Timeline

Isabelle Staropoli

Research Engineer

24 Jan 2023

team

Antiviral Activities of Antibodies

17 Nov 2022

publication

Longitudinal analysis of serum neutralization of SARS-CoV-2 Omicron BA.2, BA.4, and BA.5 in patients receiving monoclonal antibodies.

05 Oct 2022

publication

Duration of BA.5 neutralization in sera and nasal swabs from SARS-CoV-2 vaccinated individuals, with or without omicron breakthrough infection.

01 Sep 2022

publication

Neutralising antibody responses to SARS-CoV-2 omicron among elderly nursing home residents following a booster dose of BNT162b2 vaccine: A community-based, prospective, longitudinal cohort study.

04 Jul 2022

publication

Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.

17 Jun 2022

news

New publication – Potent Human Broadly SARS-CoV-2 Neutralizing IgA and IgG Antibodies Effective Against Omicron BA.1 and BA.2

23 Mar 2022

publication

Serum neutralization of SARS-CoV-2 Omicron sublineages BA.1 and BA.2 in patients receiving monoclonal antibodies.

12 Mar 2022

publication

Fusogenicity and neutralization sensitivity of the SARS-CoV-2 Delta sublineage AY.4.2.

01 Feb 2022

publication

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization.

26 Jan 2022

publication

Low CCR5 expression protects HIV-specific CD4+ T cells of elite controllers from viral entry.

01 Nov 2021

publication

Release of infectious virus and cytokines in nasopharyngeal swabs from individuals infected with non-alpha or alpha SARS-CoV-2 variants: an observational retrospective study.

18 Aug 2021

news

Immune checkpoint inhibitors improve cellular immunity against SARS-CoV-2 infection

01 Aug 2021

publication

Immune checkpoint inhibitors increase T cell immunity during SARS-CoV-2 infection.

08 Jul 2021

publication

Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization.

18 May 2021

publication

Asymptomatic and symptomatic SARS-CoV-2 infections elicit polyfunctional antibodies.

01 Apr 2021

publication

SARS-CoV-2 infection in schools in a northern French city: a retrospective serological cohort study in an area of high transmission, France, January to April 2020.

01 Jan 2021

publication

Characteristics Associated with Olfactory and Taste Disorders in COVID-19.

02 Sep 2020

publication

A comparison of four serological assays for detecting anti-SARS-CoV-2 antibodies in human serum samples from different populations.

01 Sep 2020

publication

Serologic responses to SARS-CoV-2 infection among hospital staff with mild disease in eastern France.

06 Dec 2018

publication

CCR5 structural plasticity shapes HIV-1 phenotypic properties

22 Nov 2016

publication

Guidelines for cloning, expression, purification and functional characterization of primary HIV-1 envelope glycoproteins

16 Jul 2015

team

Group: Lisa Chakrabarti

03 Jul 2015

project

Viral Pathogenesis Unit’s Project

18 Jun 2015

publication

A single-residue change in the HIV-1 V3 loop associated with maraviroc resistance impairs CCR5 binding affinity while increasing replicative capacity

22 May 2014

publication

Targeting spare CC chemokine receptor 5 (CCR5) as a principle to inhibit HIV-1 entry

21 May 2013

publication

HIV-1 exploits CCR5 conformational heterogeneity to escape inhibition by chemokines

26 Jan 2012

publication

Mechanism of dengue virus broad cross-neutralization by a monoclonal antibody

30 Nov 2010

publication

New insights into the mechanisms whereby low molecular weight CCR5 ligands inhibit HIV-1 infection

02 Jul 2008

publication

The CXCL12gamma chemokine displays unprecedented structural and functional properties that make it a paradigm of chemoattractant proteins

01 Jan 2007

publication

The C type lectins DC-SIGN and L-SIGN: receptors for viral glycoproteins

01 Mar 2006

publication

Infection of dendritic cells (DCs), not DC-SIGN-mediated internalization of human immunodeficiency virus, is required for long-term transfer of virus to T cells

01 May 2005

publication

Differential maturation and subcellular localization of severe acute respiratory syndrome coronavirus surface proteins S, M and E

26 Apr 2005

publication

Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN)-mediated enhancement of dengue virus infection is independent of DC-SIGN internalization signals

10 Mar 2005

publication

Mutation of the DRY motif reveals different structural requirements for the CC chemokine receptor 5-mediated signaling and receptor endocytosis

27 Feb 2003

publication

DC-SIGN and L-SIGN are high affinity binding receptors for hepatitis C virus glycoprotein E2

22 Nov 2002

publication

Low levels of co-receptor CCR5 are sufficient to permit HIV envelope-mediated fusion with resting CD4 T cells

12 Nov 2002

publication

HIV-1 entry into T-cells is not dependent on CD4 and CCR5 localization to sphingolipid-enriched, detergent-resistant, raft membrane domains

