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Natural Control of HIV-1 Infection
Asier Sáez-Cirión (PI)
HIV-controllers (HIC) (also called “elite controllers” or “elite suppressors”) are rare (less than 1%) HIV-infected patients who control viral replication to undetectable levels in the absence of antiretroviral treatment. In the context of the […]
2019Metabolic plasticity of HIV-specific CD8+ T cells is associated with enhanced antiviral potential and natural control of HIV-1 infection, Nat Metab 1, 704–716 (2019).
2018Cellular Metabolism Is a Major Determinant of HIV-1 Reservoir Seeding in CD4 T Cells and Offers an Opportunity to Tackle Infection, Cell Metab. 2018 Dec;.
2018Stage-specific IFN-induced and IFN gene expression reveal convergence of type I and type II IFN and highlight their role in both acute and chronic stage of pathogenic SIV infection., PLoS One. 2018 Feb 23;13(2):e0193629..
2017Ultrasensitive HIV-1 p24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents, J. Virol. 2017 03;91(6).
2016Elevated Basal Pre-infection CXCL10 in Plasma and in the Small Intestine after Infection Are Associated with More Rapid HIV/SIV Disease Onset, PLoS Pathog. 2016 Aug;12(8):e1005774.
2015HIV controllers with different viral load cutoff levels have distinct virologic and immunologic profiles, J. Acquir. Immune Defic. Syndr. 2015 Apr;68(4):377-85.
2014Association of single nucleotide polymorphisms in the lens epithelium-derived growth factor (LEDGF/p75) with HIV-1 infection outcomes in Brazilian HIV-1+ individuals, PLoS ONE 2014;9(7):e101780.
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