• 2020
  Bastos PAD, Wheeler R, Boneca IG, , Uptake, recognition and responses to peptidoglycan in the mammalian host., FEMS Microbiol. Rev. 2020 Sep; (): .
• 2020
  Fluckiger A, Daillère R, Sassi M, Sixt BS, Liu P, Loos F, Richard C, Rabu C, Alou MT, Goubet AG, Lemaitre F, Ferrere G, Derosa L, Duong CPM, Messaoudene M, Gagné A, Joubert P, De Sordi L, Debarbieux L, Simon S, Scarlata CM, Ayyoub M, Palermo B, Facciolo F, Boidot R, Wheeler R, Boneca IG, Sztupinszki Z, Papp K, Csabai I, Pasolli E, Segata N, Lopez-Otin C, Szallasi Z, Andre F, Iebba V, Quiniou V, Klatzmann D, Boukhalil J, Khelaifia S, Raoult D, Albiges L, Escudier B, Eggermont A, Mami-Chouaib F, Nistico P, Ghiringhelli F, Routy B, Labarrière N, Cattoir V, Kroemer G, Zitvogel L, , Cross-reactivity between tumor MHC class I-restricted antigens and an enterococcal bacteriophage., Science 2020 08; 369(6506): 936-942.
• 2020
  Bonhomme D, Santecchia I, Vernel-Pauillac F, Caroff M, Germon P, Murray G, Adler B, Boneca IG, Werts C, , Leptospiral LPS escapes mouse TLR4 internalization and TRIF‑associated antimicrobial responses through O antigen and associated lipoproteins., PLoS Pathog. 2020 08; 16(8): e1008639.
• 2020
  Roberti MP, Yonekura S, Duong CPM, Picard M, Ferrere G, Tidjani Alou M, Rauber C, Iebba V, Lehmann CHK, Amon L, Dudziak D, Derosa L, Routy B, Flament C, Richard C, Daillère R, Fluckiger A, Van Seuningen I, Chamaillard M, Vincent A, Kourula S, Opolon P, Ly P, Pizzato E, Becharef S, Paillet J, Klein C, Marliot F, Pietrantonio F, Benoist S, Scoazec JY, Dartigues P, Hollebecque A, Malka D, Pagès F, Galon J, Gomperts Boneca I, Lepage P, Ryffel B, Raoult D, Eggermont A, Vanden Berghe T, Ghiringhelli F, Vandenabeele P, Kroemer G, Zitvogel L, , Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer., Nat. Med. 2020 06; 26(6): 919-931.
• 2020
  Nozeret K, Pernin A, Buddelmeijer N, , Click-Chemistry Based Fluorometric Assay for Apolipoprotein N-acyltransferase from Enzyme Characterization to High-Throughput Screening., J Vis Exp 2020 05; (159): .
• 2020
  Bastos P, Barbosa R, Fernandes M, Alonso I, , A late-onset congenital myasthenic syndrome due to a heterozygous DOK7 mutation., Neuromuscul. Disord. 2020 Apr; 30(4): 331-335.
• 2020
  Williams AH, Wheeler R, Deghmane AE, Santecchia I, Schaub RE, Hicham S, Moya Nilges M, Malosse C, Chamot-Rooke J, Haouz A, Dillard JP, Robins WP, Taha MK, Gomperts Boneca I, , Defective lytic transglycosylase disrupts cell morphogenesis by hindering cell wall de-O-acetylation in Neisseria meningitidis., Elife 2020 Feb; 9(): .
• 2020
  Holzapfel M, Bonhomme D, Cagliero J, Vernel-Pauillac F, Fanton d'Andon M, Bortolussi S, Fiette L, Goarant C, Wunder EA, Picardeau M, Ko AI, Werling D, Matsui M, Boneca IG, Werts C, , Escape of TLR5 Recognition by Leptospira spp.: A Rationale for Atypical Endoflagella., Front Immunol 2020 ; 11(): 2007.
• 2020
  Scornec H, Palud A, Pédron T, Wheeler R, Petitgonnet C, Boneca IG, Cavin JF, Sansonetti PJ, Licandro H, , Study of the cwaRS-ldcA Operon Coding a Two-Component System and a Putative L,D-Carboxypeptidase in Lactobacillus paracasei., Front Microbiol 2020 ; 11(): 156.
• 2019
  Nozeret K, Boucharlat A, Agou F, Buddelmeijer N, A sensitive fluorescence-based assay to monitor enzymatic activity of the essential integral membrane protein Apolipoprotein N-acyltransferase (Lnt), Sci Rep 2019 Nov;9(1):15978.
• 2019
  Scepanovic P, Hodel F, Mondot S, Partula V, Byrd A, Hammer C, Alanio C, Bergstedt J, Patin E, Touvier M, Lantz O, Albert ML, Duffy D, Quintana-Murci L, Fellay J, , , A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals., Microbiome 2019 09; 7(1): 130.
• 2019
  Gasiorowski E, Auger R, Tian X, Hicham S, Ecobichon C, Roure S, Douglass MV, Trent MS, Mengin-Lecreulx D, Touzé T, Boneca IG, HupA, the main undecaprenyl pyrophosphate and phosphatidylglycerol phosphate phosphatase in Helicobacter pylori is essential for colonization of the stomach, PLoS Pathog. 2019 Sep;15(9):e1007972.
