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  • whocc
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  • tool
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  • Associate Professor
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  • Clinical Research Nurse
  • Clinician Researcher
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  • Dual-education Student
  • Full Professor
  • Honorary Professor
  • Lab assistant
  • Master Student
  • Non-permanent Researcher
  • Nursing Staff
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Prize
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
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Scientific Fields
Diseases
Organisms
Applications
Technique

About

 

Peripheral immune cells  modulate brain activities in physiology, but they are rarely found in direct contact with the neural tissue. Similarly, microbial products can shape brain development and aging, yet no commensal bacteria are found in healthy brain.  We hypothesize that such peripheral immune and microbial signals affect the brain remotely and indirectly, from its borders, anatomical structures, which separate the central nervous system from the periphery. We aim to identify mechanisms of such remote immune and microbial influence on the brain by focusing on the choroid plexus (blood-CSF barrier) and the skull marrow niche in the context of brain development, aging and disease. 

Former Members

2000
2000
Name
Position
2022
2022
SAENZ Daniel
undergraduate student
2022
2022
FAYAD Ariane
undergraduate student
2022
2022
LAMBERT Kyle
undergraduate student
2022
2022
SINGH Roshani
graduate student
2022
2022
NINOU Elpiniki
visiting scientist
2022
2023
MOURGUE D'ALGUE Laure
graduate student
2023
2023
ALVAREZ PUGA Martin
undergraduate student
2022
2023
DREW Simon
Scientist
2023
2024
PINCON Annaelle
graduate student
2024
2024
SARROU Emeric
undergraduate student
2023
2024
BASURCO-GOGRENA Leyre
post doc - visiting scientist
2023
2024
PEDONE Rubia
graduate student
2023
2024
MAIER Benjamin
Physician
Show all

Projects

Project
Ongoing
3 Members

Étude de la réponse inflammatoire médiée par les polynucléaires neutrophiles au cours des accidents vasculaires cérébraux : NEUTROBLOOD (2023-037)

Aleksandra Deczkowska (PI)

Sorry, this entry is only available in FR.
Project
Ongoing
2 Members

Microglial checkpoints

Aleksandra Deczkowska (PI)

Microglia are extremely specialized immune cells, which reside in the CNS and play key roles in its development, homeostasis and disease. Such specialization is imposed by the peculiar environment the microglia have to live […]

Transversal Project

Drug Discovery & Screening at Institut Pasteur

The Technological Targeted Action Drug Discovery and Screening (ATC-DDS) coordinates projects and collaborations at the Institut Pasteur Paris campus on therapeutic development. It raises awareness for DDS in basic research projects and stimulates intra-campus […]

Brain connectivity and neurodegenerative diseases

The brain is a complex organ, and its well-being depends on the harmonic interactions with the rest of our body. Nearly all brain disorders manifest themselves in the dysfunction of communication between brain cells […]

Fundings

Publications

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