Friday 23th September — at 12.00 pm — Salle Monod (Bât.66)
Invited Speaker : Laurence Legeai-Mallet
From Institut Imagine, INSERM U1163
Hosted by Sigolène Meilhac
Abstract : The Fibroblast Growth Factor Receptors (FGFRs) and their family of ligands (FGF) are required throughout embryonic and postnatal skeletal development. Abnormal FGF signaling causes a spectrum of skeletal disorders. Studies of mice engineered with mutations of Fgfr3 found in patients have provided evidence that many of the developmental functions of FGFR3 signaling are conserved between mouse and human. Our work has also uncovered novel aspects of skeletal growth, mandible development, and cranial suture ossification.