Timeline

Abdelkader Namane

Research Engineer

01 Jan 2022

publication

Composition and Dynamics of Protein Complexes Measured by Quantitative Mass Spectrometry of Affinity-Purified Samples.

08 Dec 2020

publication

A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.

04 Jun 2020

publication

Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes.

04 Feb 2020

project

Cytoplasmic mRNA degradation pathways

31 Jan 2020

project

Translation and Ribosome rescue

07 Jun 2019

publication

A specialised SKI complex assists the cytoplasmic RNA exosome in the absence of direct association with ribosomes

01 Oct 2018

publication

Nonsense-mediated mRNA decay involves two distinct Upf1-bound complexes

15 Mar 2017

publication

The ribosome-bound quality control complex remains associated to aberrant peptides during their proteasomal targeting and interacts with Tom1 to limit protein aggregation

16 Dec 2016

publication

The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex

05 Dec 2016

publication

Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins

22 Jul 2016

publication

Role of the N-Acetylmuramoyl-l-Alanyl Amidase, AmiA, of Helicobacter pylori in Peptidoglycan Metabolism, Daughter Cell Separation, and Virulence

18 Apr 2016

publication

Rqc1 and Ltn1 Prevent C-terminal Alanine-Threonine Tail (CAT-tail)-induced Protein Aggregation by Efficient Recruitment of Cdc48 on Stalled 60S Subunits

02 Sep 2015

project

Quality Control at the Ribosome

16 Jul 2015

team

Quality Control at the Ribosome

09 Jun 2015

project

Non-sense mediated mRNA decay mechanisms

16 Apr 2014

publication

Proteomic analysis of intact flagella of procyclic Trypanosoma brucei cells identifies novel flagellar proteins with unique sub-localization and dynamics

01 Feb 2014

publication

Isolation, functional characterization and proteomic identification of CC2-PLA₂ from Cerastes cerastes venom: a basic platelet-aggregation-inhibiting factor

02 Nov 2013

publication

Differential expression of Ixodes ricinus salivary gland proteins in the presence of the Borrelia burgdorferi sensu lato complex

13 Aug 2013

publication

Yeast ribosomal protein L7 and its homologue Rlp7 are simultaneously present at distinct sites on pre-60S ribosomal particles

11 Mar 2013

publication

Cdc48-associated complex bound to 60S particles is required for the clearance of aberrant translation products

07 Jan 2013

publication

A minimal bacterial RNase J-based degradosome is associated with translating ribosomes.

05 Jan 2013

publication

New markers in Anopheles gambiae salivary glands after Plasmodium berghei infection

15 Nov 2012

publication

Infection by chikungunya virus modulates the expression of several proteins in Aedes aegypti salivary glands

22 Oct 2012

publication

A minimal bacterial RNase J-based degradosome is associated with translating ribosomes

04 Sep 2012

publication

Identification of Outer Membrane Proteins Altered in Response to UVC-Radiation in Vibrio parahaemolyticus and Vibrio alginolyticus

17 Nov 2011

publication

A critical role of perinuclear filamentous actin in spatial repositioning and mutually exclusive expression of virulence genes in malaria parasites

01 May 2011

publication

Characterization of the antibody response to the saliva of Phlebotomus papatasi in people living in endemic areas of cutaneous leishmaniasis

01 Nov 2010

publication

Identification of Leishmania-specific protein phosphorylation sites by LC-ESI-MS/MS and comparative genomics analyses

28 Oct 2010

publication

Identification of outer membrane proteins of Vibrio parahaemolyticus and Vibrio alginolyticus altered in response to γ-irradiation or long-term starvation

01 Oct 2010

publication

CCSV-MPase, a novel procoagulant metalloproteinase from Cerastes cerastes venom: purification, biochemical characterization and protein identification

19 Apr 2010

publication

Phosphoproteome dynamics reveal heat-shock protein complexes specific to the Leishmania donovani infectious stage

01 Apr 2010

publication

AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting with histone H2AX

18 Feb 2010

publication

Interleukin-7 compartmentalizes its receptor signaling complex to initiate CD4 T lymphocyte response

14 Dec 2009

publication

IgG autoantibody to brain beta tubulin III associated with cytokine cluster-II discriminate cerebral malaria in central India

04 Aug 2008

publication

In vivo interactome of Helicobacter pylori urease revealed by tandem affinity purification

01 Aug 2008

publication

Comprehensive proteome analysis of Mycobacterium ulcerans and quantitative comparison of mycolactone biosynthesis

