Timeline

Laura Gomez Valero

Permanent Researcher

22 Dec 2023

project

From the source to the user end: deciphering the impact of microbiome and water parameters on opportunistic waterborne pathogens (MicroPathWater)

03 Nov 2023

publication

Structural basis for the toxicity of Legionella pneumophila effector SidH.

05 Oct 2023

publication

The SET and ankyrin domains of the secreted Legionella pneumophila histone methyltransferase work together to modify host chromatin.

10 Aug 2022

publication

Bacterial methyltransferases: targeting bacterial genomes to host epigenetics

15 Jul 2022

publication

Genomic erosion and horizontal gene transfer shape functional differences of the ExlA toxin in Pseudomonas spp.

16 Feb 2022

publication

The evolution and role of eukaryotic-like domains in environmental intracellular bacteria: the battle with a eukaryotic cell.

29 Nov 2021

publication

Patho-epigenetics: histone deacetylases as targets of pathogens and therapeutics

27 Jul 2020

publication

Evolution and function of bacterial RCC1 repeat effectors.

24 Jul 2020

publication

Metagenomic approaches in microbial ecology: an update on whole-genome and marker gene sequencing analyses.

24 Mar 2020

publication

Divergent Evolution of Legionella RCC1 Repeat Effectors Defines the Range of Ran GTPase Cycle Targets.

24 Jan 2020

publication

Legionnaires’ Disease: State of the Art Knowledge of Pathogenesis Mechanisms of Legionella.

27 Aug 2019

publication

Evolutionary dissection of the Dot/Icm system based on comparative genomics of 58 Legionella species

20 May 2019

publication

Intracellular parasitism, the driving force of evolution of Legionella pneumophila and the genus Legionella.

05 Feb 2019

publication

More than 18,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells.

31 Jan 2019

news

How human pathogens may emerge from the environment

08 Jan 2019

publication

The pleotropic Legionella transcription factor LvbR links the Lqs and c-di-GMP regulatory networks to control biofilm architecture and virulence

01 Sep 2018

publication

Targeting of RNA Polymerase II by a nuclear Legionella pneumophila Dot/Icm effector SnpL.

09 May 2018

publication

Short genome report of cellulose-producing commensal Escherichia coli 1094.

01 Jan 2017

publication

Biological Diversity and Evolution of Type IV Secretion Systems

30 Nov 2016

publication

Rapid detection and evolutionary analysis of Legionella pneumophila serogroup 1 sequence type 47

01 Nov 2016

publication

Multiple major disease-associated clones of Legionella pneumophila have emerged recently and independently.

13 May 2016

publication

Molecular epidemiology, phylogeny and evolution of Legionella

01 Aug 2015

publication

Bacterial remodelling of the host epigenome: functional role and evolution of effectors methylating host histones

11 May 2015

team

Biology Of Intracellular Bacteria

01 Jan 2014

publication

Comparative analyses of Legionella species identifies genetic features of strains causing Legionnaires’ disease

19 Aug 2013

publication

The Legionella pneumophila kai operon is implicated in stress response and confers fitness in competitive environments

01 Jun 2013

publication

Genome dynamics in Legionella: the basis of versatility and adaptation to intracellular replication.

17 Apr 2013

publication

Legionella pneumophila effector RomA uniquely modifies host chromatin to repress gene expression and promote intracellular bacterial replication

01 Jan 2013

publication

From amoeba to macrophages: exploring the molecular mechanisms of Legionella pneumophila infection in both hosts.

15 Jul 2012

publication

Characterization of an acetyltransferase that detoxifies aromatic chemicals in Legionella pneumophila.

01 Nov 2011

publication

Extensive recombination events and horizontal gene transfer shaped the Legionella pneumophila genomes.

28 Oct 2011

publication

Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions.

30 Dec 2010

publication

Specific real-time PCR for simultaneous detection and identification of Legionella pneumophila serogroup 1 in water and clinical samples.

06 Dec 2010

publication

Circadian clock proteins in prokaryotes: hidden rhythms?

26 May 2010

publication

The origins of eukaryotic-like proteins in Legionella pneumophila.

25 Mar 2010

publication

The Legionella pneumophila F-box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication

19 Feb 2010

publication

Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires’ disease.

01 Oct 2009

publication

Comparative sequence analysis of Mycobacterium leprae and the new leprosy-causing Mycobacterium lepromatosis.

01 Sep 2009

publication

Legionella pneumophila: population genetics, phylogeny and genomics.

19 Aug 2009

publication

Legionella pneumophila – Host Interactions: Insights Gained from Comparative Genomics and Cell Biology.

01 Aug 2009

publication

Molecular mimicry: an important virulence strategy employed by Legionella pneumophila to subvert host functions.

01 Oct 2008

publication

Patterns and rates of nucleotide substitution, insertion and deletion in the endosymbiont of ants Blochmannia floridanus.

30 Sep 2008

publication

Endosymbiont gene functions impaired and rescued by polymerase infidelity at poly(A) tracts.

