Ligne de temps
Philippe Bastin
Responsable de Structure
10 avr. 2024
03 avr. 2024
03 avr. 2024
14 févr. 2024
event
DPT Parasites and Insects Vectors Extraordinary Seminar -Professor Albert DESCOTEAUX “Leishmania remodels host cell organelles”
Lire plus01 août 2023
event
DPT Parasites and Insects Vectors Extraordinary Seminar – Professor Vyacheslav YURCHENKO “Viral and bacterial endobionts of Trypanosomatidae: lessons from the “obscure” species”
Lire plus06 juin 2023
04 avr. 2023
event
DPT Parasites and Insects Vectors Seminar – David PEREZ-MORGA ” Human African Trypanosomiasis evolution and cell death in Trypanosoma brucei brucei – Chapter III”
Lire plus01 janv. 2023
publication
Spatial confinement of Trypanosoma brucei in microfluidic traps provides a new tool to study free swimming parasites.
Lire plus22 nov. 2022
event
DPT Parasites and Insects Vector seminar – Mark CARRINGTON “How do trypanosome receptors for host macromolecules bind ligands and yet avoid the host immune response?”
Lire plus26 oct. 2022
publication
Separate To Operate: the Centriole-Free Inner Core of the Centrosome Regulates the Assembly of the Intranuclear Spindle in Toxoplasma gondii.
Lire plus07 sept. 2022
project
Functional Analysis of novel centrosomal and basal body components of two human parasitic protozoa
Lire plus25 juil. 2022
event
DPT Parasites and insects Vectors Seminar – Maria Francia “Shedding light into the big problem by taking a good look at a tiny organelle; the centrosome and cell division in Toxoplasma gondii”
Lire plus08 juin 2022
31 mai 2022
publication
Restriction of intraflagellar transport to some microtubule doublets: An opportunity for cilia diversification?
Lire plus09 nov. 2021
event
PIV deparment seminar – Isabel RODITI “The sweet and sour sides of cyclic AMP signalling in trypanosomes”
Lire plus27 oct. 2021
event
PIV DPT Seminar – Ariel SILBER “Proline, a “metabolic penknife” for the dangerous lifestyle of Trypanosoma cruzi “
Lire plus20 sept. 2021
publication
The establishment of variant surface glycoprotein monoallelic expression revealed by single-cell RNA-seq of Trypanosoma brucei in the tsetse fly salivary glands.
Lire plus01 juin 2021
publication
Redistribution of FLAgellar Member 8 during the trypanosome life cycle: Consequences for cell fate prediction.
Lire plus23 févr. 2021
publication
Ultrastructural Changes of the Mitochondrion During the Life Cycle of Trypanosoma brucei.
Lire plus04 janv. 2021
19 oct. 2020
23 sept. 2020
publication
Intraflagellar transport during assembly of flagella of different length in Trypanosoma brucei isolated from tsetse flies.
Lire plus22 juin 2020
publication
Dynamic imaging reveals surface exposure of virulent Leishmania amastigotes during pyroptosis of infected macrophages.
Lire plus05 avr. 2020
publication
Timing and original features of flagellum assembly in trypanosomes during development in the tsetse fly.
Lire plus16 janv. 2020
14 janv. 2020
event
MORNing glory: structures and roles of MORN repeat proteins from Trypanosoma, Toxoplasma, and Plasmodium – Brooke Morriswood
Lire plus23 oct. 2019
event
BILBO1 and the fellowship of the ring: Deciphering the composition, assembly and function of the ring of power – Mélanie Bonhivers
Lire plus14 mai 2019
30 avr. 2019
02 avr. 2019
publication
Binding of IFT22 to the intraflagellar transport complex is essential for flagellum assembly
Lire plus25 mars 2019
14 févr. 2019
01 févr. 2019
03 déc. 2018
publication
Bidirectional intraflagellar transport is restricted to two sets of microtubule doublets in the trypanosome flagellum.
Lire plus12 nov. 2018
01 nov. 2018
publication
Biallelic Mutations in LRRC56, Encoding a Protein Associated with Intraflagellar Transport, Cause Mucociliary Clearance and Laterality Defects
Lire plus10 oct. 2018
24 août 2018
25 févr. 2018
14 déc. 2017
16 nov. 2017
publication
Flagellar incorporation of proteins follows at least two different routes in trypanosomes
Lire plus12 mars 2017
publication
Preparation and Observation of Thick Biological Samples by Scanning Transmission Electron Tomography
Lire plus21 déc. 2016
01 août 2016
publication
Intraflagellar transport is required for the maintenance of the trypanosome flagellum composition but not its length
Lire plus21 avr. 2016
14 mars 2016
05 févr. 2016
05 févr. 2016
08 déc. 2015
30 nov. 2015
19 oct. 2015
15 oct. 2015
25 sept. 2015
15 sept. 2015
14 août 2015
14 août 2015
publication
IFT81, encoding an IFT-B core protein, as a very rare cause of a ciliopathy phenotype
Lire plus28 juil. 2015
publication
The Flagellar Arginine Kinase in Trypanosoma brucei Is Important for Infection in Tsetse Flies
Lire plus10 juil. 2015
08 juil. 2015
03 juil. 2015
29 mai 2015
publication
Scanning transmission electron microscopy through-focal tilt-series on biological specimens
Lire plus11 mai 2015
31 mars 2015
publication
The more we know, the more we have to discover: an exciting future for understanding cilia and ciliopathies
Lire plus07 mars 2015
08 janv. 2015
31 déc. 2014
publication
Generation of a nanobody targeting the paraflagellar rod protein of trypanosomes
Lire plus10 nov. 2014
02 juil. 2014
publication
The intraflagellar transport dynein complex of trypanosomes is made of a heterodimer of dynein heavy chains and of light and intermediate chains of distinct functions
Lire plus23 mai 2014
publication
The Leishmania donovani chaperone cyclophilin 40 is essential for intracellular infection independent of its stage-specific phosphorylation status
Lire plus24 avr. 2014
publication
The GTPase IFT27 is involved in both anterograde and retrograde intraflagellar transport
Lire plus16 avr. 2014
publication
Proteomic analysis of intact flagella of procyclic Trypanosoma brucei cells identifies novel flagellar proteins with unique sub-localization and dynamics
Lire plus18 mars 2014
29 nov. 2013
publication
Getting to the heart of intraflagellar transport using Trypanosoma and Chlamydomonas models: the strength is in their differences
Lire plus13 nov. 2013
publication
More than meets the eye: understanding Trypanosoma brucei morphology in the tsetse
Lire plus05 nov. 2013
25 oct. 2013
publication
Flagellar adhesion in Trypanosoma brucei relies on interactions between different skeletal structures in the flagellum and cell body
Lire plus30 août 2013
21 déc. 2012
publication
Apoptotic marker expression in the absence of cell death in staurosporine-treated Leishmania donovani.
