Timeline

Etienne Patin
Permanent Researcher
29 Jun 2020
publication

Plague as a cause for familial Mediterranean fever.

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13 Sep 2019
publication

A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals.

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08 Aug 2019
publication

Genomic Evidence for Local Adaptation of Hunter-Gatherers to the African Rainforest

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05 Sep 2018
publication

Human thymopoiesis is influenced by a common genetic variant within the TCRA-TCRD locus.

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27 Jul 2018
publication

Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines.

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14 Mar 2018
publication

IRF4 haploinsufficiency in a family with Whipple’s disease

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12 Mar 2018
publication

The demographic history and mutational load of African hunter-gatherers and farmers

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01 Mar 2018
publication

Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors.

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09 Nov 2017
publication

The Genetic Legacy of the Indian Ocean Slave Trade: Recent Admixture and Post-admixture Selection in the Makranis of Pakistan

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22 May 2017
publication

Trends in DNA Methylation with Age Replicate Across Diverse Human Populations

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05 May 2017
publication

Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America

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20 Oct 2016
publication

Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations

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19 Sep 2016
publication

Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations

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01 Jan 2016
publication

Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes

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30 Nov 2015
publication

The epigenomic landscape of African rainforest hunter-gatherers and farmers

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26 Nov 2015
publication

Extensive Admixture and Selective Pressure Across the Sahel Belt

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19 Oct 2015
publication

The human gene damage index as a gene-level approach to prioritizing exome variants

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10 Sep 2015
project

ERC-2011-StG EVOIMMUNOPOP

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10 Sep 2015
project

The footprints of natural selection in the human genome

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10 Sep 2015
project

Human lifestyle and genetic and epigenetic variation

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11 May 2015
team

Human Evolutionary Genetics

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07 Jan 2015
publication

Automated flow cytometric analysis across large numbers of samples and cell types

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11 Sep 2014
publication

Impact of common risk factors of fibrosis progression in chronic hepatitis C

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18 Aug 2014
publication

Adaptive, convergent origins of the pygmy phenotype in African rainforest hunter-gatherers

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01 Apr 2014
publication

Exploring the occurrence of classic selective sweeps in humans using whole-genome sequencing data sets

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03 Mar 2014
publication

Heterogeneous pattern of selective pressure for PRRT2 in human populations, but no association with autism spectrum disorders

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30 Jan 2014
publication

A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection

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15 Oct 2013
publication

A 1,100-year-old founder effect mutation in IL12B gene is responsible for Mendelian susceptibility to mycobacterial disease in Tunisian patients

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24 Sep 2013
publication

Human genetic data reveal contrasting demographic patterns between sedentary and nomadic populations that predate the emergence of farming

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12 Jul 2013
publication

Different selective pressures shape the evolution of Toll-like receptors in human and African great ape populations

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11 Apr 2013
publication

Ribosomal protein SA haploinsufficiency in humans with isolated congenital asplenia

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28 Dec 2012
publication

Positive selection in the chromosome 16 VKORC1 genomic region has contributed to the variability of anticoagulant response in humans

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27 Aug 2012
publication

Inherited MST1 deficiency underlies susceptibility to EV-HPV infections

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01 Aug 2012
publication

Human RHOH deficiency causes T cell defects and susceptibility to EV-HPV infections

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27 Jul 2012
publication

Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection

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28 Jun 2012
publication

The evolutionary landscape of cytosolic microbial sensors in humans

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16 Dec 2011
publication

IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes

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12 Dec 2011
publication

Evolutionary genetic dissection of human interferons

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24 Aug 2011
publication

The selective footprints of viral pressures at the human RIG-I-like receptor family

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29 Mar 2011
publication

Evolutionary genetics evidence of an essential, nonredundant role of the IFN-γ pathway in protective immunity

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29 Jun 2010
publication

Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection

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22 Apr 2010
publication

Formulating a historical and demographic model of recent human evolution based on resequencing data from noncoding regions

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02 Mar 2010
publication

Parkinson’s disease-related LRRK2 G2019S mutation results from independent mutational events in humans

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11 Dec 2009
publication

Positively selected G6PD-Mahidol mutation reduces Plasmodium vivax density in Southeast Asians

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02 Sep 2009
publication

Evolutionary trajectories of primate genes involved in HIV pathogenesis

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17 Jul 2009
publication

Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense

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10 Apr 2009
publication

Inferring the demographic history of African farmers and pygmy hunter-gatherers using a multilocus resequencing data set

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19 Feb 2009
publication

Signatures of purifying and local positive selection in human miRNAs

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03 Feb 2008
publication

Natural selection has driven population differentiation in modern humans

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23 Jan 2008
publication

Maternal traces of deep common ancestry and asymmetric gene flow between Pygmy hunter-gatherers and Bantu-speaking farmers

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11 Jan 2008
publication

Demeter’s legacy: rapid changes to our genome imposed by diet

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28 Nov 2007
publication

Population genetic diversity of the NAT2 gene supports a role of acetylation in human adaptation to farming in Central Asia

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02 Aug 2006
publication

Evolutionary insights into the high worldwide prevalence of MBL2 deficiency alleles

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01 Jul 2006
publication

Sub-Saharan African coding sequence variation and haplotype diversity at the NAT2 gene

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13 Jan 2006
publication

Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes

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29 Sep 2005
publication

The heritage of pathogen pressures and ancient demography in the human innate-immunity CD209/CD209L region

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