glycoconjugates for antitumor vaccination

01 Sep 2005

publication

Molecular basis of incomplete O-glycan synthesis in MCF-7 breast cancer cells: putative role of MUC6 in Tn antigen expression

29 Jul 2004

publication

Phosphorylcholine-carbohydrate-protein conjugates efficiently induce hapten-specific antibodies which recognize both Streptococcus pneumoniae and Neisseria meningitidis: a potential multitarget vaccine against respiratory infections.

15 Jul 2004

publication

A fully synthetic therapeutic vaccine candidate targeting carcinoma-associated Tn carbohydrate antigen induces tumor-specific antibodies in nonhuman primates

01 Jul 2004

publication

Synthesis and immunological evaluation of an antitumor neoglycopeptide vaccine bearing a novel homoserine Tn antigen

11 Feb 2003

publication

The crystal structure of a plant lectin in complex with the Tn antigen

01 Oct 1993

publication

A little guide for advanced search:

Rocuronium-specific antibodies drive perioperative anaphylaxis but can also function as reversal agents in preclinical models.

Single-Domain Antibodies 2023

A Comparative Study on the Efficiency of Two Mycobacterium avium subsp. paratuberculosis (MAP)-Derived Lipopeptides of L3P and L5P as Capture Antigens in an In-House Milk ELISA Test.

Engineering Synthetic Lipopeptide Antigen for Specific Detection of Mycobacterium avium subsp. paratuberculosis Infection.

Interferon-γ Response of Mycobacterium avium subsp. paratuberculosis Infected Goats to Recombinant and Synthetic Mycobacterial Antigens.

The fully synthetic glycopeptide MAG-Tn3 therapeutic vaccine induces tumor-specific cytotoxic antibodies in breast cancer patients.

Cleaved CD31 as a target for in vivo molecular imaging of inflammation.

An IgG-induced neutrophil activation pathway contributes to human drug-induced anaphylaxis

Selection of similar single domain antibodies from two immune VHH libraries obtained from two alpacas by using different selection methods.

Cell wall peptidolipids of Mycobacterium avium: from genetic prediction to exact structure of a nonribosomal peptide.

Rearranged Biosynthetic Gene Cluster and Synthesis of Hassallidin E in Planktothrix serta PCC 8927

Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate

Chemically-defined camelid antibody bioconjugate for the magnetic resonance imaging of Alzheimer’s disease.

Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate

Camelid single-domain antibodies: A versatile tool for in vivo imaging of extracellular and intracellular brain targets.

The fully synthetic MAG-Tn3 therapeutic vaccine containing the tetanus toxoid-derived TT830-844 universal epitope provides anti-tumor immunity.

Seroreactivity against Specific L5P Antigen from Mycobacterium avium subsp. paratuberculosis in Children at Risk for T1D.

Protein conjugates for the diagnosis of Alzheimer’s disease

Interferon gamma response to Mycobacterium avium subsp. paratuberculosis specific lipopentapeptide antigen L5P in cattle.

A synthetic glycopeptide for anti-tumor immunotherapy: from design to first use in human

New tools for amyloid plaques detection by MRI: Gadolinium-VHH antibody conjugates

Clinical development of cancer vaccines

Chemistry of Biomolecules

Use of VHHs for imaging plaques and tangles in Alzheimer’s disease

Mucin-like peptides from Echinococcus granulosus induce antitumor activity

MGL signaling augments TLR2-mediated responses for enhanced IL-10 and TNF-α secretion

Specific IgG response against Mycobacterium avium paratuberculosis in children and adults with Crohn’s disease

Monoclonal antibodies toward different Tn-amino acid backbones display distinct recognition patterns on human cancer cells. Implications for effective immuno-targeting of cancer

A Tn antigen binding lectin from Myrsine coriacea displays toxicity in human cancer cell lines

Tn glycosylation of the MUC6 protein modulates its immunogenicity and promotes the induction of Th17-biased T cell responses

Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant

Induction of a melanoma-specific antibody response by a monovalent, but not a divalent, synthetic GM2 neoglycopeptide

The Pta-AckA pathway controlling acetyl phosphate levels and the phosphorylation state of the DegU orphan response regulator both play a role in regulating Listeria monocytogenes motility and chemotaxis

Cinnamic acid, an autoinducer of its own biosynthesis, is processed via Hca enzymes in Photorhabdus luminescens

Lipopentapeptide induces a strong host humoral response and distinguishes Mycobacterium avium subsp. paratuberculosis from M. avium subsp. avium

The combination of electron capture dissociation and fixed charge derivatization increases sequence coverage for O-glycosylated and O-phosphorylated peptides

Carbohydrate antigens: synthesis aspects and immunological applications in cancer

Efficient monitoring of enzymatic conjugation reaction by surface-enhanced laser desorption/ionization time of flight mass spectrometry for process optimization

Enzymatic large-scale synthesis of MUC6-Tn glycoconjugates for antitumor vaccination

Molecular basis of incomplete O-glycan synthesis in MCF-7 breast cancer cells: putative role of MUC6 in Tn antigen expression

Phosphorylcholine-carbohydrate-protein conjugates efficiently induce hapten-specific antibodies which recognize both Streptococcus pneumoniae and Neisseria meningitidis: a potential multitarget vaccine against respiratory infections.

A fully synthetic therapeutic vaccine candidate targeting carcinoma-associated Tn carbohydrate antigen induces tumor-specific antibodies in nonhuman primates

Synthesis and immunological evaluation of an antitumor neoglycopeptide vaccine bearing a novel homoserine Tn antigen

The crystal structure of a plant lectin in complex with the Tn antigen

Enzymatic synthesis of some O-beta-D-digalactosyl glycopeptides, using beta-D-galactosidase