• 2019
  Williams AH, Redzej A, Rolhion N, Costa TRD, Rifflet A, Waksman G, Cossart P, The cryo-electron microscopy supramolecular structure of the bacterial stressosome unveils its mechanism of activation, Nat Commun 2019 07;10(1):3005.
• 2019
  Santecchia I, Vernel-Pauillac F, Rasid O, Quintin J, Gomes-Solecki M, Boneca IG, Werts C, Innate immune memory through TLR2 and NOD2 contributes to the control of Leptospira interrogans infection, PLoS Pathog. 2019 May;15(5):e1007811.
• 2019
  Dangkulwanich M, Raetz CRH, Williams AH, Structure guided design of an antibacterial peptide that targets UDP-N-acetylglucosamine acyltransferase, Sci Rep 2019 Mar;9(1):3947.
• 2019
  Dangkulwanich M, Raetz CRH, Williams AH, Structure guided design of an antibacterial peptide that targets UDP-N-acetylglucosamine acyltransferase, Sci Rep 2019 Mar;9(1):3947.
• 2018
  Coullon H, Rifflet A, Wheeler R, Janoir C, Boneca IG, Candela T, Deacetylases required for muramic-δ-lactam production are involved in sporulation, germination, and heat resistance, J. Biol. Chem. 2018 11;293(47):18040-18054.
• 2018
  Dias Bastos PA, Lara Santos L, Pinheiro Vitorino RM, How are the expression patterns of gut antimicrobial peptides modulated by human gastrointestinal diseases? A bridge between infectious, inflammatory, and malignant diseases, J. Pept. Sci. 2018 Mar;24(3).
• 2018
  Williams AH, Wheeler R, Rateau L, Malosse C, Chamot-Rooke J, Haouz A, Taha MK, Boneca IG, , A step-by-step in crystallo guide to bond cleavage and 1,6-anhydro-sugar product synthesis by a peptidoglycan-degrading lytic transglycosylase., J Biol Chem 2018 04; 293(16): 6000-6010.
• 2018
  Vernel-Pauillac F, Werts C, Recent findings related to immune responses against leptospirosis and novel strategies to prevent infection, Microbes Infect. 2018 Oct - Nov;20(9-10):578-588.
• 2018
  Oldenburg R, Mayau V, Prandi J, Arbues A, Astarie-Dequeker C, Guilhot C, Werts C, Winter N, Demangel C, Mycobacterial Phenolic Glycolipids Selectively Disable TRIF-Dependent TLR4 Signaling in Macrophages, Front Immunol 2018;9:2.
• 2018
  Werts C, Interaction of Leptospira with the Innate Immune System, Curr. Top. Microbiol. Immunol. 2018;415:163-187.
• 2017
  Ratet G, Santecchia I, Fanton d'Andon M, Vernel-Pauillac F, Wheeler R, Lenormand P, Fischer F, Lechat P, Haake DA, Picardeau M, Boneca IG, Werts C, LipL21 lipoprotein binding to peptidoglycan enables Leptospira interrogans to escape NOD1 and NOD2 recognition, PLoS Pathog. 2017 12;13(12):e1006725.
• 2017
  Bastos P, Freitas MJ, Gomes A, Vitorino R, Fardilha M, Unravelling the Power of Omics for the Infertile Aging Male, Curr. Pharm. Des. 2017 Nov;23(30):4451-4469.
• 2017
  Bastos P, The Role of Urinary Proteases in Bladder Cancer, Springer Nature Singapore Pte Ltd. 2017.
• 2017
  Contreras-Martel C, Martins A, Ecobichon C, Trindade DM, Matteï PJ, Hicham S, Hardouin P, Ghachi ME, Boneca IG, Dessen A, Molecular architecture of the PBP2-MreC core bacterial cell wall synthesis complex, Nat Commun 2017 10;8(1):776.
• 2017
  Trindade F, Bastos P, Leite-Moreira A, Manadas B, Ferreira R, Soares SF, Daniel-da-Silva AL, Falcão-Pires I, Vitorino R, A fractionation approach applying chelating magnetic nanoparticles to characterize pericardial fluid’s proteome, Arch. Biochem. Biophys. 2017 11;634:1-10.
• 2017
  Belkacem N, Serafini N, Wheeler R, Derrien M, Boucinha L, Couesnon A, Cerf-Bensussan N, Gomperts Boneca I, Di Santo JP, Taha MK, Bourdet-Sicard R, Lactobacillus paracasei feeding improves immune control of influenza infection in mice, PLoS ONE 2017;12(9):e0184976.
• 2017
  Parente MR, Forte E, Falabella M, Boneca IG, Teixeira M, Giuffrè A, Saraiva LM, Nitrosative stress defences of the enterohepatic pathogenic bacterium Helicobacter pullorum, Sci Rep 2017 Aug;7(1):9909.
• 2017
  Potula HH, Richer L, Werts C, Gomes-Solecki M, Pre-treatment with Lactobacillus plantarum prevents severe pathogenesis in mice infected with Leptospira interrogans and may be associated with recruitment of myeloid cells, PLoS Negl Trop Dis 2017 Aug;11(8):e0005870.
• 2017
  Wiktor M, Weichert D, Howe N, Huang CY, Olieric V, Boland C, Bailey J, Vogeley L, Stansfeld PJ, Buddelmeijer N, Wang M, Caffrey M, Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis, Nat Commun 2017 Jul;8:15952.
