It is now clear that immune cells, classically known for their role in fighting infection, play key roles in brain development, homeostasis, and disease. Our lab is interested in better understanding the interactions between immune cells and the brain, and the role of these communication circuits in shaping brain function in physiology, aging and disease. Our approach encompasses scRNA-seq and other technologies of genomics, classical tools of immunology, neuroscience, and everything else that could help us identify the mechanisms of brain-immune communication.
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Former Members
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Name
Position
2022
2022
SAENZ Daniel
undergraduate student
2022
2022
FAYAD Ariane
undergraduate student
2022
2022
LAMBERT Kyle
undergraduate student
2022
2022
SINGH Roshani
graduate student
2022
2022
NINOU Elpiniki
visiting scientist
2022
2023
MOURGUE D'ALGUE Laure
graduate student
2023
2023
ALVAREZ PUGA Martin
undergraduate student
2022
2023
DREW Simon
Scientist
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Projects
Transversal Project
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Publications
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2023Chelator PBT2 Forms a Ternary Cu2+ Complex with β-Amyloid That Has High Stability but Low Specificity., Int J Mol Sci 2023 May; 24(11): .
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2023Bacterial capsular polysaccharides with antibiofilm activity share common biophysical and electrokinetic properties., Nat Commun 2023 May; 14(1): 2553.
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2022Microbial and immune factors regulate brain maintenance and aging., Curr Opin Neurobiol 2022 Jul; 76(): 102607.
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2022The interaction of CD4+ helper T cells with dendritic cells shapes the tumor microenvironment and immune checkpoint blockade response., Nat Cancer 2022 03; 3(3): 303-317.
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2022Isolation and Characterization of the Immune Cells from Micro-dissected Mouse Choroid Plexuses, JoVE J. 2022 ().
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2021XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis., Nat Med 2021 May; (): .
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2021NASH limits anti-tumour surveillance in immunotherapy-treated HCC., Nature 2021 Apr; 592(7854): 450-456.
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2021Meningeal lymphoid structures are activated under acute and chronic spinal cord pathologies., Life Sci Alliance 2021 Jan; 4(1): .
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2020Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients., Cell 2020 Jun; 181(7): 1475-1488.e12.
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2019Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner., Cell 2019 Jul; 178(3): 686-698.e14.
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