Présentation
Groupes

Groupe Homéostasie Tissulaire: Nathalie Sauvonnet

Services
Booking siteProduction of Custom Micropatterns for Cell Culture
We provide an integrated solution for the design and fabrication of micropatterns. This service based on the local functionalization of cell culture substrates with extracellular matrix components or other proteins.
Organ-on-Chip Technology – Emulate
Organ-on-Chip center The center is equipped with Emulate technology (multiple Zoé and Orbs) Multiple Organ mimics are available (Intestine, Liver, kidney, Lung…). Experiments can be performed in BSL2 and BSL3 (Covid-19) conditions. The center […]
Design and Production of Microfluidic Devices
The Biomaterials and Microfluidics core facility is fully geared for the design, production and testing of microfluidic devices. The team will provide expertise, protocols and equipment to allow users to produce “homemade” chips.
Advanced 3D Cell Culture Systems
We provide a library of 3D cell culture scaffolds with tunable biophysical and biochemical properties.
Équipements
Booking site
Laser photo-ablation station • BMcf • V2
Inverted microscope equipped with a UV pulsed laser and a software that allows carving objects in 3D. designed for phenocopying biological structures in soft hydrogels.
4 • Zoë • CM2 • Emulate
Automated perfusion of S1, R1 and A1 chips. Second generation with improved regulation per channel.
Primo • aléole • 1st gen
Micropatterning, hydrogel polymerization and microfabrication, in a single device. Can be used to create bespoke in vitro cellular microenvironments and to get better cell models for your cell biology experiments or cryo-ET studies.
UV/Ozone cleaner • Jelight • UVO Cleaner
This machine is used for sterilizing microfluidic chips, creating micropatterns on glass coverslips or as a source of UV for photopolymerization
Rheometer • Malvern • Kinexus Ultra+
This machine is dedicated to the measurement of the mechanical properties of different materials. 20 and 4 mm geometries are available.
PDMS • Station • Thinky
This station is equipped with a automated mixer, degassing bottles, a balance a couple of ovens
Stylus Profiler • Bruker • DektakXT
A machine for measuring the height and the roughness of microfabricated structures. Range: 0.1 to 500 micron.
Computational fluid dynamics simulation • Software • COMSOL Multiphysics
A software dedicated to finite element simulation of the all the physical parameters that can occur in a microfluidic chip (flow, shear stress, diffusion, gradient formation….)
2 • Microfluidic syringe pumps • Cetoni • neMESYS
Computer controlled (programmable) syringe pump system dedicated to microfluidic chip perfusion. One controller plus two low pressure modules and a pressure sensor.
Inverted microscope for live cell imaging • Zeiss • Axiovert
Inverted microscope for live cell imaging capabilities. The microscope is built for speed in order to reduce the interval between time points when acquiring a timelapse experiment. Standard LED fluorescence is available (Colibri system). […]
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