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© William Beaucardet
Reportage Unité Intéractions bactéries cellules
Publication : Human vaccines

Antibodies to tetanus, diphtheria and pertussis among healthy adults vaccinated according to the French vaccination recommendations

Team: Clinical Investigation Platform ICAReB-Clin
Member: Marie-Noelle Ungeheuer
Member: Elisabeth Njamkepo Nguemkam
Member: Didier Guillemot
Member: Nicole Guiso
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Human vaccines - 09 May 2009

Launay O, Toneatti C, Bernède C, Njamkepo E, Petitprez K, Leblond A, Larnaudie S, Goujon C, Ungeheuer MN, Ajana F, Raccurt C, Beytout J, Chidiac C, Bouhour D, Guillemot D, Guiso N

Link to Pubmed [PMID] – 19221513

Hum Vaccin 2009 May;5(5):341-6

In this sero-epidemiological study, we investigated humoral immunity to three vaccine-preventable diseases–tetanus, diphtheria and pertussis–among 331 adults (aged 18-60 years) attending vaccination centres for travellers and who had been vaccinated according to national recommendations in France. Serological results showed that the percentage of subjects with antibodies to diphtheria and tetanus decreases with age. Results also confirmed surveillance data on vaccination in France, with 7.6% of the study population (13.4% of those aged 18-29 years) having recently acquired a pertussis infection. These results confirm the importance of following French recommendations for regular boosters for tetanus and diphtheria among adults. They also indicate the need for better implementation of the current recommendations for pertussis-vaccine boosters in adults.