Ligne de temps

Eduardo Rocha
Responsable de Structure
17 oct. 2024
news

Intragenomic conflicts with mobile genetic elements drive the evolution of natural transformation in bacteria

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08 oct. 2024
news

Phage-plasmids promote recombination and emergence of phages and plasmids

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08 oct. 2024
news

Hijackers, hitchhikers, or co-drivers? The mysteries of mobilizable genetic elements

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07 oct. 2024
event

Joint seminar Dept Microbiology & Dept Genomes and Genetics “DNA transfer by conjugation in live-cells.”

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01 oct. 2024
publication

Intragenomic conflicts with plasmids and chromosomal mobile genetic elements drive the evolution of natural transformation within species.

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10 juil. 2024
project

Defense systems in integrons: bacterial weapons in a bank (Definbank)

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07 mai 2024
publication

Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans.

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12 mars 2024
publication

Perturbation and resilience of the gut microbiome up to 3 months after β-lactams exposure in healthy volunteers suggest an important role of microbial β-lactamases.

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06 mars 2024
publication

Capsules and their traits shape phage susceptibility and plasmid conjugation efficiency

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20 févr. 2024
publication

Phage-plasmids promote recombination and emergence of phages and plasmids.

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22 janv. 2024
event

GG department seminar: Tai Dagan (University of Kiel, Germany): “Multilevel drift and selection in the evolution of prokaryotic plasmids”; February 1st, 2024 @11.00am; Auditorium F. Jacob

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12 janv. 2024
publication

Cassette recombination dynamics within chromosomal integrons are regulated by toxin-antitoxin systems.

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03 janv. 2024
publication

Integron cassettes integrate into bacterial genomes via widespread non-classical attG sites.

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06 nov. 2023
news

Chance Favors the Prepared Genomes: Horizontal Transfer Shapes the Emergence of Antibiotic Resistance Mutations in Core Genes.

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04 oct. 2023
publication

Chance Favors the Prepared Genomes: Horizontal Transfer Shapes the Emergence of Antibiotic Resistance Mutations in Core Genes.

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03 août 2023
publication

Latent evolution of biofilm formation depends on life-history and genetic background

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30 mai 2023
news

The parasites of parasites: identification and characterization of thousands of bacteriophage satellites across bacteria

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30 mai 2023
software

SatelliteFinder

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06 avr. 2023
news

Highlighted paper: “Competition between lysogenic and sensitive bacteria is determined by the fitness costs of the different emerging phage-resistance strategies” ; Rendueles et al. ; eLife – March 2023

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28 mars 2023
publication

Competition between lysogenic and sensitive bacteria is determined by the fitness costs of the different emerging phage-resistance strategies.

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03 mars 2023
publication

Identification and characterization of thousands of bacteriophage satellites across bacteria.

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29 nov. 2022
publication

Origins of transfer establish networks of functional dependencies for plasmid transfer by conjugation.

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19 oct. 2022
publication

Structural and Genomic Evolution of RRNPPA Systems and Their Pheromone Signaling.

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26 sept. 2022
publication

Phage-Plasmids Spread Antibiotic Resistance Genes through Infection and Lysogenic Conversion.

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13 août 2022
publication

Adaptation to novel spatially-structured environments is driven by the capsule and alters virulence-associated traits.

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02 juin 2022
publication

Evolution of Plasmid Mobility: Origin and Fate of Conjugative and Nonconjugative Plasmids.

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11 mai 2022
publication

Phages and their satellites encode hotspots of antiviral systems.

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17 janv. 2022
publication

To catch a hijacker: abundance, evolution and genetic diversity of P4-like bacteriophage satellites.

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10 nov. 2021
news

Back on: “The Ancient DNA journey: from humans to human pathogens and microbiomes” – 4/11/2021

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21 oct. 2021
news

Back on : the Departemental Retreat 2021 in Pornichet

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06 oct. 2021
event

Ancient DNA journey: from humans to human pathogens and microbiomes

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01 juil. 2021
publication

Interplay between the cell envelope and mobile genetic elements shapes gene flow in populations of the nosocomial pathogen Klebsiella pneumoniae.