26 Feb 2002

publication

Leukocyte elastase negatively regulates Stromal cell-derived factor-1 (SDF-1)/CXCR4 binding and functions by amino-terminal processing of SDF-1 and CXCR4

10 Nov 2000

publication

Processing, stability, and receptor binding properties of oligomeric envelope glycoprotein from a primary HIV-1 isolate

01 Dec 1997

publication

Affinity-purified dengue-2 virus envelope glycoprotein induces neutralizing antibodies and protective immunity in mice

01 Feb 1996

publication

Dengue virus envelope glycoprotein can be secreted from insect cells as a fusion with the maltose-binding protein

01 Jul 1994

publication

A little guide for advanced search:

Antiviral Activities of Antibodies

Longitudinal analysis of serum neutralization of SARS-CoV-2 Omicron BA.2, BA.4, and BA.5 in patients receiving monoclonal antibodies.

Duration of BA.5 neutralization in sera and nasal swabs from SARS-CoV-2 vaccinated individuals, with or without omicron breakthrough infection.

Neutralising antibody responses to SARS-CoV-2 omicron among elderly nursing home residents following a booster dose of BNT162b2 vaccine: A community-based, prospective, longitudinal cohort study.

Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.

New publication – Potent Human Broadly SARS-CoV-2 Neutralizing IgA and IgG Antibodies Effective Against Omicron BA.1 and BA.2

Serum neutralization of SARS-CoV-2 Omicron sublineages BA.1 and BA.2 in patients receiving monoclonal antibodies.

Fusogenicity and neutralization sensitivity of the SARS-CoV-2 Delta sublineage AY.4.2.

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization.

Low CCR5 expression protects HIV-specific CD4+ T cells of elite controllers from viral entry.

Release of infectious virus and cytokines in nasopharyngeal swabs from individuals infected with non-alpha or alpha SARS-CoV-2 variants: an observational retrospective study.

Immune checkpoint inhibitors improve cellular immunity against SARS-CoV-2 infection

Immune checkpoint inhibitors increase T cell immunity during SARS-CoV-2 infection.

Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization.

Asymptomatic and symptomatic SARS-CoV-2 infections elicit polyfunctional antibodies.

SARS-CoV-2 infection in schools in a northern French city: a retrospective serological cohort study in an area of high transmission, France, January to April 2020.

Characteristics Associated with Olfactory and Taste Disorders in COVID-19.

A comparison of four serological assays for detecting anti-SARS-CoV-2 antibodies in human serum samples from different populations.

Serologic responses to SARS-CoV-2 infection among hospital staff with mild disease in eastern France.

CCR5 structural plasticity shapes HIV-1 phenotypic properties

Guidelines for cloning, expression, purification and functional characterization of primary HIV-1 envelope glycoproteins

Group: Lisa Chakrabarti

Viral Pathogenesis Unit’s Project

A single-residue change in the HIV-1 V3 loop associated with maraviroc resistance impairs CCR5 binding affinity while increasing replicative capacity

Targeting spare CC chemokine receptor 5 (CCR5) as a principle to inhibit HIV-1 entry

HIV-1 exploits CCR5 conformational heterogeneity to escape inhibition by chemokines

Mechanism of dengue virus broad cross-neutralization by a monoclonal antibody

New insights into the mechanisms whereby low molecular weight CCR5 ligands inhibit HIV-1 infection

The CXCL12gamma chemokine displays unprecedented structural and functional properties that make it a paradigm of chemoattractant proteins

The C type lectins DC-SIGN and L-SIGN: receptors for viral glycoproteins

Infection of dendritic cells (DCs), not DC-SIGN-mediated internalization of human immunodeficiency virus, is required for long-term transfer of virus to T cells

Differential maturation and subcellular localization of severe acute respiratory syndrome coronavirus surface proteins S, M and E

Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN)-mediated enhancement of dengue virus infection is independent of DC-SIGN internalization signals

Mutation of the DRY motif reveals different structural requirements for the CC chemokine receptor 5-mediated signaling and receptor endocytosis

DC-SIGN and L-SIGN are high affinity binding receptors for hepatitis C virus glycoprotein E2

Low levels of co-receptor CCR5 are sufficient to permit HIV envelope-mediated fusion with resting CD4 T cells

HIV-1 entry into T-cells is not dependent on CD4 and CCR5 localization to sphingolipid-enriched, detergent-resistant, raft membrane domains

Leukocyte elastase negatively regulates Stromal cell-derived factor-1 (SDF-1)/CXCR4 binding and functions by amino-terminal processing of SDF-1 and CXCR4

Processing, stability, and receptor binding properties of oligomeric envelope glycoprotein from a primary HIV-1 isolate

Affinity-purified dengue-2 virus envelope glycoprotein induces neutralizing antibodies and protective immunity in mice

Dengue virus envelope glycoprotein can be secreted from insect cells as a fusion with the maltose-binding protein

Analysis of C-terminally truncated dengue 2 and dengue 3 virus envelope glycoproteins: processing in insect cells and immunogenic properties in mice