Immune activity at the brain borders
Immune cells modulate CNS activities in physiology, but peripheral immune cells are rarely found in direct contact with the neural tissue. Instead, the immune cells are thought to affect the brain remotely and indirectly, […]
Microglia are extremely specialized immune cells, which reside in the CNS and play key roles in its development, homeostasis and disease. Such specialization is imposed by the peculiar environment the microglia have to live […]
2022Microbial and immune factors regulate brain maintenance and aging., Curr Opin Neurobiol 2022 Jul; 76(): 102607.
2022Isolation and Characterization of the Immune Cells from Micro-dissected Mouse Choroid Plexuses, JoVE J. 2022 ().
2021XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis., Nat Med 2021 May; (): .
2020The Physiology, Pathology, and Potential Therapeutic Applications of the TREM2 Signaling Pathway., Cell 2020 06; 181(6): 1207-1217.
2018Targeting neuro-immune communication in neurodegeneration: Challenges and opportunities., J Exp Med 2018 11; 215(11): 2702-2704.
2018Microglial immune checkpoint mechanisms., Nat Neurosci 2018 06; 21(6): 779-786.
2018Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration., Cell 2018 05; 173(5): 1073-1081.