01 Jul 2008

publication

Evolution of the secondary symbiont “Candidatus serratia symbiotica” in aphid species of the subfamily lachninae.

10 Jul 2007

publication

Reconstructing the ancestor of Mycobacterium leprae: the dynamics of gene loss and genome reduction.

01 Mar 2007

publication

Genome reduction of the aphid endosymbiont Buchnera aphidicola in a recent evolutionary time scale.

01 Nov 2004

publication

The evolutionary fate of nonfunctional DNA in the bacterial endosymbiont Buchnera aphidicola.

01 Oct 2004

publication

Coexistence of Wolbachia with Buchnera aphidicola and a secondary symbiont in the aphid Cinara cedri.

01 May 2002

publication

A little guide for advanced search:

From the source to the user end: deciphering the impact of microbiome and water parameters on opportunistic waterborne pathogens (MicroPathWater)

Structural basis for the toxicity of Legionella pneumophila effector SidH.

The SET and ankyrin domains of the secreted Legionella pneumophila histone methyltransferase work together to modify host chromatin.

Bacterial methyltransferases: targeting bacterial genomes to host epigenetics

Genomic erosion and horizontal gene transfer shape functional differences of the ExlA toxin in Pseudomonas spp.

The evolution and role of eukaryotic-like domains in environmental intracellular bacteria: the battle with a eukaryotic cell.

Patho-epigenetics: histone deacetylases as targets of pathogens and therapeutics

Evolution and function of bacterial RCC1 repeat effectors.

Metagenomic approaches in microbial ecology: an update on whole-genome and marker gene sequencing analyses.

Divergent Evolution of Legionella RCC1 Repeat Effectors Defines the Range of Ran GTPase Cycle Targets.

Legionnaires’ Disease: State of the Art Knowledge of Pathogenesis Mechanisms of Legionella.

Evolutionary dissection of the Dot/Icm system based on comparative genomics of 58 Legionella species

Intracellular parasitism, the driving force of evolution of Legionella pneumophila and the genus Legionella.

More than 18,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells.

How human pathogens may emerge from the environment

The pleotropic Legionella transcription factor LvbR links the Lqs and c-di-GMP regulatory networks to control biofilm architecture and virulence

Targeting of RNA Polymerase II by a nuclear Legionella pneumophila Dot/Icm effector SnpL.

Short genome report of cellulose-producing commensal Escherichia coli 1094.

Biological Diversity and Evolution of Type IV Secretion Systems

Rapid detection and evolutionary analysis of Legionella pneumophila serogroup 1 sequence type 47

Multiple major disease-associated clones of Legionella pneumophila have emerged recently and independently.

Molecular epidemiology, phylogeny and evolution of Legionella

Bacterial remodelling of the host epigenome: functional role and evolution of effectors methylating host histones

Biology Of Intracellular Bacteria

Comparative analyses of Legionella species identifies genetic features of strains causing Legionnaires’ disease

The Legionella pneumophila kai operon is implicated in stress response and confers fitness in competitive environments

Genome dynamics in Legionella: the basis of versatility and adaptation to intracellular replication.

Legionella pneumophila effector RomA uniquely modifies host chromatin to repress gene expression and promote intracellular bacterial replication

From amoeba to macrophages: exploring the molecular mechanisms of Legionella pneumophila infection in both hosts.

Characterization of an acetyltransferase that detoxifies aromatic chemicals in Legionella pneumophila.

Extensive recombination events and horizontal gene transfer shaped the Legionella pneumophila genomes.

Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions.

Specific real-time PCR for simultaneous detection and identification of Legionella pneumophila serogroup 1 in water and clinical samples.

Circadian clock proteins in prokaryotes: hidden rhythms?

The origins of eukaryotic-like proteins in Legionella pneumophila.

The Legionella pneumophila F-box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication

Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires’ disease.

Comparative sequence analysis of Mycobacterium leprae and the new leprosy-causing Mycobacterium lepromatosis.

Legionella pneumophila: population genetics, phylogeny and genomics.

Legionella pneumophila – Host Interactions: Insights Gained from Comparative Genomics and Cell Biology.

Molecular mimicry: an important virulence strategy employed by Legionella pneumophila to subvert host functions.

Patterns and rates of nucleotide substitution, insertion and deletion in the endosymbiont of ants Blochmannia floridanus.

Endosymbiont gene functions impaired and rescued by polymerase infidelity at poly(A) tracts.

Evolution of the secondary symbiont “Candidatus serratia symbiotica” in aphid species of the subfamily lachninae.

Reconstructing the ancestor of Mycobacterium leprae: the dynamics of gene loss and genome reduction.

Genome reduction of the aphid endosymbiont Buchnera aphidicola in a recent evolutionary time scale.

The evolutionary fate of nonfunctional DNA in the bacterial endosymbiont Buchnera aphidicola.

Coexistence of Wolbachia with Buchnera aphidicola and a secondary symbiont in the aphid Cinara cedri.

Molecular characterization of the leucine cluster in Buchnera sp. strain PSY, a primary endosymbiont of the aphid Pemphigus spyrothecae.