• 2017
  Ohlsson C, Nigro G, Boneca IG, Bäckhed F, Sansonetti P, Sjögren K, Regulation of bone mass by the gut microbiota is dependent on NOD1 and NOD2 signaling, Cell. Immunol. 2017 Jul;317:55-58.
• 2017
  Dahan J, Levillayer F, Xia T, Nouët Y, Werts C, Fanton d'Andon M, Adib-Conquy M, Cassard-Doulcier AM, Khanna V, Chen J, Tordjmann T, Buendia MA, Jouvion G, Wei Y, LIM-Only Protein FHL2 Is a Negative Regulator of Transforming Growth Factor β1 Expression, Mol. Cell. Biol. 2017 05;37(10).
• 2017
  Bastos P, Ferreira R, Manadas B, Moreira PI, Vitorino R, Insights into the human brain proteome: Disclosing the biological meaning of protein networks in cerebrospinal fluid, Crit Rev Clin Lab Sci 2017 05;54(3):185-204.
• 2017
  Fadouloglou VE, Balomenou S, Aivaliotis M, Kotsifaki D, Arnaouteli S, Tomatsidou A, Efstathiou G, Kountourakis N, Miliara S, Griniezaki M, Tsalafouta A, Pergantis SA, Boneca IG, Glykos NM, Bouriotis V, Kokkinidis M, Unusual α-Carbon Hydroxylation of Proline Promotes Active-Site Maturation, J. Am. Chem. Soc. 2017 Apr;139(15):5330-5337.
• 2017
  Bastos P, Trindade F, Ferreira R, Leite-Moreira A, Falcão-Pires I, Manadas B, Daniel-da-Silva AL, Vitorino R, EDTA-functionalized magnetic nanoparticles: A suitable platform for the analysis of low abundance urinary proteins, Talanta 2017 Aug;170:81-88.
• 2017
  Bastos P, Trindade F, Ferreira R, Casteleiro MA, Stevens R, Klein J, Vitorino R, Unveiling antimicrobial peptide-generating human proteases using PROTEASIX, J Proteomics 2018 01;171:53-62.
• 2017
  Williams AH, Wheeler R, Thiriau C, Haouz A, Taha MK, Boneca IG, , Bulgecin A: The Key to a Broad-Spectrum Inhibitor  That Targets Lytic Transglycosylases., Antibiotics (Basel) 2017 Feb; 6(1): .
• 2017
  Gomes-Solecki M, Santecchia I, Werts C, Animal Models of Leptospirosis: Of Mice and Hamsters, Front Immunol 2017;8:58.
• 2017
  Bastos P, Trindade F, da Costa J, Ferreira R, Vitorino R, Human Antimicrobial Peptides in Bodily Fluids: Current Knowledge and Therapeutic Perspectives in the Postantibiotic Era, Med Res Rev 2018 01;38(1):101-146.
• 2017
  Buddelmeijer N, Identification of Lipoproteins Using Globomycin and Radioactive Palmitate, Methods Mol. Biol. 2017;1615:75-80.
• 2016
  Bastos P, Trindade F, Leite-Moreira A, Falcão-Pires I, Ferreira R, Vitorino R, Methodological approaches and insights on protein aggregation in biological systems, Expert Rev Proteomics 2017 01;14(1):55-68.
• 2016
  Bastos PAD, da Costa JP, Vitorino R, A glimpse into the modulation of post-translational modifications of human-colonizing bacteria, J Proteomics 2017 01;152:254-275.
• 2016
  Daillère R, Vétizou M, Waldschmitt N, Yamazaki T, Isnard C, Poirier-Colame V, Duong CP, Flament C, Lepage P, Roberti MP, Routy B, Jacquelot N, Apetoh L, Becharef S, Rusakiewicz S, Langella P, Sokol H, Kroemer G, Enot D, Roux A, Eggermont A, Tartour E, Johannes L, Woerther PL, Chachaty E, Soria JC, Golden E, Formenti S, Plebanski M, Madondo M, Rosenstiel P, Raoult D, Cattoir V, Boneca IG, Chamaillard M, Zitvogel L, Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects, Immunity 2016 Oct;45(4):931-943.
• 2016
  Herdeiro MT, Bastos PD, Teixeira-Rodrigues A, Roque F, Medicinal Product Regulation: Portugal׳s Framework, Clin Ther 2016 09;38(9):2118-2126.e2.
• 2016
  Urrutia A, Duffy D, Rouilly V, Posseme C, Djebali R, Illanes G, Libri V, Albaud B, Gentien D, Piasecka B, Hasan M, Fontes M, Quintana-Murci L, Albert ML, , Standardized Whole-Blood Transcriptional Profiling Enables the Deconvolution of Complex Induced Immune Responses, Cell Rep 2016 09;16(10):2777-2791.
• 2016
  Pitt JM, Vétizou M, Waldschmitt N, Kroemer G, Chamaillard M, Boneca IG, Zitvogel L, Fine-Tuning Cancer Immunotherapy: Optimizing the Gut Microbiome, Cancer Res. 2016 Aug;76(16):4602-7.
• 2016
  Chaput C, Ecobichon C, Pouradier N, Rousselle JC, Namane A, Boneca IG, Role of the N-Acetylmuramoyl-l-Alanyl Amidase, AmiA, of Helicobacter pylori in Peptidoglycan Metabolism, Daughter Cell Separation, and Virulence, Microb. Drug Resist. 2016 Sep;22(6):477-86.