25 Jul 2008

publication

60S ribosomal subunit assembly dynamics defined by semi-quantitative mass spectrometry of purified complexes

01 Jan 2008

publication

Phosphoproteomic analysis of Leishmania donovani pro- and amastigote stages

01 Dec 2007

publication

The HcaR regulatory protein of Photorhabdus luminescens affects the production of proteins involved in oxidative stress and toxemia

01 Sep 2007

publication

The salivary glands and saliva of Anopheles gambiae as an essential step in the Plasmodium life cycle: a global proteomic study

21 May 2007

publication

The Pseudomonas aeruginosa LasB metalloproteinase regulates the human urokinase-type plasminogen activator receptor through domain-specific endoproteolysis

25 Apr 2007

publication

Self-reactivities to the non-erythroid alpha spectrin correlate with cerebral malaria in Gabonese children

16 Feb 2007

publication

The p21-activated protein kinase inhibitor Skb15 and its budding yeast homologue are 60S ribosome assembly factors

16 Jan 2007

publication

A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system.

27 Jul 2006

publication

Yeast homolog of a cancer-testis antigen defines a new transcription complex

16 Sep 2005

publication

Deletion of EFL1 results in heterogeneity of the 60 S GTPase-associated rRNA conformation

01 Sep 2005

publication

Limited efficiency of prolyl-endopeptidase in the detoxification of gliadin peptides in celiac disease

01 Jul 2005

publication

Immunogenic membrane-associated proteins of Mycobacterium tuberculosis revealed by proteomics

01 Jun 2005

publication

Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase

01 May 2005

publication

LANCL1, an erythrocyte protein recruited to the Maurer’s clefts during Plasmodium falciparum development

27 Jan 2005

publication

Staphylococcus aureus RNAIII and the endoribonuclease III coordinately regulate spa gene expression

10 Sep 2004

publication

Plasmin cleaves the juxtamembrane domain and releases truncated species of the urokinase receptor (CD87) from human bronchial epithelial cells

01 May 2004

publication

Global analysis of gene expression in an rpoN mutant of Listeria monocytogenes

01 Apr 2004

publication

AstR-AstS, a new two-component signal transduction system, mediates swarming, adaptation to stationary phase and phenotypic variation in Photorhabdus luminescens

01 Jan 2004

publication

Proteolytic regulation of the urokinase receptor/CD87 on monocytic cells by neutrophil elastase and cathepsin G

01 Sep 2003

publication

Alterations of the intestinal transport and processing of gliadin peptides in celiac disease

01 Jul 2003

publication

Sequential protein association with nascent 60S ribosomal particles

01 Nov 2002

publication

Structural and nucleotide-binding properties of YajQ and YnaF, two Escherichia coli proteins of unknown function

01 Oct 2002

publication

A proteomic analysis of the salt stress response of Listeria monocytogenes

24 Sep 2002

publication

A proteomic study of Escherichia coli O157:H7 NCTC 12900 cultivated in biofilm or in planktonic growth mode

23 Apr 2002

publication

Comparison of protein patterns of Listeria monocytogenes grown in biofilm or in planktonic mode by proteomic analysis

01 Mar 2002

publication

Spc24 interacts with Mps2 and is required for chromosome segregation, but is not implicated in spindle pole body duplication

01 Jan 2002

publication

Proteome analysis of the plasma membrane of Mycobacterium tuberculosis

27 Nov 2001

publication

A yeast homolog of chromatin assembly factor 1 is involved in early ribosome assembly

15 Nov 2001

publication

Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps

14 Feb 2001

publication

Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues

15 Jan 2001

publication

Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes

01 Jan 2001

publication

Nonspecific B and T cell-stimulatory activity mediated by mast cells is associated with exosomes

01 Feb 2000

publication

Genetic and biochemical characterization of Salmonella enterica serovar typhi deoxyribokinase

01 Nov 1999

publication

Decreased capacity of recombinant 45/47-kDa molecules (Apa) of Mycobacterium tuberculosis to stimulate T lymphocyte responses related to changes in their mannosylation pattern

01 Nov 1999

publication

Deglycosylation of the 45/47-kilodalton antigen complex of Mycobacterium tuberculosis decreases its capacity to elicit in vivo or in vitro cellular immune responses

01 Aug 1999

publication

Abnormal DNA methylation and deoxycytosine-deoxyguanine content in nucleosomes from lymphocytes undergoing apoptosis

01 Jul 1999

publication

Assay of nucleoside 2-deoxyribosyltransferase activity with pyruvate kinase/lactate dehydrogenase coupling system

