• 2020
  Géléoc GGS, El-Amraoui A, , Disease mechanisms and gene therapy for Usher syndrome., Hear. Res. 2020 Sep; 394(): 107932.
• 2020
  Delmaghani S, El-Amraoui A, , Inner Ear Gene Therapies Take Off: Current Promises and Future Challenges., J Clin Med 2020 Jul; 9(7): .
• 2020
  Charfeddine C, Dallali H, Abdessalem G, Ghedira K, Hamdi Y, Elouej S, Landoulsi Z, Delague V, Lagarde A, Levy N, El-Amraoui A, Boubaker MS, Abdelhak S, Mokni M, , Identification of a CDH12 potential candidate genetic variant for an autosomal dominant form of transgrediens and progrediens palmoplantar keratoderma in a Tunisian family., J. Hum. Genet. 2020 Apr; 65(4): 397-410.
• 2019
  Dunbar LA, Patni P, Aguilar C, Mburu P, Corns L, Wells HR, Delmaghani S, Parker A, Johnson S, Williams D, Esapa CT, Simon MM, Chessum L, Newton S, Dorning J, Jeyarajan P, Morse S, Lelli A, Codner GF, Peineau T, Gopal SR, Alagramam KN, Hertzano R, Dulon D, Wells S, Williams FM, Petit C, Dawson SJ, Brown SD, Marcotti W, El-Amraoui A, Bowl MR, , Clarin-2 is essential for hearing by maintaining stereocilia integrity and function., EMBO Mol Med 2019 09; 11(9): e10288.
• 2019
  Defourny J, Aghaie A, Perfettini I, Avan P, Delmaghani S, Petit C, , Pejvakin-mediated pexophagy protects auditory hair cells against noise-induced damage., Proc. Natl. Acad. Sci. U.S.A. 2019 04; 116(16): 8010-8017.
• 2019
  Akil O, Dyka F, Calvet C, Emptoz A, Lahlou G, Nouaille S, Boutet de Monvel J, Hardelin JP, Hauswirth WW, Avan P, Petit C, Safieddine S, Lustig LR, , Dual AAV-mediated gene therapy restores hearing in a DFNB9 mouse model., Proc. Natl. Acad. Sci. U.S.A. 2019 03; 116(10): 4496-4501.
• 2018
  Puy V, Darwiche W, Trudel S, Gomila C, Lony C, Puy L, Lefebvre T, Vitry S, Boullier A, Karim Z, Ausseil J, , Predominant role of microglia in brain iron retention in Sanfilippo syndrome, a pediatric neurodegenerative disease., Glia 2018 08; 66(8): 1709-1723.
• 2018
  Dulon D, Papal S, Patni P, Cortese M, Vincent PF, Tertrais M, Emptoz A, Tlili A, Bouleau Y, Michel V, Delmaghani S, Aghaie A, Pepermans E, Allegria-Prevot O, Akil O, Lustig L, Avan P, Safieddine S, Petit C, El-Amraoui A, Clarin-1 gene transfer rescues auditory synaptopathy in model of Usher syndrome, J. Clin. Invest. 2018 Jul;.
• 2018
  Booth KT, Kahrizi K, Babanejad M, Daghagh H, Bademci G, Arzhangi S, Zareabdollahi D, Duman D, El-Amraoui A, Tekin M, Najmabadi H, Azaiez H, Smith RJ, Variants in CIB2 cause DFNB48 and not USH1J, Clin. Genet. 2018 Apr;93(4):812-821.
• 2018
  Trouillet A, Dubus E, Dégardin J, Estivalet A, Ivkovic I, Godefroy D, García-Ayuso D, Simonutti M, Sahly I, Sahel JA, El-Amraoui A, Petit C, Picaud S, Cone degeneration is triggered by the absence of USH1 proteins but prevented by antioxidant treatments, Sci Rep 2018 Jan;8(1):1968.
• 2017
  Michel V, Booth KT, Patni P, Cortese M, Azaiez H, Bahloul A, Kahrizi K, Labbé M, Emptoz A, Lelli A, Dégardin J, Dupont T, Aghaie A, Oficjalska-Pham D, Picaud S, Najmabadi H, Smith RJ, Bowl MR, Brown SD, Avan P, Petit C, El-Amraoui A, CIB2, defective in isolated deafness, is key for auditory hair cell mechanotransduction and survival, EMBO Mol Med 2017 Dec;9(12):1711-1731.
• 2017
  Michalski N, Goutman JD, Auclair SM, Boutet de Monvel J, Tertrais M, Emptoz A, Parrin A, Nouaille S, Guillon M, Sachse M, Ciric D, Bahloul A, Hardelin JP, Sutton RB, Avan P, Krishnakumar SS, Rothman JE, Dulon D, Safieddine S, Petit C, , Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses., Elife 2017 11; 6(): .
• 2017
  Bahloul A, Pepermans E, Raynal B, Wolff N, Cordier F, England P, Nouaille S, Baron B, El-Amraoui A, Hardelin JP, Durand D, Petit C, Conformational switch of harmonin, a submembrane scaffold protein of the hair cell mechanoelectrical transduction machinery, FEBS Lett. 2017 08;591(15):2299-2310.
