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Content 2

Content Type

member
team
department
center
program_project
nrc
whocc
project
software
tool
patent

Keywords

Positions

Administrative Staff
Assistant Professor
Associate Professor
Clinical Research Assistant
Clinical Research Nurse
Clinician Researcher
Department Manager
Dual-education Student
Full Professor
Honorary Professor
Lab assistant
Master Student
Non-permanent Researcher
Nursing Staff
Permanent Researcher
Pharmacist
PhD Student
Physician
Post-doc
Prize
Project Manager
Research Associate
Research Engineer
Retired scientist
Technician
Undergraduate Student
Veterinary
Visiting Scientist

Appointments

Deputy Director of Center
Deputy Director of Department
Deputy Director of National Reference Center
Deputy Head of Facility
Director of Center
Director of Department
Director of Institute
Director of National Reference Center
Group Leader
Head of Facility
Head of Operations
Head of Structure
Honorary President of the Departement
Labex Coordinator

Search

SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction.

Nucleic acids research

Lavigne M, Helynck O, Rigolet P, Boudria-Souilah R, Nowakowski M, Baron B, Brülé S, Hoos S, Raynal B, Guittat L, Beauvineau C, Petres S, Granzhan A, Guillon J, Pratviel G, Teulade-Fichou MP, England P, Mergny JL, Munier-Lehmann H

An Attractive Reelin Gradient Establishes Synaptic Lamination in the Vertebrate Visual System

Neuron

Vincenzo Di Donato, Flavia De Santis, Shahad Albadri, Thomas Oliver Auer, Karine Duroure, Marine Charpentier, Jean-Paul Concordet, Christoph Gebhardt, and Filippo Del Bene

Single-Molecule Analysis of mtDNA Replication Uncovers the Basis of the Common Deletion

Molecular cell

Phillips AF, Millet AR, Tigano M, Dubois SM, Crimmins H, Babin L, Charpentier M, Piganeau M, Brunet E, Sfeir A

Argonaute proteins regulate HIV-1 multiply spliced RNA and viral production in a Dicer independent manner

Nucleic acids research

Eckenfelder A, Ségéral E, Pinzón N, Ulveling D, Amadori C, Charpentier M, Nidelet S, Concordet JP, Zagury JF, Paillart JC, Berlioz-Torrent C, Seitz H, Emiliani S, Gallois-Montbrun S

Near-complete elimination of mutant mtDNA by iterative or dynamic dose-controlled treatment with mtZFNs

Nucleic acids research

Gammage PA, Gaude E, Van Haute L, Rebelo-Guiomar P, Jackson CB, Rorbach J, Pekalski ML, Robinson AJ, Charpentier M, Concordet JP, Frezza C, Minczuk M

CSF-contacting neurons regulate locomotion by relaying mechanical stimuli to spinal circuits

Nature communications

Böhm UL, Prendergast A, Djenoune L, Nunes Figueiredo S, Gomez J, Stokes C, Kaiser S, Suster M, Kawakami K, Charpentier M, Concordet JP, Rio JP, Del Bene F, Wyart C

Improved Genome Editing Efficiency and Flexibility Using Modified Oligonucleotides with TALEN and CRISPR-Cas9 Nucleases

Cell reports

Renaud JB, Boix C, Charpentier M, De Cian A, Cochennec J, Duvernois-Berthet E, Perrouault L, Tesson L, Edouard J, Thinard R, Cherifi Y, Menoret S, Fontanière S, de Crozé N, Fraichard A, Sohm F, Anegon I, Concordet JP, Giovannangeli C

Large Scale Active-Learning-Guided Exploration for in Vitro Protein Production Optimization

Nature Communications

Olivier Borkowski, Mathilde Koch, Agnès Zettor, Amir Pandi, Angelo Cardoso Batista, Paul Soudier, Jean-Loup Faulon

High Content Screening Assay of Inhibitors of the Legionella pneumophila Histone Methyltransferase RomA in Infected Cells.

Chembiochem : a European journal of chemical biology

Barbachowska M, Harviel T, Nicchi S, Danckaert A, Ghazarian M, Chiaravalli J, Buchrieser C, Rolando M, Arimondo P

Osteopontin in the host response to Leishmania amazonensis.

BMC microbiology

Giraud E, Rouault E, Fiette L, Colle JH, Smirlis D, Melanitou E

Structure, function, and evolution of the Orthobunyavirus membrane fusion glycoprotein.

Cell reports

Hellert J, Aebischer A, Haouz A, Guardado-Calvo P, Reiche S, Beer M, Rey FA

Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants.

Nature communications

de Melo GD, Perraud V, Alvarez F, Vieites-Prado A, Kim S, Kergoat L, Coleon A, Trüeb BS, Tichit M, Piazza A, Thierry A, Hardy D, Wolff N, Munier S, Koszul R, Simon-Lorière E, Thiel V, Lecuit M, Lledo PM, Renier N, Larrous F, Bourhy H

SARS-CoV-2 variant prediction and antiviral drug design are enabled by RBD in vitro evolution.

Nature microbiology

Zahradník J, Marciano S, Shemesh M, Zoler E, Harari D, Chiaravalli J, Meyer B, Rudich Y, Li C, Marton I, Dym O, Elad N, Lewis MG, Andersen H, Gagne M, Seder RA, Douek DC, Schreiber G,

Qualitative monitoring of SARS-CoV-2 mRNA vaccination in humans using droplet microfluidics.