01 Mar 1999

publication

Unusual nucleotide conformations in GNRA and UNCG type tetraloop hairpins: evidence from Raman markers assignments

26 May 1998

publication

Structural features of the UCCG and UGCG tetraloops in very short hairpins as evidenced by optical spectroscopy

01 May 1997

publication

Prochlorothrix hollandica PCC 9006: genomic properties of an axenic representative of the chlorophyll a/b-containing oxyphotobacteria

01 Apr 1997

publication

Common structural features of UUCG and UACG tetraloops in very short hairpins determined by UV absorption, Raman, IR and NMR spectroscopies

10 Dec 1995

publication

Chemienzymatic synthesis of uridine nucleotides labeled with [15N] and [13C]

01 Oct 1993

publication

Enzymatic synthesis of some O-beta-D-digalactosyl glycopeptides, using beta-D-galactosidase

01 Jan 1993

publication

Influence of glucose on the deoxyglucose metabolism in S cerevisiae: detection and identification of deoxyglucose and trehalose derivatives by 1H- and 13C-NMR spectroscopy

01 Aug 1992

publication

Improved brain delivery of AZT using a glycosyl phosphotriester prodrug

15 Feb 1991

publication

1H- and 31P-NMR studies of ditercalinium binding to a d(GCGC)2 and d(CCTATAGG)2 minihelices: a sequence specificity study

01 Mar 1989

publication

A little guide for advanced search:

Composition and Dynamics of Protein Complexes Measured by Quantitative Mass Spectrometry of Affinity-Purified Samples.

A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.

Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes.

Cytoplasmic mRNA degradation pathways

Translation and Ribosome rescue

A specialised SKI complex assists the cytoplasmic RNA exosome in the absence of direct association with ribosomes

Nonsense-mediated mRNA decay involves two distinct Upf1-bound complexes

The ribosome-bound quality control complex remains associated to aberrant peptides during their proteasomal targeting and interacts with Tom1 to limit protein aggregation

The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex

Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins

Role of the N-Acetylmuramoyl-l-Alanyl Amidase, AmiA, of Helicobacter pylori in Peptidoglycan Metabolism, Daughter Cell Separation, and Virulence

Rqc1 and Ltn1 Prevent C-terminal Alanine-Threonine Tail (CAT-tail)-induced Protein Aggregation by Efficient Recruitment of Cdc48 on Stalled 60S Subunits

Quality Control at the Ribosome

Quality Control at the Ribosome

Non-sense mediated mRNA decay mechanisms

Proteomic analysis of intact flagella of procyclic Trypanosoma brucei cells identifies novel flagellar proteins with unique sub-localization and dynamics

Isolation, functional characterization and proteomic identification of CC2-PLA₂ from Cerastes cerastes venom: a basic platelet-aggregation-inhibiting factor

Differential expression of Ixodes ricinus salivary gland proteins in the presence of the Borrelia burgdorferi sensu lato complex

Yeast ribosomal protein L7 and its homologue Rlp7 are simultaneously present at distinct sites on pre-60S ribosomal particles

Cdc48-associated complex bound to 60S particles is required for the clearance of aberrant translation products

A minimal bacterial RNase J-based degradosome is associated with translating ribosomes.

New markers in Anopheles gambiae salivary glands after Plasmodium berghei infection

Infection by chikungunya virus modulates the expression of several proteins in Aedes aegypti salivary glands

A minimal bacterial RNase J-based degradosome is associated with translating ribosomes

Identification of Outer Membrane Proteins Altered in Response to UVC-Radiation in Vibrio parahaemolyticus and Vibrio alginolyticus

A critical role of perinuclear filamentous actin in spatial repositioning and mutually exclusive expression of virulence genes in malaria parasites

Characterization of the antibody response to the saliva of Phlebotomus papatasi in people living in endemic areas of cutaneous leishmaniasis

Identification of Leishmania-specific protein phosphorylation sites by LC-ESI-MS/MS and comparative genomics analyses

Identification of outer membrane proteins of Vibrio parahaemolyticus and Vibrio alginolyticus altered in response to γ-irradiation or long-term starvation

CCSV-MPase, a novel procoagulant metalloproteinase from Cerastes cerastes venom: purification, biochemical characterization and protein identification

Phosphoproteome dynamics reveal heat-shock protein complexes specific to the Leishmania donovani infectious stage

AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting with histone H2AX

Interleukin-7 compartmentalizes its receptor signaling complex to initiate CD4 T lymphocyte response