• 2016
  Boneca IG, The 4(th) Great Wall Symposium, 2015, Microb. Drug Resist. 2016 Sep;22(6):445.
• 2016
  Pitt JM, Vétizou M, Daillère R, Roberti MP, Yamazaki T, Routy B, Lepage P, Boneca IG, Chamaillard M, Kroemer G, Zitvogel L, Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors, Immunity 2016 Jun;44(6):1255-69.
• 2016
  Ficarra FA, Santecchia I, Lagorio SH, Alarcón S, Magni C, Espariz M, Genome mining of lipolytic exoenzymes from Bacillus safensis S9 and Pseudomonas alcaliphila ED1 isolated from a dairy wastewater lagoon, Arch. Microbiol. 2016 Nov;198(9):893-904.
• 2016
  Pitt JM, Vétizou M, Gomperts Boneca I, Lepage P, Chamaillard M, Zitvogel L, Enhancing the clinical coverage and anticancer efficacy of immune checkpoint blockade through manipulation of the gut microbiota, Oncoimmunology 2017;6(1):e1132137.
• 2015
  Vétizou M, Pitt JM, Daillère R, Lepage P, Waldschmitt N, Flament C, Rusakiewicz S, Routy B, Roberti MP, Duong CP, Poirier-Colame V, Roux A, Becharef S, Formenti S, Golden E, Cording S, Eberl G, Schlitzer A, Ginhoux F, Mani S, Yamazaki T, Jacquelot N, Enot DP, Bérard M, Nigou J, Opolon P, Eggermont A, Woerther PL, Chachaty E, Chaput N, Robert C, Mateus C, Kroemer G, Raoult D, Boneca IG, Carbonnel F, Chamaillard M, Zitvogel L, Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota, Science 2015 Nov;350(6264):1079-84.
• 2015
  Clermont D, Gomard M, Hamon S, Bonne I, Fernandez JC, Wheeler R, Malosse C, Chamot-Rooke J, Gribaldo S, Boneca IG, Bizet C, Paenibacillus faecis sp. nov., isolated from human faeces, Int. J. Syst. Evol. Microbiol. 2015 Dec;65(12):4621-6.
• 2015
  Veyrier FJ, Biais N, Morales P, Belkacem N, Guilhen C, Ranjeva S, Sismeiro O, Péhau-Arnaudet G, Rocha EP, Werts C, Taha MK, Boneca IG, , Common Cell Shape Evolution of Two Nasopharyngeal Pathogens., PLoS Genet 2015 Jul; 11(7): e1005338.
• 2015
  Ohnmacht C, Park JH, Cording S, Wing JB, Atarashi K, Obata Y, Gaboriau-Routhiau V, Marques R, Dulauroy S, Fedoseeva M, Busslinger M, Cerf-Bensussan N, Boneca IG, Voehringer D, Hase K, Honda K, Sakaguchi S, Eberl G, The microbiota regulates type 2 immunity through RORγt⁺ T cells, Science 2015 Aug;349(6251):989-93.
• 2014
  Ratet G, Veyrier FJ, Fanton d'Andon M, Kammerscheit X, Nicola MA, Picardeau M, Boneca IG, Werts C, Live imaging of bioluminescent leptospira interrogans in mice reveals renal colonization as a stealth escape from the blood defenses and antibiotics, PLoS Negl Trop Dis 2014 Dec;8(12):e3359.
• 2014
  Williams AH, Veyrier FJ, Bonis M, Michaud Y, Raynal B, Taha MK, White SW, Haouz A, Boneca IG, , Visualization of a substrate-induced productive conformation of the catalytic triad of the Neisseria meningitidis peptidoglycan O-acetylesterase reveals mechanistic conservation in SGNH esterase family members., Acta Crystallogr D Biol Crystallogr 2014 Oct; 70(Pt 10): 2631-9.
• 2014
  Justino MC, Parente MR, Boneca IG, Saraiva LM, FrxA is an S-nitrosoglutathione reductase enzyme that contributes to Helicobacter pylori pathogenicity, FEBS J. 2014 Oct;281(19):4495-505.
• 2014
  Burke TP, Loukitcheva A, Zemansky J, Wheeler R, Boneca IG, Portnoy DA, Listeria monocytogenes is resistant to lysozyme through the regulation, not the acquisition, of cell wall-modifying enzymes, J. Bacteriol. 2014 Nov;196(21):3756-67.
• 2014
  Viaud S, Daillère R, Boneca IG, Lepage P, Pittet MJ, Ghiringhelli F, Trinchieri G, Goldszmid R, Zitvogel L, Harnessing the intestinal microbiome for optimal therapeutic immunomodulation, Cancer Res. 2014 Aug;74(16):4217-21.
• 2014
  Wheeler R, Chevalier G, Eberl G, Gomperts Boneca I, The biology of bacterial peptidoglycans and their impact on host immunity and physiology, Cell. Microbiol. 2014 Jul;16(7):1014-23.
• 2014
  Boneca IG, The Great Wall Symposium, Microb. Drug Resist. 2014 Jun;20(3):189.