• 2017
  Bossou YM, Serssar Y, Allou A, Vitry S, Momas I, Seta N, Menotti J, Achard S, , Impact of Mycotoxins Secreted by Aspergillus Molds on the Inflammatory Response of Human Corneal Epithelial Cells., Toxins (Basel) 2017 06; 9(7): .
• 2017
  Schietroma C, Parain K, Estivalet A, Aghaie A, Boutet de Monvel J, Picaud S, Sahel JA, Perron M, El-Amraoui A, Petit C, Usher syndrome type 1-associated cadherins shape the photoreceptor outer segment, J. Cell Biol. 2017 Jun;216(6):1849-1864.
• 2017
  Cortese M, Papal S, Pisciottano F, Elgoyhen AB, Hardelin JP, Petit C, Franchini LF, El-Amraoui A, Spectrin βV adaptive mutations and changes in subcellular location correlate with emergence of hair cell electromotility in mammalians, Proc. Natl. Acad. Sci. U.S.A. 2017 Feb;114(8):2054-2059.
• 2016
  El-Amraoui A, Petit C, Cadherins in the auditory sensory organ, Shintaro T. Suzuki & Shinji Hirano (eds.), In The Cadherin Superfamily, Springer, Japan. pp 341-361 (2016).
• 2016
  Potter PK, Bowl MR, Jeyarajan P, Wisby L, Blease A, Goldsworthy ME, Simon MM, Greenaway S, Michel V, Barnard A, Aguilar C, Agnew T, Banks G, Blake A, Chessum L, Dorning J, Falcone S, Goosey L, Harris S, Haynes A, Heise I, Hillier R, Hough T, Hoslin A, Hutchison M, King R, Kumar S, Lad HV, Law G, MacLaren RE, Morse S, Nicol T, Parker A, Pickford K, Sethi S, Starbuck B, Stelma F, Cheeseman M, Cross SH, Foster RG, Jackson IJ, Peirson SN, Thakker RV, Vincent T, Scudamore C, Wells S, El-Amraoui A, Petit C, Acevedo-Arozena A, Nolan PM, Cox R, Mallon AM, Brown SD, Novel gene function revealed by mouse mutagenesis screens for models of age-related disease, Nat Commun 2016 Aug;7:12444.
• 2016
  Bonnet C, Riahi Z, Chantot-Bastaraud S, Smagghe L, Letexier M, Marcaillou C, Lefèvre GM, Hardelin JP, El-Amraoui A, Singh-Estivalet A, Mohand-Saïd S, Kohl S, Kurtenbach A, Sliesoraityte I, Zobor D, Gherbi S, Testa F, Simonelli F, Banfi S, Fakin A, Glavač D, Jarc-Vidmar M, Zupan A, Battelino S, Martorell Sampol L, Claveria MA, Catala Mora J, Dad S, Møller LB, Rodriguez Jorge J, Hawlina M, Auricchio A, Sahel JA, Marlin S, Zrenner E, Audo I, Petit C, An innovative strategy for the molecular diagnosis of Usher syndrome identifies causal biallelic mutations in 93% of European patients, Eur. J. Hum. Genet. 2016 Dec;24(12):1730-1738.
• 2016
  Lelli A, Michel V, Boutet de Monvel J, Cortese M, Bosch-Grau M, Aghaie A, Perfettini I, Dupont T, Avan P, El-Amraoui A, Petit C, Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth, J. Cell Biol. 2016 Jan;212(2):231-44.
• 2015
  Baldo G, Lorenzini DM, Santos DS, Mayer FQ, Vitry S, Bigou S, Heard JM, Matte U, Giugliani R, , Shotgun proteomics reveals possible mechanisms for cognitive impairment in Mucopolysaccharidosis I mice., Mol. Genet. Metab. 2015 Feb; 114(2): 138-45.
• 2014
  Lhériteau E, Petit L, Weber M, Le Meur G, Deschamps JY, Libeau L, Mendes-Madeira A, Guihal C, François A, Guyon R, Provost N, Lemoine F, Papal S, El-Amraoui A, Colle MA, Moullier P, Rolling F, Successful gene therapy in the RPGRIP1-deficient dog: a large model of cone-rod dystrophy, Mol. Ther. 2014 Feb;22(2):265-77.
• 2014
  Kamiya K, Michel V, Giraudet F, Riederer B, Foucher I, Papal S, Perfettini I, Le Gal S, Verpy E, Xia W, Seidler U, Georgescu MM, Avan P, El-Amraoui A, Petit C, An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells, Proc. Natl. Acad. Sci. U.S.A. 2014 Jun;111(25):9307-12.
• 2014
  El-Amraoui A, Petit C, The retinal phenotype of Usher syndrome: pathophysiological insights from animal models, C. R. Biol. 2014 Mar;337(3):167-77.
• 2013
  Papal S, Cortese M, Legendre K, Sorusch N, Dragavon J, Sahly I, Shorte S, Wolfrum U, Petit C, El-Amraoui A, The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route, Hum. Mol. Genet. 2013 Sep;22(18):3773-88.