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22 avr. 2021
software

CRISPRCasFinder

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22 avr. 2021
software

PanACoTA: A modular tool for massive microbial comparative genomics

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22 avr. 2021
news

Bacteria have numerous phage–plasmids with conserved phage and variable plasmid genes

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18 mars 2021
publication

Bacteria have numerous distinctive groups of phage-plasmids with conserved phage and variable plasmid gene repertoires.

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03 mars 2021
news

Amandine Buffet’s first first author paper on maintenance of the capsule is out!!

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03 mars 2021
publication

Nutrient conditions are primary drivers of bacterial capsule maintenance in Klebsiella

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01 mars 2021
publication

The impact of genetic diversity on gene essentiality within the Escherichia coli species.

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11 févr. 2021
publication

Causes and consequences of bacteriophage diversification via genetic exchanges across lifestyles and bacterial taxa.

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31 juil. 2020
news

Our first experimental paper is out: Prophages in Klebsiella sp. And lots of them!

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30 juil. 2020
publication

Modular prophage interactions driven by capsule serotype select for capsule loss under phage predation

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17 juil. 2020
publication

Pathways for horizontal gene transfer in bacteria revealed by a global map of their plasmids.

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05 juin 2020
publication

A synthesis of bacterial and archaeal phenotypic trait data.

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01 juin 2020
publication

Phylogenetic background and habitat drive the genetic diversification of Escherichia coli.

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08 mai 2020
publication

The major subunit of widespread competence pili exhibits a novel and conserved type IV pilin fold.

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01 mai 2020
publication

The Evolution of Protein Secretion Systems by Co-option and Tinkering of Cellular Machineries.

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29 avr. 2020
publication

Macromolecular crowding links ribosomal protein gene dosage to growth rate in Vibrio cholerae.

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10 févr. 2020
news

Atypical organizations and epistatic interactions of CRISPRs and cas clusters in genomes and their mobile genetic elements

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10 févr. 2020
news

Community diversity and habitat structure shape the repertoire of extracellular proteins in bacteria

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07 févr. 2020
publication

Intracellular Positioning Systems Limit the Entropic Eviction of Secondary Replicons Toward the Nucleoid Edges in Bacterial Cells.

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06 févr. 2020
publication

Community diversity and habitat structure shape the repertoire of extracellular proteins in bacteria.

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01 févr. 2020
publication

Unlinked rRNA genes are widespread among bacteria and archaea.

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24 janv. 2020
publication

Atypical organizations and epistatic interactions of CRISPRs and cas clusters in genomes and their mobile genetic elements

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01 janv. 2020
publication

Identifying Conjugative Plasmids and Integrative Conjugative Elements with CONJscan.

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03 sept. 2019
news

Evolution of the type IV filament superfamily into machines for multiple functions.

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19 juil. 2019
publication

Diversification of the type IV filament superfamily into machines for adhesion, protein secretion, DNA uptake, and motility

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18 juil. 2019
news

Bacteriophages benefit from generalized transduction

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13 mai 2019
publication

A matter of background: DNA repair pathways as a possible cause for the sparse distribution of CRISPR-Cas systems in bacteria

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24 avr. 2019
news

Jean Cury wins the outstanding student paper of the year in MBE

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12 févr. 2019
team

Génétique des génomes

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04 févr. 2019
publication

Ultrafast search of all deposited bacterial and viral genomic data

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07 janv. 2019
news

Genetic exchanges are more frequent in bacteria encoding capsules

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21 déc. 2018
publication

Genetic exchanges are more frequent in bacteria encoding capsules

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02 juil. 2018
publication

CRISPRCasFinder, an update of CRISRFinder, includes a portable version, enhanced performance and integrates search for Cas proteins

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14 juin 2018
publication

Host range and genetic plasticity explain the co-existence of integrative and extrachromosomal mobile genetic elements

