Ligne de temps
Etienne Patin
Chercheur(euse) Permanent(e)
14 févr. 2024
01 févr. 2024
01 déc. 2023
publication
Unveiling Candida albicans intestinal carriage in healthy volunteers: the role of micro- and mycobiota, diet, host genetics and immune response.
Lire plus09 août 2023
22 juin 2023
project
COVID-19-popCell – Genetic and infectious factors underlying population variability in immune responses to SARS-CoV-2
Lire plus16 janv. 2023
news
Highlighted paper: “Genetic adaptation to pathogens and increased risk of inflammatory disorders in post-Neolithic Europe”; Kerner et al. Cell Genomics, January 2023
Lire plus01 janv. 2023
publication
Unravelling the determinants of human health in French Polynesia: the MATAEA project.
Lire plus06 oct. 2022
08 sept. 2022
28 juin 2022
publication
Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation.
Lire plus25 avr. 2022
11 avr. 2022
event
International Symposium – Genetic Admixture: Inference and Evolutionary Consequences – Monday 30th and Tuesday 31st May 2022
Lire plus09 mars 2022
publication
Integrative genetic and immune cell analysis of plasma proteins in healthy donors identifies novel associations involving primary immune deficiency genes.
Lire plus01 mars 2022
28 oct. 2021
01 avr. 2021
publication
Genomic insights into population history and biological adaptation in Oceania.
Lire plus04 mars 2021
publication
Human ancient DNA analyses reveal the high burden of tuberculosis in Europeans over the last 2,000 years.
Lire plus04 janv. 2021
publication
Gut microbiome stability and dynamics in healthy donors and patients with non-gastrointestinal cancers.
Lire plus29 juin 2020
01 janv. 2020
publication
Two common disease-associated TYK2 variants impact exon splicing and TYK2 dosage.
Lire plus01 sept. 2019
publication
A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals.
Lire plus08 août 2019
publication
Genomic Evidence for Local Adaptation of Hunter-Gatherers to the African Rainforest
Lire plus05 sept. 2018
publication
Human thymopoiesis is influenced by a common genetic variant within the TCRA-TCRD locus.
Lire plus27 juil. 2018
publication
Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines.
Lire plus14 mars 2018
12 mars 2018
publication
The demographic history and mutational load of African hunter-gatherers and farmers
Lire plus01 mars 2018
publication
Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors.
Lire plus09 nov. 2017
publication
The Genetic Legacy of the Indian Ocean Slave Trade: Recent Admixture and Post-admixture Selection in the Makranis of Pakistan
Lire plus22 mai 2017
05 mai 2017
publication
Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America
Lire plus20 oct. 2016
publication
Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations
Lire plus19 sept. 2016
publication
Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations
Lire plus01 janv. 2016
publication
Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes
Lire plus30 nov. 2015
26 nov. 2015
19 oct. 2015
publication
The human gene damage index as a gene-level approach to prioritizing exome variants
Lire plus10 sept. 2015
10 sept. 2015
10 sept. 2015
11 mai 2015
01 avr. 2015
publication
Automated flow cytometric analysis across large numbers of samples and cell types.
Lire plus11 sept. 2014
18 août 2014
publication
Adaptive, convergent origins of the pygmy phenotype in African rainforest hunter-gatherers
Lire plus01 avr. 2014
publication
Exploring the occurrence of classic selective sweeps in humans using whole-genome sequencing data sets
Lire plus03 mars 2014
publication
Heterogeneous pattern of selective pressure for PRRT2 in human populations, but no association with autism spectrum disorders
Lire plus30 janv. 2014
publication
A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection
Lire plus01 janv. 2014
publication
The impact of agricultural emergence on the genetic history of African rainforest hunter-gatherers and agriculturalists
Lire plus15 oct. 2013
publication
A 1,100-year-old founder effect mutation in IL12B gene is responsible for Mendelian susceptibility to mycobacterial disease in Tunisian patients
Lire plus24 sept. 2013
publication
Human genetic data reveal contrasting demographic patterns between sedentary and nomadic populations that predate the emergence of farming
Lire plus12 juil. 2013
publication
Different selective pressures shape the evolution of Toll-like receptors in human and African great ape populations
Lire plus11 avr. 2013
publication
Ribosomal protein SA haploinsufficiency in humans with isolated congenital asplenia
Lire plus28 déc. 2012
publication
Positive selection in the chromosome 16 VKORC1 genomic region has contributed to the variability of anticoagulant response in humans
Lire plus27 août 2012
01 août 2012
publication
Human RHOH deficiency causes T cell defects and susceptibility to EV-HPV infections
Lire plus27 juil. 2012
publication
Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection
Lire plus28 juin 2012
16 déc. 2011
publication
IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes
Lire plus12 déc. 2011
24 août 2011
publication
The selective footprints of viral pressures at the human RIG-I-like receptor family
Lire plus29 mars 2011
publication
Evolutionary genetics evidence of an essential, nonredundant role of the IFN-γ pathway in protective immunity
Lire plus29 juin 2010
publication
Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection
Lire plus22 avr. 2010
publication
Formulating a historical and demographic model of recent human evolution based on resequencing data from noncoding regions
Lire plus02 mars 2010
publication
Parkinson’s disease-related LRRK2 G2019S mutation results from independent mutational events in humans
Lire plus11 déc. 2009
publication
Positively selected G6PD-Mahidol mutation reduces Plasmodium vivax density in Southeast Asians
Lire plus02 sept. 2009
17 juil. 2009
publication
Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense
Lire plus10 avr. 2009
publication
Inferring the demographic history of African farmers and pygmy hunter-gatherers using a multilocus resequencing data set
Lire plus19 févr. 2009
03 févr. 2008
23 janv. 2008
publication
Maternal traces of deep common ancestry and asymmetric gene flow between Pygmy hunter-gatherers and Bantu-speaking farmers
Lire plus11 janv. 2008
28 nov. 2007
publication
Population genetic diversity of the NAT2 gene supports a role of acetylation in human adaptation to farming in Central Asia
Lire plus02 août 2006
publication
Evolutionary insights into the high worldwide prevalence of MBL2 deficiency alleles
Lire plus01 juil. 2006
publication
Sub-Saharan African coding sequence variation and haplotype diversity at the NAT2 gene
Lire plus13 janv. 2006
publication
Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes
Lire plus29 sept. 2005
publication