IgG autoantibody to brain beta tubulin III associated with cytokine cluster-II discriminate cerebral malaria in central India

In vivo interactome of Helicobacter pylori urease revealed by tandem affinity purification

Comprehensive proteome analysis of Mycobacterium ulcerans and quantitative comparison of mycolactone biosynthesis

60S ribosomal subunit assembly dynamics defined by semi-quantitative mass spectrometry of purified complexes

Phosphoproteomic analysis of Leishmania donovani pro- and amastigote stages

The HcaR regulatory protein of Photorhabdus luminescens affects the production of proteins involved in oxidative stress and toxemia

The salivary glands and saliva of Anopheles gambiae as an essential step in the Plasmodium life cycle: a global proteomic study

The Pseudomonas aeruginosa LasB metalloproteinase regulates the human urokinase-type plasminogen activator receptor through domain-specific endoproteolysis

Self-reactivities to the non-erythroid alpha spectrin correlate with cerebral malaria in Gabonese children

The p21-activated protein kinase inhibitor Skb15 and its budding yeast homologue are 60S ribosome assembly factors

A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system.

Yeast homolog of a cancer-testis antigen defines a new transcription complex

Deletion of EFL1 results in heterogeneity of the 60 S GTPase-associated rRNA conformation

Limited efficiency of prolyl-endopeptidase in the detoxification of gliadin peptides in celiac disease

Immunogenic membrane-associated proteins of Mycobacterium tuberculosis revealed by proteomics

Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase

LANCL1, an erythrocyte protein recruited to the Maurer’s clefts during Plasmodium falciparum development

Staphylococcus aureus RNAIII and the endoribonuclease III coordinately regulate spa gene expression

Plasmin cleaves the juxtamembrane domain and releases truncated species of the urokinase receptor (CD87) from human bronchial epithelial cells

Global analysis of gene expression in an rpoN mutant of Listeria monocytogenes

AstR-AstS, a new two-component signal transduction system, mediates swarming, adaptation to stationary phase and phenotypic variation in Photorhabdus luminescens

Proteolytic regulation of the urokinase receptor/CD87 on monocytic cells by neutrophil elastase and cathepsin G

Alterations of the intestinal transport and processing of gliadin peptides in celiac disease

Sequential protein association with nascent 60S ribosomal particles

Structural and nucleotide-binding properties of YajQ and YnaF, two Escherichia coli proteins of unknown function

A proteomic analysis of the salt stress response of Listeria monocytogenes

A proteomic study of Escherichia coli O157:H7 NCTC 12900 cultivated in biofilm or in planktonic growth mode

Comparison of protein patterns of Listeria monocytogenes grown in biofilm or in planktonic mode by proteomic analysis

Spc24 interacts with Mps2 and is required for chromosome segregation, but is not implicated in spindle pole body duplication

Proteome analysis of the plasma membrane of Mycobacterium tuberculosis

A yeast homolog of chromatin assembly factor 1 is involved in early ribosome assembly

Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps

Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues

Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes

Nonspecific B and T cell-stimulatory activity mediated by mast cells is associated with exosomes

Genetic and biochemical characterization of Salmonella enterica serovar typhi deoxyribokinase

Decreased capacity of recombinant 45/47-kDa molecules (Apa) of Mycobacterium tuberculosis to stimulate T lymphocyte responses related to changes in their mannosylation pattern

Deglycosylation of the 45/47-kilodalton antigen complex of Mycobacterium tuberculosis decreases its capacity to elicit in vivo or in vitro cellular immune responses

Abnormal DNA methylation and deoxycytosine-deoxyguanine content in nucleosomes from lymphocytes undergoing apoptosis

Assay of nucleoside 2-deoxyribosyltransferase activity with pyruvate kinase/lactate dehydrogenase coupling system

Unusual nucleotide conformations in GNRA and UNCG type tetraloop hairpins: evidence from Raman markers assignments

Structural features of the UCCG and UGCG tetraloops in very short hairpins as evidenced by optical spectroscopy

Prochlorothrix hollandica PCC 9006: genomic properties of an axenic representative of the chlorophyll a/b-containing oxyphotobacteria

Common structural features of UUCG and UACG tetraloops in very short hairpins determined by UV absorption, Raman, IR and NMR spectroscopies

Chemienzymatic synthesis of uridine nucleotides labeled with [15N] and [13C]

Enzymatic synthesis of some O-beta-D-digalactosyl glycopeptides, using beta-D-galactosidase