• 2014
  Bens M, Vimont S, Ben Mkaddem S, Chassin C, Goujon JM, Balloy V, Chignard M, Werts C, Vandewalle A, Flagellin/TLR5 signalling activates renal collecting duct cells and facilitates invasion and cellular translocation of uropathogenic Escherichia coli, Cell. Microbiol. 2014 Oct;16(10):1503-17.
• 2014
  Viaud S, Daillère R, Boneca IG, Lepage P, Langella P, Chamaillard M, Pittet MJ, Ghiringhelli F, Trinchieri G, Goldszmid R, Zitvogel L, Gut microbiome and anticancer immune response: really hot Sh*t!, Cell Death Differ. 2015 Feb;22(2):199-214.
• 2014
  Candela T, Balomenou S, Aucher W, Bouriotis V, Simore JP, Fouet A, Boneca IG, N-acetylglucosamine deacetylases modulate the anchoring of the gamma-glutamyl capsule to the cell wall of Bacillus anthracis, Microb. Drug Resist. 2014 Jun;20(3):222-30.
• 2014
  Mustapha P, Paris I, Garcia M, Tran CT, Cremniter J, Garnier M, Faure JP, Barthes T, Boneca IG, Morel F, Lecron JC, Burucoa C, Bodet C, Chemokines and antimicrobial peptides have a cag-dependent early response to Helicobacter pylori infection in primary human gastric epithelial cells, Infect. Immun. 2014 Jul;82(7):2881-9.
• 2014
  Rossez Y, Gosset P, Boneca IG, Magalhães A, Ecobichon C, Reis CA, Cieniewski-Bernard C, Joncquel Chevalier Curt M, Léonard R, Maes E, Sperandio B, Slomianny C, Sansonetti PJ, Michalski JC, Robbe-Masselot C, The lacdiNAc-specific adhesin LabA mediates adhesion of Helicobacter pylori to human gastric mucosa, J. Infect. Dis. 2014 Oct;210(8):1286-95.
• 2014
  Irving AT, Mimuro H, Kufer TA, Lo C, Wheeler R, Turner LJ, Thomas BJ, Malosse C, Gantier MP, Casillas LN, Votta BJ, Bertin J, Boneca IG, Sasakawa C, Philpott DJ, Ferrero RL, Kaparakis-Liaskos M, The immune receptor NOD1 and kinase RIP2 interact with bacterial peptidoglycan on early endosomes to promote autophagy and inflammatory signaling, Cell Host Microbe 2014 May;15(5):623-35.
• 2014
  Ait Yahia S, Azzaoui I, Everaere L, Vorng H, Chenivesse C, Marquillies P, Duez C, Delacre M, Grandjean T, Balsamelli J, Fanton d'Andon M, Fan Y, Ple C, Werts C, Boneca IG, Wallaert B, Chamaillard M, Tsicopoulos A, CCL17 production by dendritic cells is required for NOD1-mediated exacerbation of allergic asthma, Am. J. Respir. Crit. Care Med. 2014 Apr;189(8):899-908.
• 2014
  Fanton d'Andon M, Quellard N, Fernandez B, Ratet G, Lacroix-Lamandé S, Vandewalle A, Boneca IG, Goujon JM, Werts C, Leptospira Interrogans induces fibrosis in the mouse kidney through Inos-dependent, TLR- and NLR-independent signaling pathways, PLoS Negl Trop Dis 2014;8(1):e2664.
• 2014
  Vandewalle A, Tourneur E, Bens M, Chassin C, Werts C, Calcineurin/NFAT signaling and innate host defence: a role for NOD1-mediated phagocytic functions, Cell Commun. Signal 2014;12:8.
• 2014
  Viaud S, Daillère R, Yamazaki T, Lepage P, Boneca I, Goldszmid R, Trinchieri G, Zitvogel L, Why should we need the gut microbiota to respond to cancer therapies?, Oncoimmunology 2014 Jan;3(1):e27574.
• 2013
  Veyrier FJ, Ecobichon C, Boneca IG, Draft Genome Sequence of Strain X47-2AL, a Feline Helicobacter pylori Isolate, Genome Announc 2013;1(6).
• 2013
  Viaud S, Saccheri F, Mignot G, Yamazaki T, Daillère R, Hannani D, Enot DP, Pfirschke C, Engblom C, Pittet MJ, Schlitzer A, Ginhoux F, Apetoh L, Chachaty E, Woerther PL, Eberl G, Bérard M, Ecobichon C, Clermont D, Bizet C, Gaboriau-Routhiau V, Cerf-Bensussan N, Opolon P, Yessaad N, Vivier E, Ryffel B, Elson CO, Doré J, Kroemer G, Lepage P, Boneca IG, Ghiringhelli F, Zitvogel L, The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide, Science 2013 Nov;342(6161):971-6.
• 2013
  Hansen JM, Golchin SA, Veyrier FJ, Domenech P, Boneca IG, Azad AK, Rajaram MV, Schlesinger LS, Divangahi M, Reed MB, Behr MA, N-glycolylated peptidoglycan contributes to the immunogenicity but not pathogenicity of Mycobacterium tuberculosis, J. Infect. Dis. 2014 Apr;209(7):1045-54.
• 2013
  Williams AH, Boneca IG, Burrows LL, Bugg TD, The dynamics of peptidoglycan structure and function: conference report on the 3rd Great Wall Symposium, Res. Microbiol. 2014 Jan;165(1):60-7.
