Timeline
Alexandre Pawlik
Research Engineer
01 Apr 2024
publication
A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection.
Read more14 Sep 2022
publication
A lentiviral vector expressing a dendritic cell-targeting multimer induces mucosal anti-mycobacterial CD4+ T-cell immunity.
Read more26 Jul 2022
publication
A lentiviral vector encoding fusion of light invariant chain and mycobacterial antigens induces protective CD4+ T cell immunity.
Read more24 Dec 2021
publication
De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis.
Read more01 Feb 2021
publication
Pathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts.
Read more04 Feb 2020
publication
TbD1 deletion as a driver of the evolutionary success of modern epidemic Mycobacterium tuberculosis lineages
Read more08 Nov 2019
publication
Mycobacterium abscessus virulence traits unraveled by transcriptomic profiling in amoeba and macrophages
Read more11 Jul 2018
publication
Unexpected genomic and phenotypic diversity of Mycobacterium africanum Lineage 5 affects drug resistance, protein secretion and immunogenicity
Read more14 Mar 2017
publication
Recombinant BCG Expressing ESX-1 of Mycobacterium marinum Combines Low Virulence with Cytosolic Immune Signaling and Improved TB Protection
Read more02 Feb 2017
project
Deciphering the virulence factors of Mycobacterium abscessus activated in the presence of environmental amoebae
Read more15 Aug 2016
publication
Key experimental evidence of chromosomal DNA transfer among selected tuberculosis-causing mycobacteria
Read more28 Jul 2016
publication
CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection
Read more28 Apr 2016
publication
A new piperidinol derivative targeting mycolic acid transport in Mycobacterium abscessus
Read more27 Jan 2016
publication
pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence
Read more25 Nov 2015
publication
Revisiting the role of phospholipases C in virulence and the lifecycle of Mycobacterium tuberculosis
Read more05 Nov 2015
publication
The changes in mycolic acid structures caused by hadC mutation have a dramatic effect on the virulence of Mycobacterium tuberculosis
Read more11 May 2015
21 Jul 2014
publication
Evolutionary history of tuberculosis shaped by conserved mutations in the PhoPR virulence regulator
Read more02 Jun 2014
publication
A specific polymorphism in Mycobacterium tuberculosis H37Rv causes differential ESAT-6 expression and identifies WhiB6 as a novel ESX-1 component
Read more06 Jan 2013
publication