• 2024
  Ruggiu M, Guérin MV, Corre B, Bardou M, Alonso R, Russo E, Garcia Z, Feldmann L, Lemaître F, Dusseaux M, Grandjean CL, Bousso P, Anti-PD-1 therapy triggers Tfh cell-dependent IL-4 release to boost CD8 T cell responses in tumor-draining lymph nodes., J Exp Med 2024 Apr; 221(4): .
• 2023
  Boulch M, Cazaux M, Cuffel A, Guerin MV, Garcia Z, Alonso R, Lemaître F, Beer A, Corre B, Menger L, Grandjean CL, Morin F, Thieblemont C, Caillat-Zucman S, Bousso P, Tumor-intrinsic sensitivity to the pro-apoptotic effects of IFN-γ is a major determinant of CD4+ CAR T-cell antitumor activity., Nat Cancer 2023 May; (): .
• 2023
  Corre B, El Janati Elidrissi Y, Duval J, Quilhot M, Lefebvre G, Ecomard S, Lemaître F, Garcia Z, Bohineust A, Russo E, Bousso P, Integration of intermittent calcium signals in T cells revealed by temporally patterned optogenetics., iScience 2023 Feb; 26(2): 106068.
• 2022
  Jarade A, Garcia Z, Marie S, Demera A, Prinz I, Bousso P, Di Santo JP, Serafini N, , Inflammation triggers ILC3 patrolling of the intestinal barrier., Nat Immunol 2022 Aug; (): .
• 2022
  Khazen R, Corre B, Garcia Z, Lemaître F, Bachellier-Bassi S, d'Enfert C, Bousso P, , Spatiotemporal dynamics of calcium signals during neutrophil cluster formation., Proc Natl Acad Sci U S A 2022 Jul; 119(29): e2203855119.
• 2021
  Bardou M, Postat J, Loaec C, Lemaître F, Ronteix G, Garcia Z, Bousso P, , Quorum sensing governs collective dendritic cell activation in vivo., EMBO J 2021 Jun; (): e107176.
• 2021
  Khazen R, Cazaux M, Lemaître F, Corre B, Garcia Z, Bousso P, , Functional heterogeneity of cytotoxic T cells and tumor resistance to cytotoxic hits limit anti-tumor activity in vivo., EMBO J 2021 Apr; (): e106658.
• 2021
  Boulch M, Cazaux M, Loe-Mie Y, Thibaut R, Corre B, Lemaître F, Grandjean CL, Garcia Z, Bousso P, , A cross-talk between CAR T cell subsets and the tumor microenvironment is essential for sustained cytotoxic activity., Sci Immunol 2021 Mar; 6(57): .
• 2021
  Grandjean CL, Garcia Z, Lemaître F, Bréart B, Bousso P, , Imaging the mechanisms of anti-CD20 therapy in vivo uncovers spatiotemporal bottlenecks in antibody-dependent phagocytosis., Sci Adv 2021 Feb; 7(8): .
• 2020
  Ronan Thibaut, Pierre Bost, Idan Milo, Marine Cazaux, Fabrice Lemaître, Zacarias Garcia, Ido Amit, Béatrice Breart, Clémence Cournuot, Benno Schwikowski, Philippe Bousso, Bystander IFN-γ activity promotes widespread and sustained cytokine signaling altering the tumor microenvironment, Nature Cancer 2020 Mar 1(3):302-314.
• 2020
  Thibaut R, Bost P, Milo I, Cazaux M, Lemaître F, Garcia Z, Amit I, Breart B, Cornuot C, Schwikowski B, Bousso P, , Bystander IFN-γ activity promotes widespread and sustained cytokine signaling altering the tumor microenvironment., Nat Cancer 2020 Mar; 1(3): 302-314.
• 2018
  Milo I, Bedora-Faure M, Garcia Z, Thibaut R, Périé L, Shakhar G, Deriano L, Bousso P., The immune system profoundly restricts intratumor genetic heterogeneity, Sci Immunol. 2018 Nov 23;3(29). pii: eaat1435. doi: 10.1126/sciimmunol.aat1435..
• 2018
  Li Y, Masse-Ranson G, Garcia Z, Bruel T, Kök A, Strick-Marchand H, Jouvion G, Serafini N, Lim AI, Dusseaux M, Hieu T, Bourgade F, Toubert A, Finke D, Schwartz O, Bousso P, Mouquet H, Di Santo JP, , A human immune system mouse model with robust lymph node development., Nat Methods 2018 08; 15(8): 623-630.
• 2018
  Bohineust A, Garcia Z, Beuneu H, Lemaître F, Bousso P, Termination of T cell priming relies on a phase of unresponsiveness promoting disengagement from APCs and T cell division, J. Exp. Med. 2018 May;215(5):1481-1492.
