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Responsable de Structure
M2 internship: Advanced association mapping in massive multivariate genetic data
Context Public health research on the genetic and environmental causes of common human diseases has fully embraced the era of Big Data. For example, the UK Biobank, the largest human genetic cohort to date, […]
M2 internship: Detection of multivariate genetic effects and their corresponding pathways in cardiometabolic diseases
Context & Objectives Genome-wide association studies (GWAS) – i.e systematic study of the link between millions of genetic variants and a trait in a sample of individuals- have been central to decipher the genetic […]
JASS – Joint Analysis of (GWAS) Summary Statistics
Hugues Aschard (PI)
JASS is a python package that handles the computation of the joint statistics over sets of selected GWAS results, and the interactive exploration of the results through a web interface. The generation of joint […]
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2019Mixed-model admixture mapping identifies smoking-dependent loci of lung function in African Americans, Eur. J. Hum. Genet. 2019 Dec;.
2019Making the Most of Clumping and Thresholding for Polygenic Scores, Am. J. Hum. Genet. 2019 Dec;105(6):1213-1221.
2019Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration, Nat Commun 2019 Nov;10(1):5121.
2019RAISS: robust and accurate imputation from summary statistics, Bioinformatics 2019 Nov;35(22):4837-4839.
2019A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context, Nat Commun 2019 10;10(1):4788.
2019A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals, Microbiome 2019 Sep;7(1):130.
2019Genetic correlations between diabetes and glaucoma: an analysis of continuous and dichotomous phenotypes, Am. J. Ophthalmol. 2019 May;.
2019A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure, Hum. Mol. Genet. 2019 Apr;.
2019Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids, Nat. Genet. 2019 04;51(4):636-648.
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