Timeline

Gabriel Aymé
Research Engineer
25 Sep 2023
publication

An original potentiating mechanism revealed by the cryo-EM structures of the human α7 nicotinic receptor in complex with nanobodies.

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22 Jun 2023
event

Single-Domain Antibodies 2023

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25 May 2023
publication

Generation of nanobodies acting as silent and positive allosteric modulators of the α7 nicotinic acetylcholine receptor.

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09 Mar 2023
publication

Development of Nanobodies as Theranostic Agents against CMY-2-Like Class C β-Lactamases.

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25 Oct 2022
project

Advances in cancer immunotherapy development: VHH-based immune checkpoint inhibitors targeting the receptor ILT4

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01 Jan 2022
publication

Development of a highly specific and sensitive VHH-based sandwich immunoassay for the detection of the SARS-CoV-2 nucleoprotein.

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10 Apr 2020
project

CORONABODIES

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07 Apr 2020
publication

Single-domain antibodies targeting antithrombin reduce bleeding in hemophilic mice with or without inhibitors.

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16 Jan 2020
project

VenoMATIcs: Toward a Global Management of Venoms and Envenomations: the Pasteur network Translational Approach

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13 Sep 2018
publication

A factor VIII-nanobody fusion protein forming an ultrastable complex with VWF: effect on clearance and antibody formation.

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01 Apr 2018
publication

Macrophage scavenger receptor SR-AI contributes to the clearance of von Willebrand factor.

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27 Feb 2018
project

Toxins and nanobodies as subtype-specific ligands and allosteric modulators of nicotinic acetylcholine receptors (PTR Nicobinder)

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01 Sep 2017
publication

A Novel Single-Domain Antibody Against von Willebrand Factor A1 Domain Resolves Leukocyte Recruitment and Vascular Leakage During Inflammation-Brief Report.

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27 Apr 2017
publication

Complex formation with pentraxin-2 regulates factor X plasma levels and macrophage interactions.

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06 Oct 2016
publication

LIM kinase/cofilin dysregulation promotes macrothrombocytopenia in severe von Willebrand disease-type 2B.

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17 Feb 2015
team

Antibody Engineering

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