• 2013
  Kaplan Zeevi M, Shafir NS, Shaham S, Friedman S, Sigal N, Nir Paz R, Boneca IG, Herskovits AA, Listeria monocytogenes multidrug resistance transporters and cyclic di-AMP, which contribute to type I interferon induction, play a role in cell wall stress, J. Bacteriol. 2013 Dec;195(23):5250-61.
• 2013
  Lantier L, Drouet F, Guesdon W, Mancassola R, Metton C, Lo-Man R, Werts C, Laurent F, Lacroix-Lamandé S, Poly(I:C)-induced protection of neonatal mice against intestinal Cryptosporidium parvum infection requires an additional TLR5 signal provided by the gut flora, J. Infect. Dis. 2014 Feb;209(3):457-67.
• 2013
  Ammam F, Meziane-Cherif D, Mengin-Lecreulx D, Blanot D, Patin D, Boneca IG, Courvalin P, Lambert T, Candela T, The functional vanGCd cluster of Clostridium difficile does not confer vancomycin resistance, Mol. Microbiol. 2013 Aug;89(4):612-25.
• 2013
  Zarantonelli ML, Skoczynska A, Antignac A, El Ghachi M, Deghmane AE, Szatanik M, Mulet C, Werts C, Peduto L, d'Andon MF, Thouron F, Nato F, Lebourhis L, Philpott DJ, Girardin SE, Vives FL, Sansonetti P, Eberl G, Pedron T, Taha MK, Boneca IG, , Penicillin resistance compromises Nod1-dependent proinflammatory activity and virulence fitness of neisseria meningitidis., Cell Host Microbe 2013 Jun; 13(6): 735-45.
• 2013
  Correia M, Michel V, Osório H, El Ghachi M, Bonis M, Boneca IG, De Reuse H, Matos AA, Lenormand P, Seruca R, Figueiredo C, Machado JC, Touati E, Crosstalk between Helicobacter pylori and gastric epithelial cells is impaired by docosahexaenoic acid, PLoS ONE 2013;8(4):e60657.
• 2013
  Correia M, Michel V, Osório H, El Ghachi M, Bonis M, Boneca IG, De Reuse H, Matos AA, Lenormand P, Seruca R, Figueiredo C, Machado JC, Touati E., Crosstalk between Helicobacter pylori and gastric epithelial cells is impaired by docosahexaenoic acid., PLoS One. 2013;8(4):e60657. doi: 10.1371/journal.pone.0060657.
• 2013
  Derbise A, Pierre F, Merchez M, Pradel E, Laouami S, Ricard I, Sirard JC, Fritz J, Lemaître N, Akinbi H, Boneca IG, Sebbane F, Inheritance of the lysozyme inhibitor Ivy was an important evolutionary step by Yersinia pestis to avoid the host innate immune response, J. Infect. Dis. 2013 May;207(10):1535-43.
• 2013
  Veyrier FJ, Williams AH, Mesnage S, Schmitt C, Taha MK, Boneca IG, , De-O-acetylation of peptidoglycan regulates glycan chain extension and affects in vivo survival of Neisseria meningitidis., Mol Microbiol 2013 Mar; 87(5): 1100-12.
• 2013
  Tourneur E, Ben Mkaddem S, Chassin C, Bens M, Goujon JM, Charles N, Pellefigues C, Aloulou M, Hertig A, Monteiro RC, Girardin SE, Philpott DJ, Rondeau E, Elbim C, Werts C, Vandewalle A, Cyclosporine A impairs nucleotide binding oligomerization domain (Nod1)-mediated innate antibacterial renal defenses in mice and human transplant recipients, PLoS Pathog. 2013 Jan;9(1):e1003152.
• 2013
  Balomenou S, Fouet A, Tzanodaskalaki M, Couture-Tosi E, Bouriotis V, Boneca IG, Distinct functions of polysaccharide deacetylases in cell shape, neutral polysaccharide synthesis and virulence of Bacillus anthracis, Mol. Microbiol. 2013 Feb;87(4):867-83.
• 2012
  Zigmond E, Varol C, Farache J, Elmaliah E, Satpathy AT, Friedlander G, Mack M, Shpigel N, Boneca IG, Murphy KM, Shakhar G, Halpern Z, Jung S, Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells, Immunity 2012 Dec;37(6):1076-90.
• 2012
  Roure S, Bonis M, Chaput C, Ecobichon C, Mattox A, Barrière C, Geldmacher N, Guadagnini S, Schmitt C, Prévost MC, Labigne A, Backert S, Ferrero RL, Boneca IG, Peptidoglycan maturation enzymes affect flagellar functionality in bacteria, Mol. Microbiol. 2012 Nov;86(4):845-56.
• 2012
  Bosco-Drayon V, Poidevin M, Boneca IG, Narbonne-Reveau K, Royet J, Charroux B, Peptidoglycan sensing by the receptor PGRP-LE in the Drosophila gut induces immune responses to infectious bacteria and tolerance to microbiota, Cell Host Microbe 2012 Aug;12(2):153-65.
• 2012
  Rossez Y, Maes E, Lefebvre Darroman T, Gosset P, Ecobichon C, Joncquel Chevalier Curt M, Boneca IG, Michalski JC, Robbe-Masselot C, Almost all human gastric mucin O-glycans harbor blood group A, B or H antigens and are potential binding sites for Helicobacter pylori, Glycobiology 2012 Sep;22(9):1193-206.
