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member
team
department
center
program_project
nrc
whocc
project
software
tool
patent

Keywords

Positions

Administrative Staff
Assistant Professor
Associate Professor
Clinical Research Assistant
Clinical Research Nurse
Clinician Researcher
Department Manager
Dual-education Student
Full Professor
Honorary Professor
Lab assistant
Master Student
MD-PhD Student
Medical Staff
Non-permanent Researcher
Nursing Staff
Permanent Researcher
Pharmacist
PhD Student
Physician
Post-doc
Prize
Project Manager
Research Associate
Research Engineer
Retired scientist
Technician
Undergraduate Student
Veterinary
Visiting Scientist

Appointments

Deputy Director of Center
Deputy Director of Department
Deputy Director of National Reference Center
Deputy Head of Facility
Director of Center
Director of Department
Director of Institute
Director of National Reference Center
Group Leader
Head of Facility
Head of Operations
Head of Structure
Honorary President of the Departement
Labex Coordinator

Search

qPCR instrument • Applied Biosystems • Quantstudio 6 Pro

Chemogenomic and Biological Screening Platform (PF-CCB)

Grating Coupled Interferometry • Malvern • Creoptix WAVEcore

Chemogenomic and Biological Screening Platform (PF-CCB)

Microscope • Optical Biosystems • StellarVision

Chemogenomic and Biological Screening Platform (PF-CCB)

Microscope • Olympus • IX83

Chemogenomic and Biological Screening Platform (PF-CCB)

Tycho • Nanotemper • NT.6

Chemogenomic and Biological Screening Platform (PF-CCB)

Echo Liquid Handler System • Labcyte • Echo 550

Chemogenomic and Biological Screening Platform (PF-CCB)

Direct inhibition of NF-κB activation by peptide targeting the NOA ubiquitin binding domain of NEMO

Biochemical pharmacology

Chiaravalli J, Fontan E, Fsihi H, Coic YM, Baleux F, Véron M, Agou F

Natural variation can significantly alter the sensitivity of influenza A (H5N1) viruses to oseltamivir.

Antimicrobial agents and chemotherapy

Rameix-Welti MA, Agou F, Buchy P, Mardy S, Aubin JT, Véron M, van der Werf S, Naffakh N,

Greater diversity of HIV DNA variants in the rectum compared to variants in the blood in patients without HAART.

Journal of medical virology

Avettand-Fenoel V, Hocqueloux L, Müller-Trutwin M, Prazuck T, Melard A, Chaix ML, Agoute E, Michau C, Rouzioux C,

Design, synthesis, biophysical and biological evaluation of original condensed pyrrolopyrimidine and pyrrolopyridine ligands as anti-SARS-CoV-2 agents targeting G4

European Journal of Medicinal Chemistry

Jean Guillon, Solène Savrimoutou, Nicolas da Rocha, Sandra Albenque-Rubio, Olivier Helynck, Cyrielle Durand, Jeanne Chiaravalli, Noël Pinaud, Luisa Ronga, Stéphane Moreau, Simon Chirold, Tshering Zangmo, Melika Arab, Lindita Lari, Jean‐louis Mergny, Hélène Munier-Lehmann, Marc Lavigne

TALEN-Induced Double-Strand Break Repair of CTG Trinucleotide Repeats.

Cell Report

Valentine Mosbach, Lucie Poggi, David Viterbo, Marine Charpentier and Guy-Franck Richard

Small-molecule inhibition of Lats kinases may promote Yap-dependent proliferation in postmitotic mammalian tissues.

Nature communications

Kastan N, Gnedeva K, Alisch T, Petelski AA, Huggins DJ, Chiaravalli J, Aharanov A, Shakked A, Tzahor E, Nagiel A, Segil N, Hudspeth AJ,

Intracellular growth of Mycobacterium tuberculosis after macrophage cell death leads to serial killing of host cells.

Elife

Mahamed D, Boulle M, Ganga Y, Mc Arthur C, Skroch S, Oom L, Catinas O, Pillay K, Naicker M, Rampersad S, Mathonsi C, Hunter J, Wong EB, Suleman M, Sreejit G, Pym AS, Lustig G, Sigal A

CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair.

Nature Communications

Charpentier M, Khedher AHY, Menoret S, Brion A, Lamribet K, Dardillac E, Boix C, Perrouault L, Tesson L, Geny S, De Cian A, Itier JM, Anegon I, Lopez B, Giovannangeli C and Concordet JP

HIV Cell-to-Cell Spread Results in Earlier Onset of Viral Gene Expression by Multiple Infections per Cell

PLoS Pathogens

Boullé M, Müller TG, Dähling S, Ganga Y, Jackson L, Mahamed D, Oom L, Lustig G, Neher RA, Sigal A

Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMPDHs.

Protein science : a publication of the Protein Society

Gedeon A, Ayoub N, Brûlé S, Raynal B, Karimova G, Gelin M, Mechaly A, Haouz A, Labesse G, Munier-Lehmann H

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Higher convergence of human-great ape enteric eukaryotic viromes in central African forest than in a European zoo: a One Health analysis.

Successful treatment of JAK1-associated inflammatory disease.

Calls

INCEPTION- Call for Workshop/Visiting Scientist

Events

7 Upcoming Events

Calendar

Today

13 Jul 2025

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ClostPath 2025

Chemogenomic and Biological Screening Platform (PF-CCB)

Chemogenomic and Biological Screening Platform (PF-CCB)

Biology of Host-Parasite Interactions Legacy Symposium – Pierre Buffet, Luísa Figueiredo, Benoît Gamain, Julien Guizetti, Mohamed-Ali Hakimi, Jose-Juan Lopez-Rubio, Marta Nunes, Stuart Ralph, David Roos, Nicolai Siegel, Shruthi Vembar, Till Voss

Chemogenomic and Biological Screening Platform (PF-CCB)

Gastrulation Reloaded – Developing, engineering and evolving the body plan

Chemogenomic and Biological Screening Platform (PF-CCB)

“Mother and Child Health Program – Seminar”: Sex-specific physiological trade-offs during juvenile protein malnutrition – François LEULIER

Chemogenomic and Biological Screening Platform (PF-CCB)

EFIS Sex Differences in Immunity Congress

Chemogenomic and Biological Screening Platform (PF-CCB)

Jobs

Job: Project Manager

Project manager: Genomic taxonomy of bacterial strains, epidemiological surveillance and antimicrobial resistance

Biodiversity and Epidemiology of Bacterial Pathogens

Job: Master Student

M2 internship in Cancer Immunology and Immunotherapy

Center for Vaccinology and Immunotherapy (CVI)

Job: Master Student

M2 internship in vaccines and immunology

Post-doctoral positionCell biology/ Epigenetics

Cellular Biology of Microbial Infection

Network

Publications

Nature immunology

Inflammation triggers ILC3 patrolling of the intestinal barrier.

EMBO Molecular Medicine

CIB2, defective in isolated deafness, is key for auditory hair cell mechanotransduction and survival

Nature communications

Legionella para-effectors target chromatin and promote bacterial replication.

Cell host & microbe

Manipulating Mosquito Tolerance for Arbovirus Control.

News

ALLOSTERY TURNS 60: celebration with Changeux lui-même

Scientific mediation of Lopopolo et al. 2025 Science

Summary of our scientific contributions to the 2005-06 chikungunya outbreak

The Spread of Antibiotic Resistance Is Driven by Plasmids Among the Fastest Evolving an...