Timeline

Fabrice Agou
Head of Facility
25 Sep 2019
publication

Two NEMO-like Ubiquitin-Binding Domains in CEP55 Differently Regulate Cytokinesis.

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29 Jan 2019
event

Virology Department Seminar : « Molecular mechanisms of enterovirus infection and search for anti-virals » with Varpu MARJOMÄKI

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13 Dec 2017
event

Scientific Day on Genome Editing Technology : CRISPR-Cas9 Seminar

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13 Dec 2017
event

Advancing scientific innovations with ECHO Acoustic Liquid Handling

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13 Dec 2017
event

The power of CRISPR-Cas9 arrayed screen using synthetic crRNA libraries

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27 Feb 2017
publication

Lack of interaction between NEMO and SHARPIN impairs linear ubiquitination and NF-κB activation and leads to incontinentia pigmenti.

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02 Sep 2016
publication

Super-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmenti

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27 Oct 2015
project

Microfluidics@Pasteur

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05 Jun 2015
team

Chemogenomic and Biological Screening Platform (PF-CCB)

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01 Jan 2015
publication

In vivo protein cross-linking

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01 Jan 2015
publication

Use of fluorescence spectroscopy for quantitative investigations of ubiquitin interactions with the ubiquitin-binding domains of NEMO

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20 Jan 2014
publication

TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO-IKK supramolecular structures

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07 Oct 2013
publication

Two-sided ubiquitin binding of NF-κB essential modulator (NEMO) zinc finger unveiled by a mutation associated with anhidrotic ectodermal dysplasia with immunodeficiency syndrome

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23 Jul 2011
publication

Direct inhibition of NF-κB activation by peptide targeting the NOA ubiquitin binding domain of NEMO

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01 Jan 2011
publication

Neuraminidase of 2007-2008 influenza A(H1N1) viruses shows increased affinity for sialic acids due to the D344N substitution

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23 Oct 2009
publication

DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding

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25 Nov 2008
publication

The zinc finger of NEMO is a functional ubiquitin-binding domain

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30 Jan 2008
publication

Solution structure of NEMO zinc finger and impact of an anhidrotic ectodermal dysplasia with immunodeficiency-related point mutation

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01 Sep 2007
publication

Inhibition of NF-kappaB activation with designed ankyrin-repeat proteins targeting the ubiquitin-binding/oligomerization domain of NEMO

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10 Apr 2007
publication

NEMO oligomerization in the dynamic assembly of the IkappaB kinase core complex

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23 Apr 2004
publication

The trimerization domain of NEMO is composed of the interacting C-terminal CC2 and LZ coiled-coil subdomains

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01 Jan 2004
publication

In vivo protein cross-linking

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