Timeline

Stéphanie Pons

Research Engineer

14 Mar 2024

publication

Serum autoantibodies against α7-nicotinic receptors in subgroups of patients with bipolar disorder or schizophrenia: clinical features and link with peripheral inflammation

25 Sep 2023

publication

An original potentiating mechanism revealed by the cryo-EM structures of the human α7 nicotinic receptor in complex with nanobodies.

25 May 2023

publication

Generation of nanobodies acting as silent and positive allosteric modulators of the α7 nicotinic acetylcholine receptor.

31 Mar 2023

publication

Developmental Changes of Human Neural Progenitor Cells Grafted into the Ventricular System and Prefrontal Cortex of Mouse Brain in Utero.

01 Jan 2023

publication

Functional maturation of human iPSC-derived pyramidal neurons in vivo is dependent on proximity with the host tissue.

14 Dec 2021

news

CHRONIC OBSTRUCTIVE PULMONARY DISEASE: A GENETIC MUTATION CONFIRMED AS PREDISPOSING FACTOR

04 Nov 2021

publication

An innate contribution of human nicotinic receptor polymorphisms to COPD-like lesions.

07 Aug 2020

publication

A chimeric mouse model to study human iPSC-derived neurons: the case of a truncating SHANK3 mutation.

01 Mar 2016

publication

Nicotinic receptors in the ventral tegmental area promote uncertainty-seeking.

22 Sep 2015

project

Role of human polymorphisms in nicotinic receptors in lung cancer and COPD

20 Sep 2015

project

Role of the nicotinic receptor in Alzheimer’s disease pathology

11 May 2015

team

Integrative Neurobiology of Cholinergic Systems

01 Aug 2014

publication

Nicotine consumption is regulated by a human polymorphism in dopamine neurons.

05 Mar 2013

publication

Contribution of α7 nicotinic receptor to airway epithelium dysfunction under nicotine exposure.

01 Mar 2013

publication

Co-activation of VTA DA and GABA neurons mediates nicotine reinforcement.

01 Aug 2012

publication

Selective re-expression of β2 nicotinic acetylcholine receptor subunits in the ventral tegmental area of the mouse restores intravenous nicotine self-administration.

01 May 2012

publication

Modulation of the mouse prefrontal cortex activation by neuronal nicotinic receptors during novelty exploration but not by exploration of a familiar environment.

01 Jul 2011

publication

Prefrontal nicotinic receptors control novel social interaction between mice.

12 May 2011

publication

Aversion to nicotine is regulated by the balanced activity of β4 and α5 nicotinic receptor subunits in the medial habenula.

03 May 2011

publication

Distinct contributions of nicotinic acetylcholine receptor subunit alpha4 and subunit alpha6 to the reinforcing effects of nicotine.

01 Mar 2010

publication

A versatile system for the neuronal subtype specific expression of lentiviral vectors.

01 Feb 2010

publication

Effect of the alpha4beta2* nicotinic acetylcholine receptor partial agonist varenicline on dopamine release in beta2 knock-out mice with selective re-expression of the beta2 subunit in the ventral tegmental area.

15 Jun 2006

publication

Hierarchical control of dopamine neuron-firing patterns by nicotinic receptors.

19 May 2005

publication

Nicotine upregulates its own receptors through enhanced intracellular maturation

01 Jun 2004

publication

Nicotine differentially activates inhibitory and excitatory neurons in the dorsal spinal cord

05 Feb 2004

publication

An extracellular protein microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine

15 Oct 2002

publication

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Timeline

Serum autoantibodies against α7-nicotinic receptors in subgroups of patients with bipolar disorder or schizophrenia: clinical features and link with peripheral inflammation

An original potentiating mechanism revealed by the cryo-EM structures of the human α7 nicotinic receptor in complex with nanobodies.

Generation of nanobodies acting as silent and positive allosteric modulators of the α7 nicotinic acetylcholine receptor.

Developmental Changes of Human Neural Progenitor Cells Grafted into the Ventricular System and Prefrontal Cortex of Mouse Brain in Utero.

Functional maturation of human iPSC-derived pyramidal neurons in vivo is dependent on proximity with the host tissue.

CHRONIC OBSTRUCTIVE PULMONARY DISEASE: A GENETIC MUTATION CONFIRMED AS PREDISPOSING FACTOR

An innate contribution of human nicotinic receptor polymorphisms to COPD-like lesions.

A chimeric mouse model to study human iPSC-derived neurons: the case of a truncating SHANK3 mutation.

Nicotinic receptors in the ventral tegmental area promote uncertainty-seeking.

Role of human polymorphisms in nicotinic receptors in lung cancer and COPD

Role of the nicotinic receptor in Alzheimer’s disease pathology

Integrative Neurobiology of Cholinergic Systems

Nicotine consumption is regulated by a human polymorphism in dopamine neurons.

Contribution of α7 nicotinic receptor to airway epithelium dysfunction under nicotine exposure.

Co-activation of VTA DA and GABA neurons mediates nicotine reinforcement.

Selective re-expression of β2 nicotinic acetylcholine receptor subunits in the ventral tegmental area of the mouse restores intravenous nicotine self-administration.

Modulation of the mouse prefrontal cortex activation by neuronal nicotinic receptors during novelty exploration but not by exploration of a familiar environment.

Prefrontal nicotinic receptors control novel social interaction between mice.

Aversion to nicotine is regulated by the balanced activity of β4 and α5 nicotinic receptor subunits in the medial habenula.

Distinct contributions of nicotinic acetylcholine receptor subunit alpha4 and subunit alpha6 to the reinforcing effects of nicotine.

A versatile system for the neuronal subtype specific expression of lentiviral vectors.

Effect of the alpha4beta2* nicotinic acetylcholine receptor partial agonist varenicline on dopamine release in beta2 knock-out mice with selective re-expression of the beta2 subunit in the ventral tegmental area.

Hierarchical control of dopamine neuron-firing patterns by nicotinic receptors.

Nicotine upregulates its own receptors through enhanced intracellular maturation

Nicotine differentially activates inhibitory and excitatory neurons in the dorsal spinal cord

An extracellular protein microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine

Rapsyn escorts the nicotinic acetylcholine receptor along the exocytic pathway via association with lipid rafts