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member
team
department
center
program_project
nrc
whocc
project
software
tool
patent

Keywords

Positions

Administrative Staff
Assistant Professor
Associate Professor
Clinical Research Assistant
Clinical Research Nurse
Clinician Researcher
Department Manager
Dual-education Student
Full Professor
Honorary Professor
Lab assistant
Master Student
MD-PhD Student
Medical Staff
Non-permanent Researcher
Nursing Staff
Permanent Researcher
Pharmacist
PhD Student
Physician
Post-doc
Prize
Project Manager
Research Associate
Research Engineer
Retired scientist
Technician
Undergraduate Student
Veterinary
Visiting Scientist

Appointments

Deputy Director of Center
Deputy Director of Department
Deputy Director of National Reference Center
Deputy Head of Facility
Director of Center
Director of Department
Director of Institute
Director of National Reference Center
Group Leader
Head of Facility
Head of Operations
Head of Structure
Honorary President of the Departement
Labex Coordinator

Search

Use of fluorescence spectroscopy for quantitative investigations of ubiquitin interactions with the ubiquitin-binding domains of NEMO

Methods in molecular biology (Clifton, N.J.)

Dubosclard V, Fontan E, Agou F

Two-sided ubiquitin binding of NF-κB essential modulator (NEMO) zinc finger unveiled by a mutation associated with anhidrotic ectodermal dysplasia with immunodeficiency syndrome

The Journal of biological chemistry

Ngadjeua F, Chiaravalli J, Traincard F, Raynal B, Fontan E, Agou F

Two NEMO-like Ubiquitin-Binding Domains in CEP55 Differently Regulate Cytokinesis.

iScience

Said Halidi KN, Fontan E, Boucharlat A, Davignon L, Charpentier M, Boullé M, Weil R, Israël A, Laplantine E, Agou F.

Design and synthesis of naturally-inspired SARS-CoV-2 inhibitors.

RSC medicinal chemistry

Hassan H, Chiavaralli J, Hassan A, Bedda L, Krischuns T, Chen KY, Li ASM, Delpal A, Decroly E, Vedadi M, Naffakh N, Agou F, Mallart S, Arafa RK, Arimondo PB,

A sensitive fluorescence-based assay to monitor enzymatic activity of the essential integral membrane protein Apolipoprotein N-acyltransferase (Lnt)

Scientific Reports

Karine Nozeret, Alix Boucharlat, Fabrice Agou, Nienke Buddelmeijer

Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential.

Nature communications

Meyer B, Chiaravalli J, Gellenoncourt S, Brownridge P, Bryne DP, Daly LA, Grauslys A, Walter M, Agou F, Chakrabarti LA, Craik CS, Eyers CE, Eyers PA, Gambin Y, Jones AR, Sierecki E, Verdin E, Vignuzzi M, Emmott E,

DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding

Journal of molecular biology

Grubisha O, Kaminska M, Duquerroy S, Fontan E, Cordier F, Haouz A, Raynal B, Chiaravalli J, Delepierre M, Israël A, Véron M, Agou F

Enhanced neutralization escape to therapeutic monoclonal antibodies by SARS-CoV-2 omicron sub-lineages.

iScience

Touret F, Giraud E, Bourret J, Donati F, Tran-Rajau J, Chiaravalli J, Lemoine F, Agou F, Simon-Lorière E, van der Werf S, de Lamballerie X

Novel mutations involving the INSL3 gene associated with cryptorchidism

The Journal of urology

El Houate B, Rouba H, Sibai H, Barakat A, Chafik A, Chadli el B, Imken L, Bogatcheva NV, Feng S, Agoulnik AI, McElreavey K

Mutations of the GREAT gene cause cryptorchidism

Human molecular genetics

Gorlov IP, Kamat A, Bogatcheva NV, Jones E, Lamb DJ, Truong A, Bishop CE, McElreavey K, Agoulnik AI

[Elucidating and characterizing the dynamic biological processes that account for the sustainability of Leishmania populations].

Medecine tropicale et sante internationale

Giraud É, Milon G

Plate washer and dispenser • Biotek • EL406

Chemogenomic and Biological Screening Platform (PF-CCB)

Multimodal Plate Reader • Tecan • Spark

Chemogenomic and Biological Screening Platform (PF-CCB)

An original infection model identifies host lipoprotein import as a route for blood-brain barrier crossing.

Nature communications

Benmimoun B, Papastefanaki F, Périchon B, Segklia K, Roby N, Miriagou V, Schmitt C, Dramsi S, Matsas R, Spéder P,

Viaflo • Integra Biosciences • Viaflo 96 & 384

Chemogenomic and Biological Screening Platform (PF-CCB)

qPCR instrument • BioRad • CFX96

Chemogenomic and Biological Screening Platform (PF-CCB)

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Events

17 Upcoming Events

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13 Jun 2025

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IBEID Labex Day 25

Chemogenomic and Biological Screening Platform (PF-CCB)

UMR3523 – Chemistry for Life Sciences (Chem4Life)

Table ronde virtuelle ERC

Chemogenomic and Biological Screening Platform (PF-CCB)

UMR3523 – Chemistry for Life Sciences (Chem4Life)

Joint seminar Département des Parasites et Insectes Vecteurs – Département Microbiologie : Mathilde GENDRIN “Deciphering positive and negative impacts of bacteria on mosquito life cycle”

Chemogenomic and Biological Screening Platform (PF-CCB)

UMR3523 – Chemistry for Life Sciences (Chem4Life)

“Mother & Child Health” Seminar: Stress-responsive pathways in pathophysiological prenatal brain development – Valérie MEZGER

Chemogenomic and Biological Screening Platform (PF-CCB)

UMR3523 – Chemistry for Life Sciences (Chem4Life)

Department of Parasites and Insect Vectors Seminar : Professor Hedda Wardemann “Rational design of a novel CSP-based Plasmodium falciparum malaria vaccine”

Chemogenomic and Biological Screening Platform (PF-CCB)

UMR3523 – Chemistry for Life Sciences (Chem4Life)

CVI Workshop Series – Malaria – Chetan Chitnis, Rogerio Amino, Michael White, Anne-Sophie Beignon

Chemogenomic and Biological Screening Platform (PF-CCB)

UMR3523 – Chemistry for Life Sciences (Chem4Life)

Jobs

Job: Project Manager

Project manager: Genomic taxonomy of bacterial strains, epidemiological surveillance and antimicrobial resistance

Biodiversity and Epidemiology of Bacterial Pathogens

Job: Master Student

M2 internship in Cancer Immunology and Immunotherapy

Center for Vaccinology and Immunotherapy (CVI)

Job: Master Student

M2 internship in vaccines and immunology

Post-doctoral positionCell biology/ Epigenetics

Cellular Biology of Microbial Infection

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Publications

Infection Reveals a Modification of SIRT2 Critical for Chromatin Association.

Antioxidants & redox signaling

Reactive Species in Progeroid Syndromes and Aging-Related Processes.

Nature genetics

Dynamic interplay between enhancer-promoter topology and gene activity

PLoS computational biology

Close proximity interactions support transmission of ESBL-K. pneumoniae but not ESBL-E. coli in healthcare settings

News

Press coverage of Lopopolo et al. 2025 Science

Summary of our scientific contributions to the 2005-06 chikungunya outbreak

The Spread of Antibiotic Resistance Is Driven by Plasmids Among the Fastest Evolving an...

Adaptive genomic plasticity in large-genome, broad-host-range vibrio phages