• 2012
  Bonis M, Williams A, Guadagnini S, Werts C, Boneca IG, The effect of bulgecin A on peptidoglycan metabolism and physiology of Helicobacter pylori, Microb. Drug Resist. 2012 Jun;18(3):230-9.
• 2012
  Justino MC, Ecobichon C, Fernandes AF, Boneca IG, Saraiva LM, Helicobacter pylori has an unprecedented nitric oxide detoxifying system, Antioxid. Redox Signal. 2012 Nov;17(9):1190-200.
• 2012
  Lacroix-Lamandé S, d'Andon MF, Michel E, Ratet G, Philpott DJ, Girardin SE, Boneca IG, Vandewalle A, Werts C, Downregulation of the Na/K-ATPase pump by leptospiral glycolipoprotein activates the NLRP3 inflammasome, J. Immunol. 2012 Mar;188(6):2805-14.
• 2011
  Cullen TW, Giles DK, Wolf LN, Ecobichon C, Boneca IG, Trent MS, Helicobacter pylori versus the host: remodeling of the bacterial outer membrane is required for survival in the gastric mucosa, PLoS Pathog. 2011 Dec;7(12):e1002454.
• 2011
  Wheeler R, Mesnage S, Boneca IG, Hobbs JK, Foster SJ, Super-resolution microscopy reveals cell wall dynamics and peptidoglycan architecture in ovococcal bacteria, Mol. Microbiol. 2011 Dec;82(5):1096-109.
• 2011
  Taherbhoy AM, Tait SW, Kaiser SE, Williams AH, Deng A, Nourse A, Hammel M, Kurinov I, Rock CO, Green DR, Schulman BA, Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway, Mol. Cell 2011 Nov;44(3):451-61.
• 2011
  Hill M, Deghmane AE, Segovia M, Zarantonelli ML, Tilly G, Blancou P, Bériou G, Josien R, Anegon I, Hong E, Ruckly C, Antignac A, El Ghachi M, Boneca IG, Taha MK, Cuturi MC, Penicillin binding proteins as danger signals: meningococcal penicillin binding protein 2 activates dendritic cells through Toll-like receptor 4, PLoS ONE 2011;6(10):e23995.
• 2011
  Marques R, Boneca IG, Expression and functional importance of innate immune receptors by intestinal epithelial cells, Cell. Mol. Life Sci. 2011 Nov;68(22):3661-73.
• 2011
  Veyrier FJ, Boneca IG, Cellier MF, Taha MK, , A novel metal transporter mediating manganese export (MntX) regulates the Mn to Fe intracellular ratio and Neisseria meningitidis virulence., PLoS Pathog 2011 Sep; 7(9): e1002261.
• 2011
  El Ghachi M, Matteï PJ, Ecobichon C, Martins A, Hoos S, Schmitt C, Colland F, Ebel C, Prévost MC, Gabel F, England P, Dessen A, Boneca IG, Characterization of the elongasome core PBP2 : MreC complex of Helicobacter pylori, Mol. Microbiol. 2011 Oct;82(1):68-86.
• 2011
  Aubry C, Goulard C, Nahori MA, Cayet N, Decalf J, Sachse M, Boneca IG, Cossart P, Dussurget O, OatA, a peptidoglycan O-acetyltransferase involved in Listeria monocytogenes immune escape, is critical for virulence, J. Infect. Dis. 2011 Sep;204(5):731-40.
• 2011
  Sarfo FS, Le Chevalier F, Aka N, Phillips RO, Amoako Y, Boneca IG, Lenormand P, Dosso M, Wansbrough-Jones M, Veyron-Churlet R, Guenin-Macé L, Demangel C, Mycolactone diffuses into the peripheral blood of Buruli ulcer patients–implications for diagnosis and disease monitoring, PLoS Negl Trop Dis 2011 Jul;5(7):e1237.
• 2011
  Werts C, Rubino S, Ling A, Girardin SE, Philpott DJ, Nod-like receptors in intestinal homeostasis, inflammation, and cancer, J. Leukoc. Biol. 2011 Sep;90(3):471-82.
• 2011
  Macho Fernandez E, Fernandez EM, Valenti V, Rockel C, Hermann C, Pot B, Boneca IG, Grangette C, Anti-inflammatory capacity of selected lactobacilli in experimental colitis is driven by NOD2-mediated recognition of a specific peptidoglycan-derived muropeptide, Gut 2011 Aug;60(8):1050-9.
• 2010
  Werts C, Leptospirosis: a Toll road from B lymphocytes, Chang Gung Med J 2010 Nov-Dec;33(6):591-601.
• 2010
  Bonis M, Ecobichon C, Guadagnini S, Prévost MC, Boneca IG, A M23B family metallopeptidase of Helicobacter pylori required for cell shape, pole formation and virulence, Mol. Microbiol. 2010 Nov;78(4):809-19.
• 2010
  Eberl G, Boneca IG, Bacteria and MAMP-induced morphogenesis of the immune system, Curr. Opin. Immunol. 2010 Aug;22(4):448-54.
• 2010
  Thiberge JM, Boursaux-Eude C, Lehours P, Dillies MA, Creno S, Coppée JY, Rouy Z, Lajus A, Ma L, Burucoa C, Ruskoné-Foumestraux A, Courillon-Mallet A, De Reuse H, Boneca IG, Lamarque D, Mégraud F, Delchier JC, Médigue C, Bouchier C, Labigne A, Raymond J, From array-based hybridization of Helicobacter pylori isolates to the complete genome sequence of an isolate associated with MALT lymphoma, BMC Genomics 2010;11:368.
