Assistant Professor, CR IP (PhD 1992 Paris XI, HDR 2009 Paris VI), biochemist /biophysicist.
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Publications
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2013Membrane microdomains and cytoskeleton organization shape and regulate the IL-7 receptor signalosome in human CD4 T-cells, J. Biol. Chem. 2013 Mar;288(12):8691-701.
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2011Interleukin (IL)-2 and IL-15 have different effects on human natural killer lymphocytes, Hum. Immunol. 2011 Nov;72(11):1013-7.
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2010KCNQ1 channels voltage dependence through a voltage-dependent binding of the S4-S5 linker to the pore domain, J. Biol. Chem. 2011 Jan;286(1):707-16.
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2010IL-2 induces conformational changes in its preassembled receptor core, which then migrates in lipid raft and binds to the cytoskeleton meshwork, J. Mol. Biol. 2010 Nov;403(5):671-92.
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2010Zinc induces structural reorganization of gelatin binding domain from human fibronectin and affects collagen binding, Structure 2010 Jun;18(6):710-8.
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2010Elucidation of the self-assembly pathway of lanreotide octapeptide into beta-sheet nanotubes: role of two stable intermediates, J. Am. Chem. Soc. 2010 Mar;132(12):4230-41.
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2010Interleukin-7 compartmentalizes its receptor signaling complex to initiate CD4 T lymphocyte response, J. Biol. Chem. 2010 May;285(20):14898-908.
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2009Identification and biochemical characterization of human plasma soluble IL-7R: lower concentrations in HIV-1-infected patients, J. Immunol. 2009 Jun;182(12):7389-97.
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2009A programmed switch from IL-15- to IL-2-dependent activation in human NK cells, J. Immunol. 2009 May;182(10):6267-77.
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2009Dimer disruption and monomer sequestration by alkyl tripeptides are successful strategies for inhibiting wild-type and multidrug-resistant mutated HIV-1 proteases, Biochemistry 2009 Jan;48(2):379-87.
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