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12 juin 2018
news

Parallels between natural and experimental evolution of symbiosis

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11 juin 2018
publication

Parallels between experimental and natural evolution of legume symbionts

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01 juin 2018
publication

Neutral Theory, Microbial Practice: Challenges in Bacterial Population Genetics

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01 janv. 2018
publication

Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement

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12 déc. 2017
publication

Inhibition of NHEJ repair by type II-A CRISPR-Cas systems in bacteria

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11 oct. 2017
news

The treasure troves of bacterial genetic diversity

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10 oct. 2017
publication

The chromosomal organization of horizontal gene transfer in bacteria

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02 oct. 2017
publication

Metagenomic assessment of the interplay between the environment and the genetic diversification of Acinetobacter

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19 sept. 2017
event

Workshop “Recent Computational Advances in Metagenomics (RCAM)” 2017

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18 sept. 2017
publication

Recruitment of a lineage-specific virulence regulatory pathway promotes intracellular infection by a plant pathogen experimentally evolved into a legume symbiont.

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06 sept. 2017
publication

Integrative and conjugative elements and their hosts: composition, distribution and organization

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29 août 2017
publication

A widespread family of polymorphic toxins encoded by temperate phages

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24 juil. 2017
publication

Abundance and co-occurrence of extracellular capsules increase environmental breadth: Implications for the emergence of pathogens

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24 mai 2017
news

Emerging diseases: a highly mutant strain of the Elizabethkingia bacterium caused an outbreak in Wisconsin

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12 avr. 2017
event

“Microbiome evolution and function in social bees” by Nancy MORAN – Genomes & Genetics Departemental seminar co-organized with Microbiology Departement

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10 avr. 2017
publication

Embracing the enemy: the diversification of microbial gene repertoires by phage-mediated horizontal gene transfer

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28 mars 2017
publication

Differences in Integron Cassette Excision Dynamics Shape a Trade-Off between Evolvability and Genetic Capacitance.

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15 mars 2017
event

Seminar “The Evolution of Bacteria Genes and Genomes”

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01 mars 2017
publication

Identification of Protein Secretion Systems in Bacterial Genomes Using MacSyFinder

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01 févr. 2017
tool

CapsuleFinder

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20 déc. 2016
project

ANR SHAPE: Shaping new rhizobia by experimental evolution

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10 oct. 2016
news

A population biology study of Listeria ushers in a new era in listeriosis surveillance

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11 sept. 2016
news

Restriction modification systems as regulators of gene transfer

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27 juil. 2016
publication

Genomic epidemiology and global diversity of the emerging bacterial pathogen Elizabethkingia anophelis

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02 mai 2016
publication

Regulation of genetic flux between bacteria by restriction-modification systems.

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29 avr. 2016
publication

Identification and analysis of integrons and cassette arrays in bacterial genomes.

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25 mars 2016
publication

Genetic and life-history traits associated with the distribution of prophages in bacteria.

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17 mars 2016
publication

Using Sex to Cure the Genome

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16 mars 2016
publication

Identification of protein secretion systems in bacterial genomes

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01 mars 2016
tool

TXSSdb, a database of protein secretion systems

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01 mars 2016
publication

Uncovering Listeria monocytogenes hypervirulence by harnessing its biodiversity.

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01 mars 2016
publication

The impact of selection, gene conversion, and biased sampling on the assessment of microbial demography

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01 févr. 2016
news

Listeria: identification of hypervirulent strains with placental and cerebral tropism

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04 janv. 2016
publication

Coevolution of the Organization and Structure of Prokaryotic Genomes.