• 2016
  Grandjean CL, Montalvao F, Celli S, Michonneau D, Breart B, Garcia Z, Perro M, Freytag O, Gerdes CA, Bousso P, , Intravital imaging reveals improved Kupffer cell-mediated phagocytosis as a mode of action of glycoengineered anti-CD20 antibodies., Sci Rep 2016 10; 6(): 34382.
• 2016
  Michonneau D, Sagoo P, Breart B, Garcia Z, Celli S, Bousso P, The PD-1 Axis Enforces an Anatomical Segregation of CTL Activity that Creates Tumor Niches after Allogeneic Hematopoietic Stem Cell Transplantation, Immunity 2016 Jan;44(1):143-154.
• 2015
  Sagoo P, Garcia Z, Breart B, Lemaître F, Michonneau D, Albert ML, Levy Y, Bousso P, In vivo imaging of inflammasome activation reveals a subcapsular macrophage burst response that mobilizes innate and adaptive immunity, Nat. Med. 2016 Jan;22(1):64-71.
• 2015
  Moreau HD, Lemaître F, Garrod KR, Garcia Z, Lennon-Duménil AM, Bousso P, Signal strength regulates antigen-mediated T-cell deceleration by distinct mechanisms to promote local exploration or arrest, Proc. Natl. Acad. Sci. U.S.A. 2015 Sep;112(39):12151-6.
• 2013
  Montalvao F, Garcia Z, Celli S, Breart B, Deguine J, Van Rooijen N, Bousso P, The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging, J. Clin. Invest. 2013 Dec;123(12):5098-103.
• 2013
  Zeidler U, Bougnoux ME, Lupan A, Helynck O, Doyen A, Garcia Z, Sertour N, Clavaud C, Munier-Lehmann H, Saveanu C, d'Enfert C, Synergy of the antibiotic colistin with echinocandin antifungals in Candida species, J. Antimicrob. Chemother. 2013 Jun;68(6):1285-96.
• 2012
  Garrod KR, Moreau HD, Garcia Z, Lemaître F, Bouvier I, Albert ML, Bousso P, Dissecting T cell contraction in vivo using a genetically encoded reporter of apoptosis, Cell Rep 2012 Nov;2(5):1438-47.
• 2012
  Garcia Z, Lemaître F, van Rooijen N, Albert ML, Levy Y, Schwartz O, Bousso P, Subcapsular sinus macrophages promote NK cell accumulation and activation in response to lymph-borne viral particles, Blood 2012 Dec;120(24):4744-50.
• 2012
  Koltsova EK, Garcia Z, Chodaczek G, Landau M, McArdle S, Scott SR, von Vietinghoff S, Galkina E, Miller YI, Acton ST, Ley K, Dynamic T cell-APC interactions sustain chronic inflammation in atherosclerosis, J. Clin. Invest. 2012 Sep;122(9):3114-26.
• 2012
  Feau S, Garcia Z, Arens R, Yagita H, Borst J, Schoenberger SP, The CD4⁺ T-cell help signal is transmitted from APC to CD8⁺ T-cells via CD27-CD70 interactions, Nat Commun 2012 Jul;3:948.
• 2011
  Nierkens S, den Brok MH, Garcia Z, Togher S, Wagenaars J, Wassink M, Boon L, Ruers TJ, Figdor CG, Schoenberger SP, Adema GJ, Janssen EM, Immune adjuvant efficacy of CpG oligonucleotide in cancer treatment is founded specifically upon TLR9 function in plasmacytoid dendritic cells, Cancer Res. 2011 Oct;71(20):6428-37.
• 2011
  Hennies CM, Reboulet RA, Garcia Z, Nierkens S, Wolkers MC, Janssen EM, Selective expansion of merocytic dendritic cells and CD8DCs confers anti-tumour effect of Fms-like tyrosine kinase 3-ligand treatment in vivo, Clin. Exp. Immunol. 2011 Mar;163(3):381-91.
• 2010
  Beuneu H, Lemaître F, Deguine J, Moreau HD, Bouvier I, Garcia Z, Albert ML, Bousso P, Visualizing the functional diversification of CD8+ T cell responses in lymph nodes, Immunity 2010 Sep;33(3):412-23.
• 2010
  Reboulet RA, Hennies CM, Garcia Z, Nierkens S, Janssen EM, Prolonged antigen storage endows merocytic dendritic cells with enhanced capacity to prime anti-tumor responses in tumor-bearing mice, J. Immunol. 2010 Sep;185(6):3337-47.
• 2009
  Smith TR, Tang X, Maricic I, Garcia Z, Fanchiang S, Kumar V, Dendritic cells use endocytic pathway for cross-priming class Ib MHC-restricted CD8alphaalpha+TCRalphabeta+ T cells with regulatory properties, J. Immunol. 2009 Jun;182(11):6959-68.
