Aminoacyl-tRNA synthetases (aaRS) constitute a family of enzymes that catalyze the specific attachment of one amino acid (aa) to its cognate tRNA in what is a key step in the translation of the genetic information during protein biosynthesis. This enzymatic reaction requires ATP and can be decomposed in two steps:
The structure of a bacterial analog of the nicotinic receptor (one color per subunit) inserted into the cell membrane (grey and orange). A representation of the volume accessible to ions is shown in yellow.
Publication : Nucleic Acids and Molecular Biology book series