Link to Pubmed [PMID] – 27884799
Link to DOI – S1286-4579(16)30171-X10.1016/j.micinf.2016.10.011
Microbes Infect 2017 Mar; 19(3): 157-165
Hypoxia is defined as a tissue oxygenation status below physiological needs. During Shigella infection, an infectious hypoxia is induced within foci of infection. In this review, we discuss how Shigella physiology and virulence are modulated and how the main recruited immune cells, the neutrophils, adapt to this environment.