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15 nov. 2015
event

C3BI Mini Symposium – New Data, New Questions, New Methods

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10 nov. 2015
software

IntegronFinder

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09 oct. 2015
news

Olaya just got an FRM grant

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08 oct. 2015
tool

TXSScan – models and profiles for protein secretion systems

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06 oct. 2015
news

GEM paper among the all-time top10 of PLoS Genetics

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10 sept. 2015
project

ANR Magisbac : Genesis and Maintenance of Bacterial Secondary Chromosomes

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10 sept. 2015
project

ERC-2011-StG EVOMOBILOME

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05 sept. 2015
tool

Secreton – Non-Flagellar Type III Secretion Systems in sequenced genomes

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05 sept. 2015
tool

ConjDB – a database of conjugative & mobilization systems and T4SS

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05 sept. 2015
software

CONJscan-T4SSscan

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05 sept. 2015
software

Repseek

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05 sept. 2015
software

Swelfe

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05 sept. 2015
software

GrowthPred

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04 sept. 2015
event

2nd Edition of the Workshop Recent computational advances in metagenomics (RCAM’15)

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04 sept. 2015
event

Bi-annual GdR Molecular Bioinformatics (BIM) meeting

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04 sept. 2015
software

MacSyFinder & MacSyView

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04 sept. 2015
software

Repeatoire

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15 juin 2015
project

The imprint of growth

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15 juin 2015
project

DNA repeats and genome dynamics

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11 mai 2015
team

Génomique Évolutive des Microbes

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05 mai 2015
publication

Eco-Evolutionary Dynamics of Episomes among Ecologically Cohesive Bacterial Populations

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25 févr. 2015
publication

Insights on the emergence of Mycobacterium tuberculosis from the analysis of Mycobacterium kansasii

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13 nov. 2014
publication

TLR9 activation is triggered by the excess of stimulatory versus inhibitory motifs present in Trypanosomatidae DNA

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17 oct. 2014
publication

MacSyFinder: a program to mine genomes for molecular systems with an application to CRISPR-Cas systems

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13 oct. 2014
publication

The genomic diversification of the whole Acinetobacter genus: origins, mechanisms, and consequences.

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08 oct. 2014
publication

The chromosomal accommodation and domestication of mobile genetic elements

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02 sept. 2014
publication

Transient hypermutagenesis accelerates the evolution of legume endosymbionts following horizontal gene transfer

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12 août 2014
publication

The interplay of restriction-modification systems with mobile genetic elements and their prokaryotic hosts

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04 août 2014
publication

Pervasive domestication of defective prophages by bacteria

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12 mars 2014
publication

Key components of the eight classes of type IV secretion systems involved in bacterial conjugation or protein secretion

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09 janv. 2014
publication

A PNPase dependent CRISPR System in Listeria

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26 sept. 2013
publication

Manipulating or superseding host recombination functions: a dilemma that shapes phage evolvability

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01 mars 2013
publication

Clinical trial evaluating color change and tooth sensitivity throughout and following in-office bleaching

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01 mars 2013
publication

Evolution. With a little help from prokaryotes

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01 janv. 2013
publication

Natural genome diversity of AI-2 quorum sensing in Escherichia coli: conserved signal production but labile signal reception

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01 janv. 2013
publication

Natural selection for operons depends on genome size

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12 déc. 2012
publication

The adaptation of temperate bacteriophages to their host genomes

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26 nov. 2012
publication

Rapid evolution of the sequences and gene repertoires of secreted proteins in bacteria

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21 nov. 2012
publication

Are diabetes management guidelines applicable in ‘real life’?

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30 oct. 2012
publication

Influence of platform and abutment angulation on peri-implant bone. A three-dimensional finite element stress analysis

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11 oct. 2012
publication

Antibiotic resistance plasmids spread among natural isolates of Escherichia coli in spite of CRISPR elements

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27 sept. 2012
publication

The non-flagellar type III secretion system evolved from the bacterial flagellum and diversified into host-cell adapted systems

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13 sept. 2012
publication

Evolution of conjugation and type IV secretion systems

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24 août 2012
publication

Characterization of novel phages isolated in coagulase-negative staphylococci reveals evolutionary relationships with Staphylococcus aureus phages

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06 juil. 2012
publication

A Single Amino Acid Substitution Changes the Self-Assembly Status of a Type IV Piliation Secretin

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29 févr. 2012
publication

After the bottleneck: Genome-wide diversification of the Mycobacterium tuberculosis complex by mutation, recombination, and natural selection

