Ligne de temps
Fabrice Agou
Responsable de Plateforme
06 janv. 2024
publication
PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial.
Lire plus27 oct. 2023
event
ATC-DDS Seminar – “Epigenetic regulation: at the apex of Innate Immune Memory” – Pr. Musa M. Mhlanga (Radboud University, Netherlands)
Lire plus13 juil. 2023
event
2nd Drug Discovery & Screening Symposium – “From bench to drug discovery” – an ATC-DDS initiative
Lire plus21 avr. 2023
publication
Enhanced neutralization escape to therapeutic monoclonal antibodies by SARS-CoV-2 omicron sub-lineages.
Lire plus22 mars 2023
30 nov. 2022
publication
High-Content RNAi Phenotypic Screening Unveils the Involvement of Human Ubiquitin-Related Enzymes in Late Cytokinesis
Lire plus29 août 2022
04 juil. 2022
publication
Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.
Lire plus17 juin 2022
news
New publication – Potent Human Broadly SARS-CoV-2 Neutralizing IgA and IgG Antibodies Effective Against Omicron BA.1 and BA.2
Lire plus01 mai 2022
publication
A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors.
Lire plus27 sept. 2021
publication
Interrogating RNA and protein spatial subcellular distribution in smFISH data with DypFISH
Lire plus21 sept. 2021
publication
Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential.
Lire plus04 nov. 2019
publication
A sensitive fluorescence-based assay to monitor enzymatic activity of the essential integral membrane protein Apolipoprotein N-acyltransferase (Lnt).
Lire plus25 sept. 2019
publication
Two NEMO-like Ubiquitin-Binding Domains in CEP55 Differently Regulate Cytokinesis.
Lire plus29 janv. 2019
event
Virology Department Seminar : « Molecular mechanisms of enterovirus infection and search for anti-virals » with Varpu MARJOMÄKI
Lire plus13 déc. 2017
13 déc. 2017
13 déc. 2017
27 févr. 2017
publication
Lack of interaction between NEMO and SHARPIN impairs linear ubiquitination and NF-κB activation and leads to incontinentia pigmenti.
Lire plus02 sept. 2016
publication
Super-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmenti
Lire plus27 oct. 2015
05 juin 2015
01 févr. 2015
publication
Use of fluorescence spectroscopy for quantitative investigations of ubiquitin interactions with the ubiquitin-binding domains of NEMO
Lire plus01 janv. 2015
20 janv. 2014
publication
TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO-IKK supramolecular structures.
Lire plus23 juil. 2011
publication
Direct inhibition of NF-κB activation by peptide targeting the NOA ubiquitin binding domain of NEMO
Lire plus23 oct. 2009
publication
DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding
Lire plus25 nov. 2008
30 janv. 2008
publication
Solution structure of NEMO zinc finger and impact of an anhidrotic ectodermal dysplasia with immunodeficiency-related point mutation
Lire plus01 sept. 2007
publication
Inhibition of NF-kappaB activation with designed ankyrin-repeat proteins targeting the ubiquitin-binding/oligomerization domain of NEMO
Lire plus10 avr. 2007
publication
NEMO oligomerization in the dynamic assembly of the IkappaB kinase core complex
Lire plus23 avr. 2004
publication
The trimerization domain of NEMO is composed of the interacting C-terminal CC2 and LZ coiled-coil subdomains
Lire plus01 janv. 2004