Ligne de temps

Alexandre Pawlik
Ingénieur(e) de Recherche
14 Sep 2022
publication

A lentiviral vector expressing a dendritic cell-targeting multimer induces mucosal anti-mycobacterial CD4+ T-cell immunity.

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26 Jul 2022
publication

A lentiviral vector encoding fusion of light invariant chain and mycobacterial antigens induces protective CD4+ T cell immunity.

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24 Dec 2021
publication

De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis.

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01 Feb 2021
publication

Pathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts.

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04 Feb 2020
publication

TbD1 deletion as a driver of the evolutionary success of modern epidemic Mycobacterium tuberculosis lineages

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08 Nov 2019
publication

Mycobacterium abscessus virulence traits unraveled by transcriptomic profiling in amoeba and macrophages

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11 Jul 2018
publication

Unexpected genomic and phenotypic diversity of Mycobacterium africanum Lineage 5 affects drug resistance, protein secretion and immunogenicity

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14 Mar 2017
publication

Recombinant BCG Expressing ESX-1 of Mycobacterium marinum Combines Low Virulence with Cytosolic Immune Signaling and Improved TB Protection

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02 Feb 2017
project

Deciphering the virulence factors of Mycobacterium abscessus activated in the presence of environmental amoebae

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15 Aug 2016
publication

Key experimental evidence of chromosomal DNA transfer among selected tuberculosis-causing mycobacteria

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28 Jul 2016
publication

CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection

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28 Apr 2016
publication

A new piperidinol derivative targeting mycolic acid transport in Mycobacterium abscessus

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27 Jan 2016
publication

pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence

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25 Nov 2015
publication

Revisiting the role of phospholipases C in virulence and the lifecycle of Mycobacterium tuberculosis

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05 Nov 2015
publication

The changes in mycolic acid structures caused by hadC mutation have a dramatic effect on the virulence of Mycobacterium tuberculosis

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11 May 2015
team

Pathogénomique Mycobactérienne Intégrée

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21 Jul 2014
publication

Evolutionary history of tuberculosis shaped by conserved mutations in the PhoPR virulence regulator

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02 Jun 2014
publication

A specific polymorphism in Mycobacterium tuberculosis H37Rv causes differential ESAT-6 expression and identifies WhiB6 as a novel ESX-1 component

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06 Jan 2013
publication

Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis

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