Most cancer immunotherapies rely on the cytotoxic properties of CD8⁺ T cells, overshadowing the potential activity of CD4⁺ T cells targeting cancer cells. In this new study published in Nature Cancer, the team led […]
Olaya Garcia-Rendueles, who just joined our lab, got a grant from FRM to study the evolution of bacterial capsules. Bacterial capsules are well-known major virulence factors varying greatly within and across species. Yet capsular […]
In our study published in Nature Medicine (Koukouli et al. 2017), we showed that human mutations of nicotinic receptors associated with psychiatric disorders modulate hypofrontality through a hierarchical circuit of inhibitory neurons and chronic nicotine administration […]
Daria Bonazzi, member of the unit ‘Pathogenesis of vascular infections’ led by Guillaume Duménil, received the European Research Council (ERC) Starting grant for her project ‘HOMEPATH – Control of host mechanics by a bacterial […]
Abstract Zika virus (ZIKV) is an emerging virus of the Flaviviridae family, transmitted by Aedes species mosquitoes. The high level of dengue virus (DENV) seroprevalence in areas where ZIKV is circulating and the immunological […]
Thomas Gregor, head of the unit “Physics of Biological Function” has been awarded a European Research Council (ERC) Synergy grant for his project ‘Transcription in 4D: the dynamic interplay between chromatin architecture and gene […]
We feel that the field deserves more visibility in and out of France, and we hope that this event will help establishing new connections between groups with common research interests and approaches. The invited […]
Description of the activity: The past decade has been revolutionary for the field of ancient genomics. The advent of high-throughput sequencing technologies, and the development of better techniques for recovering and sequencing highly degraded […]
Final program: 9 am, Prof. Stewart Cole, Institut Pasteur – Introductory remarks 9.10 am, Christophe d’Enfert, Institut Pasteur – Presentation of the FunHoMic Marie Curie Innovative Training Network 9.20 am, Carol Munro & Alan Walker, […]
Cytokinesis generates a midbody remnant (MBR) that is retained by a daughter cell or captured by distant cells, and can then influence cell fate or promote cell proliferation. Recently, we achieved the purification of […]
Antigenic variation is an immune evasion mechanism used by the malaria parasite Plasmodium falciparum to establish prolonged infection. It prevents parasite clearance by switching the display of variant surface antigens encoded by the 60-member […]
Dr Gregory MOSELEY Department of Microbiology Biomedicine Discovery Institute Monash University, Australia “The P protein axis: a central target to prevent lethal rabies disease?” “Viruses pose one of the grand challenges to human […]
Cocaine addiction is a chronic disorder with a high rate of relapse for which no effective treatment is currently available. Scientists from the Institut Pasteur, the CNRS, Inserm and the Paris Public Hospital Network […]
Dr Philippe Ravaud is a MD-PHD in epidemiology and the director of the Centre of Epidemiology at the Hotel-Dieu (Paris) and of the French Cochrane Centre. For more than 15 years, his primary research has […]
Background and Aims: Hyperammonemia after drug-induced peri-central liver lobule damage, as from overdosing acetaminophen (paracetamol), and can lead to encephalopathy and dead of the patient. Guided by mathematical models, the consensus set of chemical […]
CONFERENCE ORGANIZED BY THE SCIENTIFIC COUNCIL A number of infectious agents, including emerging pathogens and agents responsible for nosocomial infections, reach the blood during infection with severe pathological consequences such as septicemia and meningitis. […]
