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Membres
Iuliana Ene
Responsable de Structure
Responsable
Anciens Membres
2021 Païlin Albie (M2 intern)
Publications
Télécharger-
2021Adaptation to the dietary sugar D-tagatose via genome instability in polyploid Candida albicans cells, G3 Genes|Genomes|Genetics, jkab110.
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2021Comparative genomics of white and opaque cell states supports an epigenetic mechanism of phenotypic switching in Candida albicans, G3 Genes|Genomes|Genetics, Volume 11, Issue 2, February 2021.
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2020Short-term evolution strategies for host adaptation and drug escape in human fungal pathogens, PLoS Pathog 2020 05; 16(5): e1008519.
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2019Mechanisms of genome evolution in Candida albicans, Curr Opin Microbiol 2019 12; 52(): 47-54.
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2019Hemizygosity Enables a Mutational Transition Governing Fungal Virulence and Commensalism, Cell Host Microbe 2019 03; 25(3): 418-431.e6.
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2018Antifungal tolerance is a subpopulation effect distinct from resistance and is associated with persistent candidemia, Nat Commun. 2018 Jun 25;9(1):2470.
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2018Global analysis of mutations driving microevolution of a heterozygous diploid fungal pathogen, Proc Natl Acad Sci U S A 2018 09; 115(37): E8688-E8697.
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2016Phenotypic Profiling Reveals that Candida albicans Opaque Cells Represent a Metabolically Specialized Cell State Compared to Default White Cells, mBio 2016 11; 7(6): .
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2016Systematic Genetic Screen for Transcriptional Regulators of the Candida albicans White-Opaque Switch, Genetics 2016 08; 203(4): 1679-92.
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2015Cell Wall Remodeling Enzymes Modulate Fungal Cell Wall Elasticity and Osmotic Stress Resistance, mBio 2015 Jul; 6(4): e00986.
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Postdoc position
We seek a highly motivated individual with a Ph.D. degree in microbiology, mycology and/or related fields. The candidate should have significant prior research experience and a strong publication record. The applicant should possess excellent verbal and written communication skills. Knowledge of computer programming and/or R Studio is advantageous, but not required. Recent graduates with less than 2 years of postdoctoral training and experience in fungal pathogenesis, genetics, drug responses, transcriptomics, and animal or tissue culture models of infection are preferred. The candidate will be expected to apply for internal and external funding opportunities. The position is available for 3 years and the candidate will be expected to start as soon as possible.
To apply: email iuliana.ene@pasteur.fr
Candidates should include a statement of interest and future goals, a CV, and names of three referees familiar with their scientific abilities.