Timeline
Etienne Patin
Permanent Researcher
31 Aug 2024
publication
Deep estimation of the intensity and timing of natural selection from ancient genomes.
Read more23 May 2024
publication
MANOCCA: a robust and computationally efficient test of covariance in high-dimension multivariate omics data.
Read more14 Feb 2024
01 Feb 2024
01 Dec 2023
publication
Unveiling Candida albicans intestinal carriage in healthy volunteers: the role of micro- and mycobiota, diet, host genetics and immune response.
Read more09 Aug 2023
22 Jun 2023
project
COVID-19-popCell – Genetic and infectious factors underlying population variability in immune responses to SARS-CoV-2
Read more16 Jan 2023
news
Highlighted paper: “Genetic adaptation to pathogens and increased risk of inflammatory disorders in post-Neolithic Europe”; Kerner et al. Cell Genomics, January 2023
Read more01 Jan 2023
publication
Unravelling the determinants of human health in French Polynesia: the MATAEA project.
Read more06 Oct 2022
08 Sep 2022
28 Jun 2022
publication
Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation.
Read more25 Apr 2022
11 Apr 2022
event
International Symposium – Genetic Admixture: Inference and Evolutionary Consequences – Monday 30th and Tuesday 31st May 2022
Read more09 Mar 2022
publication
Integrative genetic and immune cell analysis of plasma proteins in healthy donors identifies novel associations involving primary immune deficiency genes.
Read more01 Mar 2022
28 Oct 2021
01 Apr 2021
publication
Genomic insights into population history and biological adaptation in Oceania.
Read more04 Mar 2021
publication
Human ancient DNA analyses reveal the high burden of tuberculosis in Europeans over the last 2,000 years.
Read more04 Jan 2021
publication
Gut microbiome stability and dynamics in healthy donors and patients with non-gastrointestinal cancers.
Read more29 Jun 2020
01 Jan 2020
publication
Two common disease-associated TYK2 variants impact exon splicing and TYK2 dosage.
Read more01 Sep 2019
publication
A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals.
Read more08 Aug 2019
publication
Genomic Evidence for Local Adaptation of Hunter-Gatherers to the African Rainforest
Read more05 Sep 2018
publication
Human thymopoiesis is influenced by a common genetic variant within the TCRA-TCRD locus.
Read more27 Jul 2018
publication
Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines.
Read more14 Mar 2018
12 Mar 2018
publication
The demographic history and mutational load of African hunter-gatherers and farmers
Read more01 Mar 2018
publication
Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors.
Read more09 Nov 2017
publication
The Genetic Legacy of the Indian Ocean Slave Trade: Recent Admixture and Post-admixture Selection in the Makranis of Pakistan
Read more22 May 2017
05 May 2017
publication
Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America
Read more20 Oct 2016
publication
Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations
Read more19 Sep 2016
publication
Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations
Read more01 Jan 2016
publication
Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes
Read more30 Nov 2015
26 Nov 2015
19 Oct 2015
publication
The human gene damage index as a gene-level approach to prioritizing exome variants
Read more10 Sep 2015
10 Sep 2015
10 Sep 2015
11 May 2015
01 Apr 2015
publication
Automated flow cytometric analysis across large numbers of samples and cell types.
Read more11 Sep 2014
18 Aug 2014
publication
Adaptive, convergent origins of the pygmy phenotype in African rainforest hunter-gatherers
Read more01 Apr 2014
publication
Exploring the occurrence of classic selective sweeps in humans using whole-genome sequencing data sets
Read more03 Mar 2014
publication
Heterogeneous pattern of selective pressure for PRRT2 in human populations, but no association with autism spectrum disorders
Read more30 Jan 2014
publication
A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection
Read more01 Jan 2014
publication
The impact of agricultural emergence on the genetic history of African rainforest hunter-gatherers and agriculturalists
Read more15 Oct 2013
publication
A 1,100-year-old founder effect mutation in IL12B gene is responsible for Mendelian susceptibility to mycobacterial disease in Tunisian patients
Read more24 Sep 2013
publication
Human genetic data reveal contrasting demographic patterns between sedentary and nomadic populations that predate the emergence of farming
Read more12 Jul 2013
publication
Different selective pressures shape the evolution of Toll-like receptors in human and African great ape populations
Read more11 Apr 2013
publication
Ribosomal protein SA haploinsufficiency in humans with isolated congenital asplenia
Read more28 Dec 2012
publication
Positive selection in the chromosome 16 VKORC1 genomic region has contributed to the variability of anticoagulant response in humans
Read more27 Aug 2012
01 Aug 2012
publication
Human RHOH deficiency causes T cell defects and susceptibility to EV-HPV infections
Read more27 Jul 2012
publication
Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection
Read more28 Jun 2012
16 Dec 2011
publication
IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes
Read more12 Dec 2011
24 Aug 2011
publication
The selective footprints of viral pressures at the human RIG-I-like receptor family
Read more29 Mar 2011
publication
Evolutionary genetics evidence of an essential, nonredundant role of the IFN-γ pathway in protective immunity
Read more29 Jun 2010
publication
Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection
Read more22 Apr 2010
publication
Formulating a historical and demographic model of recent human evolution based on resequencing data from noncoding regions
Read more02 Mar 2010
publication
Parkinson’s disease-related LRRK2 G2019S mutation results from independent mutational events in humans
Read more11 Dec 2009
publication
Positively selected G6PD-Mahidol mutation reduces Plasmodium vivax density in Southeast Asians
Read more02 Sep 2009
17 Jul 2009
publication
Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense
Read more10 Apr 2009
publication
Inferring the demographic history of African farmers and pygmy hunter-gatherers using a multilocus resequencing data set
Read more19 Feb 2009
03 Feb 2008
23 Jan 2008
publication
Maternal traces of deep common ancestry and asymmetric gene flow between Pygmy hunter-gatherers and Bantu-speaking farmers
Read more11 Jan 2008
28 Nov 2007
publication
Population genetic diversity of the NAT2 gene supports a role of acetylation in human adaptation to farming in Central Asia
Read more02 Aug 2006
publication
Evolutionary insights into the high worldwide prevalence of MBL2 deficiency alleles
Read more01 Jul 2006
publication
Sub-Saharan African coding sequence variation and haplotype diversity at the NAT2 gene
Read more13 Jan 2006
publication
Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes
Read more29 Sep 2005
publication