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02 févr. 2012
publication

Immune subversion and quorum-sensing shape the variation in infectious dose among bacterial pathogens

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30 nov. 2011
publication

Investment in rapid growth shapes the evolutionary rates of essential proteins

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16 sept. 2011
publication

Complete genome sequence of the fish pathogen Flavobacterium branchiophilum

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18 août 2011
publication

The repertoire of ICE in prokaryotes underscores the unity, diversity, and ubiquity of conjugation

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18 mars 2011
publication

CRISPR distribution within the Escherichia coli species is not suggestive of immunity-associated diversifying selection

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24 févr. 2011
publication

Function-specific accelerations in rates of sequence evolution suggest predictable epistatic responses to reduced effective population size

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27 janv. 2011
publication

Horizontal transfer, not duplication, drives the expansion of protein families in prokaryotes

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09 sept. 2010
publication

Mutational patterns cannot explain genome composition: Are there any neutral sites in the genomes of bacteria?

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01 sept. 2010
publication

Mobility of plasmids

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15 juin 2010
publication

The small, slow and specialized CRISPR and anti-CRISPR of Escherichia and Salmonella

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08 avr. 2010
publication

No evidence for elemental-based streamlining of prokaryotic genomes

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24 mars 2010
publication

What traits are carried on mobile genetic elements, and why?

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15 janv. 2010
publication

The systemic imprint of growth and its uses in ecological (meta)genomics

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17 déc. 2009
publication

Genome-wide analysis of DNA repeats in Burkholderia cenocepacia J2315 identifies a novel adhesin-like gene unique to epidemic-associated strains of the ET-12 lineage

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01 oct. 2009
publication

Horizontal gene transfer of the secretome drives the evolution of bacterial cooperation and virulence

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19 sept. 2009
publication

Alternative to homo-oligomerisation: the creation of local symmetry in proteins by internal amplification

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01 mai 2009
publication

Genesis, effects and fates of repeats in prokaryotic genomes

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01 avr. 2009
publication

A novel heuristic for local multiple alignment of interspersed DNA repeats

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23 janv. 2009
publication

Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths

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04 nov. 2008
publication

The temporal dynamics of slightly deleterious mutations in Escherichia coli and Shigella spp

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17 oct. 2008
publication

The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients

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15 oct. 2008
publication

Evolutionary patterns in prokaryotic genomes

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25 juin 2008
publication

An assessment of the impacts of molecular oxygen on the evolution of proteomes

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16 mai 2008
publication

Swelfe: a detector of internal repeats in sequences and structures

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09 mai 2008
publication

Comparison of stress distribution between complete denture and implant-retained overdenture-2D FEA

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26 mars 2008
publication

The impact of the neisserial DNA uptake sequences on genome evolution and stability

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07 janv. 2008
publication

Persistence drives gene clustering in bacterial genomes

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01 janv. 2008
publication

The organization of the bacterial genome

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29 sept. 2007
publication

From GC skews to wavelets: a gentle guide to the analysis of compositional asymmetries in genomic data

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04 sept. 2007
publication

Causes for the intriguing presence of tRNAs in phages

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10 juil. 2007
publication

Reconstructing the ancestor of Mycobacterium leprae: the dynamics of gene loss and genome reduction.

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23 janv. 2007
publication

Causes of insertion sequences abundance in prokaryotic genomes

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15 janv. 2007
publication

Erosion of interaction networks in reduced and degraded genomes

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26 oct. 2006
publication

Similar compositional biases are caused by very different mutational effects

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11 oct. 2006
publication

Repseek, a tool to retrieve approximate repeats from large DNA sequences

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24 août 2006
publication

Protein evolution: causes of trends in amino-acid gain and loss

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01 juil. 2006
publication

Intrastrain heterogeneity of the mgpB gene in Mycoplasma genitalium is extensive in vitro and in vivo and suggests that variation is generated via recombination with repetitive chromosomal sequences