JCI insight

Broketa M, Sokal A, Mor M, Canales-Herrerias P, Perima A, Meola A, Fernández I, Iannascoli B, Chenon G, Vandenberghe A, Languille L, Michel M, Godeau B, Gallien S, Melica G, Backovic M, Rey FA, Baudry J, Freund NT, Mahévas M, Bruhns P

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Characterization of TelE, a T7SS LXG Effector Exhibiting a Conserved C-Terminal Glycine Zipper Motif Required for Toxicity.

Anti-V1/V3-glycan broadly HIV-1 neutralizing antibodies in a post-treatment controller.

Calls

INCEPTION- Call for Workshop/Visiting Scientist

Events

20 Upcoming Events

Calendar

Today

06 Oct 2024

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DBSC Seminar – Damien Ekiert – Bridges, Tunnels, and Ferries: How bacteria transport lipids between membranes

Production and Purification of Recombinant Proteins Technological Platform

Molecular Biophysics

Group: Biochemistry and chemobiology

UMR3523 – Chemistry for Life Sciences (Chem4Life)

Chemogenomic and Biological Screening Platform (PF-CCB)

Olivier Helynck

Mireille Nowakowski

Sébastien Brûlé

Bertrand Raynal

Stéphane Petres

Patrick England

Hélène Munier-Lehmann

Workshop of The Structural Bioinformatics Unit

Production and Purification of Recombinant Proteins Technological Platform

Molecular Biophysics

Group: Biochemistry and chemobiology

UMR3523 – Chemistry for Life Sciences (Chem4Life)

Chemogenomic and Biological Screening Platform (PF-CCB)

Olivier Helynck

Mireille Nowakowski

Sébastien Brûlé

Bertrand Raynal

Stéphane Petres

Patrick England

Hélène Munier-Lehmann

LabEx Milieu Intérieur Annual Meeting 2024

Production and Purification of Recombinant Proteins Technological Platform

Molecular Biophysics

Group: Biochemistry and chemobiology

UMR3523 – Chemistry for Life Sciences (Chem4Life)

Chemogenomic and Biological Screening Platform (PF-CCB)

Olivier Helynck

Mireille Nowakowski

Sébastien Brûlé

Bertrand Raynal

Stéphane Petres

Patrick England

Hélène Munier-Lehmann

Seminar Dept Neuroscience “Combinatorial Creatures: Cortical plasticity within and across lifetimes.” – Leah Krubitzer

Production and Purification of Recombinant Proteins Technological Platform

Molecular Biophysics

Group: Biochemistry and chemobiology

UMR3523 – Chemistry for Life Sciences (Chem4Life)

Chemogenomic and Biological Screening Platform (PF-CCB)

Olivier Helynck

Mireille Nowakowski

Sébastien Brûlé

Bertrand Raynal

Stéphane Petres

Patrick England

Hélène Munier-Lehmann

Seminar Dept Microbiology “tRNA queuosine modification, a general regulatory mechanism controlling biofilm formation, resistance and virulence in bacteria” – José Eduardo González-Pastor

Production and Purification of Recombinant Proteins Technological Platform

Molecular Biophysics

Group: Biochemistry and chemobiology

UMR3523 – Chemistry for Life Sciences (Chem4Life)

Chemogenomic and Biological Screening Platform (PF-CCB)

Olivier Helynck

Mireille Nowakowski

Sébastien Brûlé

Bertrand Raynal

Stéphane Petres

Patrick England

Hélène Munier-Lehmann

Meeting in memory of Gérard Orth, a visionary (1936-2023)

Production and Purification of Recombinant Proteins Technological Platform

Molecular Biophysics

Group: Biochemistry and chemobiology

UMR3523 – Chemistry for Life Sciences (Chem4Life)

Chemogenomic and Biological Screening Platform (PF-CCB)

Olivier Helynck

Mireille Nowakowski

Sébastien Brûlé

Bertrand Raynal

Stéphane Petres

Patrick England

Hélène Munier-Lehmann

Jobs

Job: PhD Student

PPU PhD program Call 2024-2025

Cochlear development and therapeutic perspectives

Postdoc position to develop novel anti-leishmanial treatment using nanobody engineering

Signalling and host-parasite interactions

Funded postdoctoral position in the Lecuit lab at Institut Pasteur

Biology of infection

Job: Master Student

M2 Internship: Is the sex-ratio dynamic in Asthma throughout life driven by sex-hormones?

Statistical Genetics

Network

Publications

A wave of bipotent T/ILC-restricted progenitors shapes the embryonic thymus microenvironment in a time-dependent manner.

Megasatellite formation and evolution in vertebrate genes.

One health (Amsterdam, Netherlands)

Drivers of ESBL-producing Escherichia coli dynamics in calf fattening farms: A modelling study.

Nature communications

Ageing affects DNA methylation drift and transcriptional cell-to-cell variability in mouse muscle stem cells.

News

3rd France – Japan symposium on HIV/AIDS & Infectious diseases basic research

New publication – The Nicotinic Acetylcholine Receptor and its Pentameric Homolog...

ISBI 2024 award !

A new G5 research group in the Department of Microbiology