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2020Structural evidence for the binding of monocarboxylates and dicarboxylates at pharmacologically relevant extracellular sites of a pentameric ligand-gated ion channel., Acta Crystallogr D Struct Biol 2020 Jul; 76(Pt 7): 668-675.
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2020Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA., Nat Commun 2020 03; 11(1): 1591.
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2019Structure of the DP1–DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases, PLOS Biology 17, e3000122 .
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2019Structure of the DP1-DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases, PLoS Biol. 2019 Jan;17(1):e3000122.
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2018Coarse-grained dynamics of supramolecules: Conformational changes in outer shells of Dengue viruses, Prog. Biophys. Mol. Biol. 2019 May;143:20-37.
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2018Combined approaches from physics, statistics, and computer science for protein structure prediction: (unity is strength)?, F1000Res 2018;7.
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2018Enzymatic synthesis of random sequences of RNA and RNA analogues by DNA polymerase theta mutants for the generation of aptamer libraries, Nucleic Acids Res. 2018 07;46(12):6271-6284.
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2018Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels, Cell Rep 2018 04;23(4):993-1004.
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2018Terminal deoxynucleotidyltransferase: the story of an untemplated DNA polymerase capable of DNA bridging and templated synthesis across strands, Curr. Opin. Struct. Biol. 2018 12;53:22-31.
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2018Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation, Proc. Natl. Acad. Sci. U.S.A. 2018 04;115(17):E3959-E3968.
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2017Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel, PLoS Biol. 2017 12;15(12):e2004470.
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2017String method solution of the gating pathways for a pentameric ligand-gated ion channel, Proc. Natl. Acad. Sci. U.S.A. 2017 05;114(21):E4158-E4167.
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2016Vaccination Against Human Papilloma Viruses Leads to a Favorable Cytokine Profile of Specific T Cells, J. Immunother. 2016 10;39(8):316-20.
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2016Structural Basis for Xenon Inhibition in a Cationic Pentameric Ligand-Gated Ion Channel, PLoS ONE 2016;11(2):e0149795.
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2015Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair, EMBO J. 2015 Apr;34(8):1126-42.
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2015Genuine open form of the pentameric ligand-gated ion channel GLIC, Acta Crystallogr. D Biol. Crystallogr. 2015 Mar;71(Pt 3):454-60.
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2015Allosteric and hyperekplexic mutant phenotypes investigated on an α1 glycine receptor transmembrane structure, Proc. Natl. Acad. Sci. U.S.A. 2015 Mar;112(9):2865-70.
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2014Crystallographic studies of pharmacological sites in pentameric ligand-gated ion channels, Biochim. Biophys. Acta 2015 Mar;1850(3):511-23.
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2014Enhanced amino acid selection in fully evolved tryptophanyl-tRNA synthetase, relative to its urzyme, requires domain motion sensed by the D1 switch, a remote dynamic packing motif, J. Biol. Chem. 2014 Feb;289(7):4367-76.
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2013New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target, J. Med. Chem. 2013 Sep;56(18):7431-41.
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2011X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel, Nature 2011 Jan;469(7330):428-31.
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2010Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase, PLoS ONE 2010 Aug;5(8):e12245.
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2002Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism, J. Biol. Chem. 2003 Feb;278(7):4963-71.
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