• 2008
  Benedict CA, Loewendorf A, Garcia Z, Blazar BR, Janssen EM, Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway, J. Immunol. 2008 Apr;180(7):4836-47.
• 2007
  Mothé BR, Stewart BS, Oseroff C, Bui HH, Stogiera S, Garcia Z, Dow C, Rodriguez-Carreno MP, Kotturi M, Pasquetto V, Botten J, Crotty S, Janssen E, Buchmeier MJ, Sette A, Chronic lymphocytic choriomeningitis virus infection actively down-regulates CD4+ T cell responses directed against a broad range of epitopes, J. Immunol. 2007 Jul;179(2):1058-67.
• 2007
  Garcia Z, Pradelli E, Celli S, Beuneu H, Simon A, Bousso P, Competition for antigen determines the stability of T cell-dendritic cell interactions during clonal expansion, Proc. Natl. Acad. Sci. U.S.A. 2007 Mar;104(11):4553-8.
• 2006
  Beuneu H, Garcia Z, Bousso P, Cutting edge: cognate CD4 help promotes recruitment of antigen-specific CD8 T cells around dendritic cells, J. Immunol. 2006 Aug;177(3):1406-10.
• 2006
  Causevic A, Gentil MV, Delaunay A, El-Soud WA, Garcia Z, Pannetier C, Brignolas F, Hagège D, Maury S, Relationship between DNA methylation and histone acetylation levels, cell redox and cell differentiation states in sugarbeet lines, Planta 2006 Sep;224(4):812-27.
• 2005
  Celli S, Garcia Z, Bousso P, CD4 T cells integrate signals delivered during successive DC encounters in vivo, J. Exp. Med. 2005 Nov;202(9):1271-8.
• 2005
  Bouneaud C, Garcia Z, Kourilsky P, Pannetier C, Lineage relationships, homeostasis, and recall capacities of central- and effector-memory CD8 T cells in vivo, J. Exp. Med. 2005 Feb;201(4):579-90.
• 2003
  Langlade-Demoyen P, Garcia-Pons F, Castiglioni P, Garcia Z, Cardinaud S, Xiong S, Gerloni M, Zanetti M, Role of T cell help and endoplasmic reticulum targeting in protective CTL response against influenza virus, Eur. J. Immunol. 2003 Mar;33(3):720-8.
• 2001
  Ureta-Vidal A, Pique C, Garcia Z, Dehée A, Tortevoye P, Désiré N, Gessain A, Chancerel B, Gout O, Lemonnier FA, Cochet M, Human T cell leukemia virus Type I (HTLV-I) infection induces greater expansions of CD8 T lymphocytes in persons with HTLV-I-associated myelopathy/tropical spastic paraparesis than in asymptomatic carriers, J. Infect. Dis. 2001 Mar;183(6):857-64.
• 1999
  Firat H, Garcia-Pons F, Tourdot S, Pascolo S, Scardino A, Garcia Z, Michel ML, Jack RW, Jung G, Kosmatopoulos K, Mateo L, Suhrbier A, Lemonnier FA, Langlade-Demoyen P, H-2 class I knockout, HLA-A2.1-transgenic mice: a versatile animal model for preclinical evaluation of antitumor immunotherapeutic strategies, Eur. J. Immunol. 1999 10;29(10):3112-21.
• 1999
  Ureta-Vidal A, Garcia Z, Lemonnier FA, Kazanji M, Molecular characterization of cDNAs encoding squirrel monkey (Saïmiri sciureus) CD8 alpha and beta chains, Immunogenetics 1999 Jul;49(7-8):718-21.
• 1998
  Yotnda P, Firat H, Garcia-Pons F, Garcia Z, Gourru G, Vernant JP, Lemonnier FA, Leblond V, Langlade-Demoyen P, Cytotoxic T cell response against the chimeric p210 BCR-ABL protein in patients with chronic myelogenous leukemia, J. Clin. Invest. 1998 May;101(10):2290-6.
• 1995
  Gournier H, Pascolo S, Siegrist CA, Jehan J, Pérarnau B, Garcia Z, Rose T, Neefjes J, Lemonnier FA, Restriction of self-antigen presentation to cytolytic T lymphocytes by mouse peptide pumps, Eur. J. Immunol. 1995 Jul;25(7):2019-26.
• 1993
  Barra C, Gournier H, Garcia Z, Marche PN, Jouvin-Marche E, Briand P, Fillipi P, Lemonnier FA, Abrogation of H-2-restricted CTL responses and efficient recognition of HLA-A3 molecules in DBA/2 HLA/A24 responder mice, J. Immunol. 1993 May;150(9):3681-9.