• 2010
  Thiberge JM1, Boursaux-Eude C, Lehours P, Dillies MA, Creno S, Coppée JY, Rouy Z, Lajus A, Ma L, Burucoa C, Ruskoné-Foumestraux A, Courillon-Mallet A, De Reuse H, Boneca IG, Lamarque D, Mégraud F, Delchier JC, Médigue C, Bouchier C, Labigne A, Raymond J., From array-based hybridization of Helicobacter pylori isolates to the complete genome sequence of an isolate associated with MALT lymphoma., BMC Genomics. 2010 Jun 10;11:368. doi: 10.1186/1471-2164-11-368..
• 2010
  Foureau DM, Mielcarz DW, Menard LC, Schulthess J, Werts C, Vasseur V, Ryffel B, Kasper LH, Buzoni-Gatel D, TLR9-dependent induction of intestinal alpha-defensins by Toxoplasma gondii, J. Immunol. 2010 Jun;184(12):7022-9.
• 2009
  Grubman A, Kaparakis M, Viala J, Allison C, Badea L, Karrar A, Boneca IG, Le Bourhis L, Reeve S, Smith IA, Hartland EL, Philpott DJ, Ferrero RL, The innate immune molecule, NOD1, regulates direct killing of Helicobacter pylori by antimicrobial peptides, Cell. Microbiol. 2010 May;12(5):626-39.
• 2009
  Travassos LH, Carneiro LA, Ramjeet M, Hussey S, Kim YG, Magalhães JG, Yuan L, Soares F, Chea E, Le Bourhis L, Boneca IG, Allaoui A, Jones NL, Nuñez G, Girardin SE, Philpott DJ, Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry, Nat. Immunol. 2010 Jan;11(1):55-62.
• 2009
  Robins LI, Williams AH, Raetz CR, Structural basis for the sugar nucleotide and acyl-chain selectivity of Leptospira interrogans LpxA, Biochemistry 2009 Jul;48(26):6191-201.
• 2009
  Chaouche-Drider N, Kaparakis M, Karrar A, Fernandez MI, Carneiro LA, Viala J, Boneca IG, Moran AP, Philpott DJ, Ferrero RL, A commensal Helicobacter sp. of the rodent intestinal flora activates TLR2 and NOD1 responses in epithelial cells, PLoS ONE 2009;4(4):e5396.
• 2009
  Mkaddem SB, Werts C, Goujon JM, Bens M, Pedruzzi E, Ogier-Denis E, Vandewalle A, Heat shock protein gp96 interacts with protein phosphatase 5 and controls toll-like receptor 2 (TLR2)-mediated activation of extracellular signal-regulated kinase (ERK) 1/2 in post-hypoxic kidney cells, J. Biol. Chem. 2009 May;284(18):12541-9.
• 2009
  Boneca IG, Mammalian PGRPs in the spotlight, Cell Host Microbe 2009 Feb;5(2):109-11.
• 2008
  Bouskra D, Brézillon C, Bérard M, Werts C, Varona R, Boneca IG, Eberl G, Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis, Nature 2008 Nov;456(7221):507-10.
• 2008
  Hitotsumatsu O, Ahmad RC, Tavares R, Wang M, Philpott D, Turer EE, Lee BL, Shiffin N, Advincula R, Malynn BA, Werts C, Ma A, The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals, Immunity 2008 Mar;28(3):381-90.
• 2008
  Boneca IG, Ecobichon C, Chaput C, Mathieu A, Guadagnini S, Prévost MC, Colland F, Labigne A, de Reuse H, Development of inducible systems to engineer conditional mutants of essential genes of Helicobacter pylori, Appl. Environ. Microbiol. 2008 Apr;74(7):2095-102.
• 2007
  Williams AH, Raetz CR, Structural basis for the acyl chain selectivity and mechanism of UDP-N-acetylglucosamine acyltransferase, Proc. Natl. Acad. Sci. U.S.A. 2007 Aug;104(34):13543-50.
• 2006
  Francetic O, Buddelmeijer N, Lewenza S, Kumamoto CA, Pugsley AP, Signal recognition particle-dependent inner membrane targeting of the PulG Pseudopilin component of a type II secretion system, J. Bacteriol. 2007 Mar;189(5):1783-93.
• 2006
  Williams AH, Immormino RM, Gewirth DT, Raetz CR, Structure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial pentadecapeptide, Proc. Natl. Acad. Sci. U.S.A. 2006 Jul;103(29):10877-82.
• 2006
  Buddelmeijer N, Francetic O, Pugsley AP, Green fluorescent chimeras indicate nonpolar localization of pullulanase secreton components PulL and PulM, J. Bacteriol. 2006 Apr;188(8):2928-35.
• 2004
  Sweet CR, Williams AH, Karbarz MJ, Werts C, Kalb SR, Cotter RJ, Raetz CR, Enzymatic synthesis of lipid A molecules with four amide-linked acyl chains. LpxA acyltransferases selective for an analog of UDP-N-acetylglucosamine in which an amine replaces the 3″-hydroxyl group, J. Biol. Chem. 2004 Jun;279(24):25411-9.