Non-Flagellar Type III Secretion Systems (NF-T3SS, or injectisomes) are bacterial machineries partially homologous to the bacterial flagellum, which allow direct injection of bacterial effectors from bacterial cytoplasm to eukaryotic cells via a molecular needle (cf. schema above). NF-T3SS are found in animal and plant pathogens, but also in plant and insect symbionts. This website allows to query a dataset of 216 NF-T3SS retrieved from 1385 complete genome sequences. These systems were detected with proteic profiles of NF-T3SS core genes (sctC, sctN, sctJ, sctQ, sctR, sctS, sctT, sctU, sctV), and with an analysis of the genomic context of the hits obtained.
Authors: Sophie Abby, Bertrand Néron, Eduardo Rocha.