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30 juin 2006
publication

The quest for the universals of protein evolution

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15 mai 2006
publication

An integrative method for accurate comparative genome mapping

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10 mars 2006
publication

Highly variable rates of genome rearrangements between hemiascomycetous yeast lineages

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01 mars 2006
publication

Replication-associated gene dosage effects shape the genomes of fast-growing bacteria but only for transcription and translation genes

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09 nov. 2005
publication

Inference and analysis of the relative stability of bacterial chromosomes

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18 oct. 2005
publication

Comparisons of dN/dS are time dependent for closely related bacterial genomes

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16 sept. 2005
publication

Coping with cold: the genome of the versatile marine Antarctica bacterium Pseudoalteromonas haloplanktis TAC125

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26 août 2005
publication

Comparative and evolutionary analysis of the bacterial homologous recombination systems

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13 juil. 2005
publication

How essential are nonessential genes?

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01 janv. 2005
publication

The unusually large Plasmodium telomerase reverse-transcriptase localizes in a discrete compartment associated with the nucleolus.

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12 oct. 2004
publication

Codon usage bias from tRNA’s point of view: redundancy, specialization, and efficient decoding for translation optimization

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01 oct. 2004
publication

Order and disorder in bacterial genomes

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01 juin 2004
publication

Cytosine methylation is not the major factor inducing CpG dinucleotide deficiency in bacterial genomes

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01 juin 2004
publication

The replication-related organization of bacterial genomes

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15 nov. 2003
publication

Gene essentiality determines chromosome organisation in bacteria

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01 nov. 2003
publication

DNA repeats lead to the accelerated loss of gene order in bacteria

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31 oct. 2003
publication

An analysis of determinants of amino acids substitution rates in bacterial proteins

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01 août 2003
publication

Associations between inverted repeats and the structural evolution of bacterial genomes

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01 août 2003
publication

A strand-specific model for chromosome segregation in bacteria

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01 août 2003
publication

Essentiality, not expressiveness, drives gene-strand bias in bacteria

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12 mai 2003
publication

An appraisal of the potential for illegitimate recombination in bacterial genomes and its consequences: from duplications to genome reduction

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15 oct. 2002
publication

A new family of highly variable proteins in the Chlamydophila pneumoniae genome

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01 sept. 2002
publication

Is there a role for replication fork asymmetry in the distribution of genes in bacterial genomes?

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01 juil. 2002
publication

Origin and fate of repeats in bacteria

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01 juin 2002
publication

Base composition bias might result from competition for metabolic resources

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01 mai 2002
publication

Genomic repeats, genome plasticity and the dynamics of Mycoplasma evolution

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01 mai 2002
publication

Over-representation of repeats in stress response genes: a strategy to increase versatility under stressful conditions?

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01 sept. 2001
publication

Ongoing evolution of strand composition in bacterial genomes

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01 juin 2001
publication

Evolutionary role of restriction/modification systems as revealed by comparative genome analysis

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15 mai 2001
publication

The complete genome sequence of the murine respiratory pathogen Mycoplasma pulmonis

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01 juil. 2000
publication

The DB case: pattern matching evidence is not significant

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30 juin 2000
publication

Sulphur islands in the Escherichia coli genome: markers of the cell’s architecture?

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31 mars 2000
publication

Implication of gene distribution in the bacterial chromosome for the bacterial cell factory

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01 nov. 1999
publication

Functional and evolutionary roles of long repeats in prokaryotes

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01 oct. 1999
publication

Codon usage and lateral gene transfer in Bacillus subtilis

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01 sept. 1999
publication

Analysis of long repeats in bacterial genomes reveals alternative evolutionary mechanisms in Bacillus subtilis and other competent prokaryotes

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01 sept. 1999
publication

Translation in Bacillus subtilis: roles and trends of initiation and termination, insights from a genome analysis

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01 août 1999
publication

Bacterial DNA strand compositional asymmetry: response

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01 avr. 1999
publication

Universal replication biases in bacteria

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15 juin 1998
publication

Oligonucleotide bias in Bacillus subtilis: general trends and taxonomic comparisons

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