Lire plus26 oct. 2012
publication
Trypanosoma brucei FKBP12 differentially controls motility and cytokinesis in procyclic and bloodstream forms
Lire plus19 sept. 2012
04 avr. 2012
publication
A new asymmetric division contributes to the continuous production of infective trypanosomes in the tsetse fly
Lire plus27 mars 2012
publication
NUP-1 Is a large coiled-coil nucleoskeletal protein in trypanosomes with lamin-like functions
Lire plus30 sept. 2011
publication
ALBA proteins are stage regulated during trypanosome development in the tsetse fly and participate in differentiation
Lire plus26 avr. 2011
publication
Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation
Lire plus19 avr. 2011
01 mars 2011
01 mars 2011
18 janv. 2011
publication
Molecular bases of cytoskeleton plasticity during the Trypanosoma brucei parasite cycle
Lire plus29 juin 2010
publication
Cyclosporin A treatment of Leishmania donovani reveals stage-specific functions of cyclophilins in parasite proliferation and viability.
Lire plus25 juin 2010
27 avr. 2010
publication
The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia
Lire plus04 déc. 2009
01 déc. 2009
publication
Loss-of-function mutations in the human ortholog of Chlamydomonas reinhardtii ODA7 disrupt dynein arm assembly and cause primary ciliary dyskinesia
Lire plus23 nov. 2009
publication
Kinesin 9 family members perform separate functions in the trypanosome flagellum
Lire plus24 févr. 2009
publication
A novel function for the atypical small G protein Rab-like 5 in the assembly of the trypanosome flagellum
Lire plus04 févr. 2009
publication
The flagellum-mitogen-activated protein kinase connection in Trypanosomatids: a key sensory role in parasite signalling and development?
Lire plus21 oct. 2008
publication
Flagellum elongation is required for correct structure, orientation and function of the flagellar pocket in Trypanosoma brucei
Lire plus19 déc. 2007
publication
Intraflagellar transport and functional analysis of genes required for flagellum formation in trypanosomes
Lire plus01 août 2007
publication
The Argonaute protein TbAGO1 contributes to large and mini-chromosome segregation and is required for control of RIME retroposons and RHS pseudogene-associated transcripts
Lire plus09 mai 2007
publication
Basal body positioning is controlled by flagellum formation in Trypanosoma brucei
Lire plus01 août 2006
publication
Conserved and specific functions of axoneme components in trypanosome motility
Lire plus09 févr. 2005
01 janv. 2005
12 déc. 2003
publication
TbAGO1, an argonaute protein required for RNA interference, is involved in mitosis and chromosome segregation in Trypanosoma brucei
Lire plus15 oct. 2003
publication
Novel roles for the flagellum in cell morphogenesis and cytokinesis of trypanosomes
Lire plus01 juin 2003
publication
Efficiency and specificity of RNA interference generated by intra- and intermolecular double stranded RNA in Trypanosoma brucei
Lire plus01 janv. 2003
01 mars 2001
01 déc. 2000
01 sept. 2000
publication
Flagellum ontogeny in trypanosomes studied via an inherited and regulated RNA interference system
Lire plus01 déc. 1999
publication
Flagellar morphogenesis: protein targeting and assembly in the paraflagellar rod of trypanosomes
Lire plus01 nov. 1999
publication
Protein transport and flagellum assembly dynamics revealed by analysis of the paralysed trypanosome mutant snl-1
Lire plus01 août 1999
publication
Assembly and function of complex flagellar structures illustrated by the paraflagellar rod of trypanosomes
Lire plus01 févr. 1998
01 déc. 1997
publication
A motility function for the paraflagellar rod of Leishmania parasites revealed by PFR-2 gene knockouts
Lire plus01 août 1996
01 mai 1996
publication
A novel epitope tag system to study protein targeting and organelle biogenesis in Trypanosoma brucei
Lire plus01 févr. 1996
publication
An M(r) 145,000 low-density lipoprotein (LDL)-binding protein is conserved throughout the Kinetoplastida order
Lire plus01 janv. 1995
publication
Activity, pharmacological inhibition and biological regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in Trypanosoma brucei
Lire plus01 févr. 1994
publication
Identification of a specific epitope on the extracellular domain of the LDL-receptor of Trypanosoma brucei brucei
Lire plus01 févr. 1992
publication
Trypanosoma brucei brucei: antigenic stability of its LDL receptor and immunological cross-reactivity with the LDL receptor of the mammalian host
Lire plus15 juil. 1991
publication