Ligne de temps
Alexandre Pawlik
Ingénieur(e) de Recherche
01 avr. 2024
publication
A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection.
Lire plus14 sept. 2022
publication
A lentiviral vector expressing a dendritic cell-targeting multimer induces mucosal anti-mycobacterial CD4+ T-cell immunity.
Lire plus26 juil. 2022
publication
A lentiviral vector encoding fusion of light invariant chain and mycobacterial antigens induces protective CD4+ T cell immunity.
Lire plus24 déc. 2021
publication
De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis.
Lire plus01 févr. 2021
publication
Pathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts.
Lire plus04 févr. 2020
publication
TbD1 deletion as a driver of the evolutionary success of modern epidemic Mycobacterium tuberculosis lineages
Lire plus08 nov. 2019
publication
Mycobacterium abscessus virulence traits unraveled by transcriptomic profiling in amoeba and macrophages
Lire plus11 juil. 2018
publication
Unexpected genomic and phenotypic diversity of Mycobacterium africanum Lineage 5 affects drug resistance, protein secretion and immunogenicity
Lire plus14 mars 2017
publication
Recombinant BCG Expressing ESX-1 of Mycobacterium marinum Combines Low Virulence with Cytosolic Immune Signaling and Improved TB Protection
Lire plus02 févr. 2017
project
Deciphering the virulence factors of Mycobacterium abscessus activated in the presence of environmental amoebae
Lire plus15 août 2016
publication
Key experimental evidence of chromosomal DNA transfer among selected tuberculosis-causing mycobacteria
Lire plus28 juil. 2016
publication
CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection
Lire plus28 avr. 2016
publication
A new piperidinol derivative targeting mycolic acid transport in Mycobacterium abscessus
Lire plus27 janv. 2016
publication
pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence
Lire plus25 nov. 2015
publication
Revisiting the role of phospholipases C in virulence and the lifecycle of Mycobacterium tuberculosis
Lire plus05 nov. 2015
publication
The changes in mycolic acid structures caused by hadC mutation have a dramatic effect on the virulence of Mycobacterium tuberculosis
Lire plus11 mai 2015
21 juil. 2014
publication
Evolutionary history of tuberculosis shaped by conserved mutations in the PhoPR virulence regulator
Lire plus02 juin 2014
publication
A specific polymorphism in Mycobacterium tuberculosis H37Rv causes differential ESAT-6 expression and identifies WhiB6 as a novel ESX-1 component
Lire plus06 janv. 2013
publication