We are pleased to announce, The first international conference on CK1 PROTEIN KINASES: “FROM CELL SIGNALING TO THERAPEUTIC TARGETS IN HUMAN DISEASE”.
The event will take place from February 3rd to February 6, 2025, at the Institut Pasteur in Paris, France.
Casein kinase 1 (CK1) is a family of serine/threonine protein kinases that play essential regulatory functions in numerous cellular processes. Defects in CK1 regulation, localization, or mutations within the CK1 coding sequence are associated with critical human diseases such as cancer, neurodegenerative diseases, and sleeping disorders. Therefore, members of the CK1 family have become interesting new drug target molecules, with each paralog having different therapeutic effects. Additionally, there are increasing evidence that intracellular pathogens link CK1 to infectious diseases by manipulating CK1 signalling pathways within host cells.
The conference program aims to encourage the exchange between various scientific communities, promote new lines of research on CK1, and enhance communication, collaboration, and career development for scientists, especially young researchers, from various disciplines. The conference sessions will present and discuss research results from the following areas:
- CK1 in development and regeneration
- Exploring CK1 function in model organisms
- CK1 structure and mechanisms of regulation
- CK1 and circadian clocks
- CK1 in human diseases, part I cancer
- CK1 in human diseases, part II neurodegenerative diseases
- CK1 in human diseases, part III infectious diseases
- Spatial and temporal aspects of signaling
- Targeting CK1 for therapy, part I and II
A round table will also be organised to discuss ways to collaborate on CK1 between different fields.
Prominent scientists in the CK1 community have confirmed their participation as keynote speakers, including:
Opening keynote speaker: David Virshup (Duke-NUS, Singapore), Closing keynote speaker: Volker Dötsch (Goethe university, Germany)
Session keynote speakers: Nagi G Ayad (Georgetown University, USA), Kathy Gould (Vanderbilt university, USA), Nicolas Thomä (The Friedrich Miescher Institute for Biomedical Research, Switzerland), Carrie Partch (University of California Santa Cruz, USA), Yinon Ben-Neriah (The Hebrew university of Jerusalem, Israel), David Strutt (University of Sheffield, United Kingdom), Stefan Knapp (SGC Frankfurt, Germany), Nicolas Robbins (University of Toronto, Canada).
Networking events such as poster sessions and industry exhibitions will also encourage discussions within the CK1 community.
Who should attend?
This event is for all scientists who wish to deepen their knowledge of CK1, as well as those interested in drug target identification, drug discovery for various human diseases.
The organizing committee:
- Gopal Sapkota, University of Dundee, UK
- Carrie Partch, University of California Santa Cruz, USA
- Uwe Knippschild, University of Ulm, Germany
- Vítězslav Bryja, Masaryk University, Czech Republic
- Pascal Marchand, Nantes University, France
- Kathy Gould, Vanderbilt University, USA
- Najma Rachidi, Institut Pasteur, France
The draft programme:
16:00-18:00: Arrival and registration
18:00-18:10: Introduction Najma Rachidi & Uwe Knippschild
18:10-19:00: Opening Keynote lecture: David Virshup (Duke-NUS, Singapore, https://www.duke-nus.edu.sg/cscb/the-team/primary-faculty/Details/detail/david-marc-virshup)
Chair: Najma Rachidi & Uwe Knippschild
19:00-20:15: Session 1 – CK1 in development and regeneration
19:00-19:30 Keynote lecture: Nagi G Ayad (Georgetown university, USA, https://sites.google.com/georgetown.edu/ayadlab/home)
20:15-21:30 Welcome drinks and finger food
09:00-10:55: Session 2 – Exploring CK1 function in model organisms
09:00-09:30 Keynote lecture: Kathy Gould (Vanderbilt University, USA, https://lab.vanderbilt.edu/gould-lab/)
10:30-11:00 Coffee break
11:00-12:45: Session 3: – CK1 molecular structure and regulation
11:00-11:30 Keynote lecture: Nicolas Thomä (The Friedrich Miescher Institute for Biomedical Research, Switzerland, https://www.fmi.ch/research-groups/groupleader.html?group=118)
12:15-12:25 5-10 Turbo talks selected from abstracts (I, 2 min each no question)
12:25-15:30: Lunch on campus
15:30-16:40: Session 4 – CK1 and circadian clocks
15:30-16:00 Keynote lecture: Carrie Partch (University of California Santa Cruz, USA, https://www.partchlab.com/)
16:40-17h00 Coffee break
17:00-18:30: Session 5 – Unexpected roles for CK1 (open to the newest/most exciting data)
17:45-17:55 5-10 Turbo talks selected from abstracts (II)
18:00-20:00 Poster session A and drinks
09:00-10:30: Session 6 – CK1 in human diseases, part I cancer
09:00-09:30 Keynote lecture: Cancer: Yinon Ben-Neriah (The Hebrew university of Jerusalem, Israel, https://medicine.ekmd.huji.ac.il/en/research/yinonb/Pages/default.aspx)
10:30-11:00 Coffee break
11:00-12:15: Session 7 – CK1 in human diseases, part II neurodegenerative diseases
11:00-11:30 Keynote speaker: Alzheimer disease:
12:15-13:00: Session 8 – CK1 in human diseases, part III infectious diseases
13:00-15:30: Lunch on campus
15:30-17:00: Session 9 – Spatial and temporal signalling
15:30-16:00 Keynote lecture: David Strutt (University of Sheffield, UK, https://www.sheffield.ac.uk/biosciences/people/academic-staff/david-strutt)
17:00-17:10 5-10 Turbo talks selected from abstracts (III)
17:10-18:10 Round table, collaborative research on CK1
18:10-20:10 Poster session B and drinks
20:30-23:00 Gala dinner
09:00-10:30: Session 10 – Targeting CK1 for therapy I
09:00-09:30 Keynote lecture: Stefan Knapp (SGC Frankfurt, https://www.thesgc.org/groupprofile/9492)
10:30-11:00 Coffee break
11:00-12:45: Session 11 – Targeting CK1 for therapy II
11:00-11:30 Keynote lecture: Nicole Robbins (University of Toronto, Canada, http://individual.utoronto.ca/cowen/)
12:00-13:00: Closing Keynote lecture: Volker Dötsch (Goethe university, Germany, https://doetsch-lab.de/research/)
13:00-13:15: Closing remarks: Najma Rachidi & Uwe Knippschild
- Registration opening: September 10, 2023
- Abstract submission deadline: November 1, 2024
- Early registration deadline: August 1, 2024
- Registration deadline: November 1, 2024
- Last day for registration cancellation: September 1, 2024 (early registration), December 1, 2024 (later registration).
We look forward to welcoming you to this exciting event. Please visit our website for more information on registration and abstract submission.