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Présentation
Services
Booking siteProduction of Custom Micropatterns for Cell Culture
We provide an integrated solution for the design and fabrication of micropatterns. This service based on the local functionalization of cell culture substrates with extracellular matrix components or other proteins.
Organ-on-Chip Technology – Emulate
Organ-on-Chip center The center is equipped with Emulate technology (multiple Zoé and Orbs) Multiple Organ mimics are available (Intestine, Liver, kidney, Lung…). Experiments can be performed in BSL2 and BSL3 (Covid-19) conditions. The center […]
Design and Production of Microfluidic Devices
The Biomaterials and Microfluidics core facility is fully geared for the design, production and testing of microfluidic devices. The team will provide expertise, protocols and equipment to allow users to produce “homemade” chips.
Advanced 3D Cell Culture Systems
We provide a library of 3D cell culture scaffolds with tunable biophysical and biochemical properties.
Équipements
Booking site![](https://research.pasteur.fr/wp-content/uploads/2016/11/research.pasteur.fr_biomaterials-150x150.jpg)
UV/Ozone cleaner • Jelight • UVO Cleaner
This machine is used for sterilizing microfluidic chips, creating micropatterns on glass coverslips or as a source of UV for photopolymerization
![](https://research.pasteur.fr/wp-content/uploads/2016/11/research.pasteur.fr_biomaterials-150x150.jpg)
Rheometer • Malvern • Kinexus Ultra+
This machine is dedicated to the measurement of the mechanical properties of different materials. 20 and 4 mm geometries are available.
![](https://research.pasteur.fr/wp-content/uploads/2016/11/research.pasteur.fr_biomaterials-150x150.jpg)
PDMS • Station • Thinky
This station is equipped with a automated mixer, degassing bottles, a balance a couple of ovens
![](https://research.pasteur.fr/wp-content/uploads/2016/11/research.pasteur.fr_biomaterials-150x150.jpg)
Stylus Profiler • Bruker • DektakXT
A machine for measuring the height and the roughness of microfabricated structures. Range: 0.1 to 500 micron.
![](https://research.pasteur.fr/wp-content/uploads/2016/11/research.pasteur.fr_biomaterials-150x150.jpg)
Computational fluid dynamics simulation • Software • COMSOL Multiphysics
A software dedicated to finite element simulation of the all the physical parameters that can occur in a microfluidic chip (flow, shear stress, diffusion, gradient formation….)
![](https://research.pasteur.fr/wp-content/uploads/2016/11/research.pasteur.fr_biomaterials-150x150.jpg)
2 • Microfluidic syringe pumps • Cetoni • neMESYS
Computer controlled (programmable) syringe pump system dedicated to microfluidic chip perfusion. One controller plus two low pressure modules and a pressure sensor.
![](https://research.pasteur.fr/wp-content/uploads/2016/11/research.pasteur.fr_biomaterials-150x150.jpg)
Inverted microscope for live cell imaging • Zeiss • Axiovert
Inverted microscope for live cell imaging capabilities. The microscope is built for speed in order to reduce the interval between time points when acquiring a timelapse experiment. Standard LED fluorescence is available (Colibri system). […]
![](https://research.pasteur.fr/wp-content/uploads/2016/11/research.pasteur.fr_biomaterials-150x150.jpg)
Oxygen Plasma cleaner • Femto Science • Cute
Oxygen plasma cleaner. Applications: surface activation, PDMS bonding, cleaning. Controllable vacuum, gas injection, power, treatment time.
![](https://research.pasteur.fr/wp-content/uploads/2016/11/research.pasteur.fr_biomaterials-150x150.jpg)
Mask aligner • Süss Microtec • MJB4
Manual mask aligner equipped with a topside microscope and dual objectives. Micrometric screws allow a precise mask-substrate alignment.
Membres
![](https://research.pasteur.fr/wp-content/uploads/2015/05/research_pasteur-samy-gobaa-gobaa-samy-1510-e1634550888980-150x150.jpg)
Samy Gobaa
Responsable de Plateforme
Responsable
Groupes
Group
![](https://research.pasteur.fr/wp-content/uploads/2015/06/research.pasteur.fr_sanso-300x135.jpg)
Groupe Homéostasie Tissulaire: Nathalie Sauvonnet
![](https://research.pasteur.fr/wp-content/uploads/2015/11/research.pasteur.fr_nathaliesauvonnet-150x150.jpg)
Nathalie Sauvonnet
Anciens Membres
2000
2000
Name
Position
2024
2024
Pol Lopez
Undergraduate Student
2024
2024
Agathe Neukelmance
Undergraduate Student
2019
2023
Gizem Altay
Postdoc
2022
2023
Tri Tho Nguyen
Research Engineer
2023
2023
Remy Yim
Undergraduate Student
2021
2023
Martin Frauenlob
Post-doc
2019
2022
Héloïse Mary
Research Engineer
2019
2021
Mélanie Chabaud
Postdoc
2017
2021
Nicolas Minier
PhD Student
2015
2020
Annie Etienne
Assistant
2016
2020
Anette Funfak
Post-doc
2016
2020
Charlotte Bouquerel
Graduate Student
2016
2020
Stefan Rouach
Undergraduate Student
2016
2020
Igor Molybog
Undergraduate Student
2016
2020
Camille Berthault
Undergraduate Student
2016
2020
Yasemin Atiyas
Undergraduate Student
2016
2020
Raphaël Gayet
Visiting Scientist
Projets
Projet Transversal
Financements
Publications
Télécharger-
2025Shigella infection is facilitated by interaction of human enteric α-defensin 5 with colonic epithelial receptor P2Y11., Nat Microbiol 2025 Feb; 10(2): 509-526.
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2024
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2024Modeling memory B cell responses in a lymphoid organ-chip to evaluate mRNA vaccine boosting., J Exp Med 2024 Oct; 221(10): .
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2024Organoids and organ-on-chip technology for investigating host-microorganism interactions., Microbes Infect 2024 Mar; (): 105319.
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2023SCRIB controls apical contractility during epithelial differentiation., J Cell Biol 2023 Dec; 222(12): .
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2023Impact of Green Gold Nanoparticle Coating on Internalization, Trafficking, and Efficiency for Photothermal Therapy of Skin Cancer., ACS Omega 2023 Jan; 8(4): 4092-4105.
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2023In vitro cellular reprogramming to model gonad development and its disorders., Sci Adv 2023 Jan; 9(1): eabn9793.
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20224D live imaging and computational modeling of a functional gut-on-a-chip evaluate how peristalsis facilitates enteric pathogen invasion., Science advances.
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2021Hematopoietic progenitors polarize in contact with bone marrow stromal cells in response to SDF1., J Cell Biol 2021 Nov; 220(11): .
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2021Investigation of RNA metabolism through large-scale genetic interaction profiling in yeast., Nucleic Acids Res 2021 09; 49(15): 8535-8555.
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+Voir la liste complète de publications
Comité utilisateurs
At Biomaterials and Microfluidics core facility we have organized a users committee. The idea is to create a lively community and involve our users in the development of the facility and. Do not hesitate if you have an idea/question.
Contact
Phone: +33 1 44 38 92 75 Email: bmcf@pasteur.fr; samy.gobaa@pasteur.fr Address: 25-28 Rue du Docteur Roux 75015, Paris France