• 2013
  El-Amraoui A, Petit C, Cadherin defects in inherited human diseases, Prog Mol Biol Transl Sci 2013;116:361-84.
• 2012
  El-Amraoui A, Petit C, Gene and cell therapies to listen to the inner ear | Les thérapies génique et cellulaire à l’écoute de l’oreille interne, Biofutur, Issue 337, November 2012, Pages 40-42.
• 2012
  El-Amraoui A, Petit C, Hereditary hearing loss | Atteintes héréditaires de l’audition, Biofutur. Issue 337, November 2012, Pages 28-29.
• 2012
  Bonnet C, El-Amraoui A, Usher syndrome (sensorineural deafness and retinitis pigmentosa): pathogenesis, molecular diagnosis and therapeutic approaches, Curr. Opin. Neurol. 2012 Feb;25(1):42-9.
• 2012
  Safieddine S, El-Amraoui A, Petit C, The auditory hair cell ribbon synapse: from assembly to function, Annu. Rev. Neurosci. 2012;35:509-28.
• 2010
  Heard JM, Bruyère J, Roy E, Bigou S, Ausseil J, Vitry S, , Storage problems in lysosomal diseases., Biochem. Soc. Trans. 2010 Dec; 38(6): 1442-7.
• 2010
  El-Amraoui A, Petit C, [Stem cell therapy in the inner ear: recent achievements and prospects], Med Sci (Paris) 2010 Nov;26(11):981-5.
• 2010
  El-Amraoui A, Petit C, Cadherins as targets for genetic diseases, Cold Spring Harb Perspect Biol 2010 Jan;2(1):a003095.
• 2010
  Hocquemiller M, Vitry S, Bigou S, Bruyère J, Ausseil J, Heard JM, , GAP43 overexpression and enhanced neurite outgrowth in mucopolysaccharidosis type IIIB cortical neuron cultures., J. Neurosci. Res. 2010 Jan; 88(1): 202-13.
• 2009
  Kirian Legendre, Christine Petit et Aziz El-Amraoui*, The outer hair cell of the mammalian cochlea: An outstanding amplifier | La cellule ciliée externe de la cochlée des mammifères: Un amplificateur aux propriétés exceptionnelles, Med Sci (Paris) 2009 ; 25 : 117–120.
• 2009
  Legendre K, Petit C, El-Amraoui A, [The outer hair cell of the mammalian cochlea: an outstanding amplifier], Med Sci (Paris) 2009 Feb;25(2):117-20.
• 2008
  Aziz El-Amraoui, Amel Bahloul, Christine Petit, Myosin VII, Myosins pp 353-373.
• 2008
  Legendre K, Safieddine S, Küssel-Andermann P, Petit C, El-Amraoui A, alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells, J. Cell. Sci. 2008 Oct;121(Pt 20):3347-56.
• 2007
  Etournay R, Zwaenepoel I, Perfettini I, Legrain P, Petit C, El-Amraoui A, Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions, J. Cell. Sci. 2007 Aug;120(Pt 16):2838-50.
• 2005
  Adato A, Lefèvre G, Delprat B, Michel V, Michalski N, Chardenoux S, Weil D, El-Amraoui A, Petit C, Usherin, the defective protein in Usher syndrome type IIA, is likely to be a component of interstereocilia ankle links in the inner ear sensory cells, Hum. Mol. Genet. 2005 Dec;14(24):3921-32.
• 2005
  El-Amraoui A, Petit C, Usher I syndrome: unravelling the mechanisms that underlie the cohesion of the growing hair bundle in inner ear sensory cells, J. Cell. Sci. 2005 Oct;118(Pt 20):4593-603.
• 2005
  El-Amraoui A, Lefèvre G, Hardelin JP, Petit C, [Usher syndrome type I and the differentiation of inner ear sensory cells’ hair bundles], Med Sci (Paris) 2005 Aug-Sep;21(8-9):737-40.
• 2005
  Etournay R, El-Amraoui A, Bahloul A, Blanchard S, Roux I, Pézeron G, Michalski N, Daviet L, Hardelin JP, Legrain P, Petit C, PHR1, an integral membrane protein of the inner ear sensory cells, directly interacts with myosin 1c and myosin VIIa, J. Cell. Sci. 2005 Jul;118(Pt 13):2891-9.
• 2004
  Adato A, Michel V, Kikkawa Y, Reiners J, Alagramam KN, Weil D, Yonekawa H, Wolfrum U, El-Amraoui A, Petit C, Interactions in the network of Usher syndrome type 1 proteins, Hum. Mol. Genet. 2005 Feb;14(3):347-56.
• 2004
  Delprat B, Michel V, Goodyear R, Yamasaki Y, Michalski N, El-Amraoui A, Perfettini I, Legrain P, Richardson G, Hardelin JP, Petit C, Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly, Hum. Mol. Genet. 2005 Feb;14(3):401-10.
• 2004
  Sousa S, Cabanes D, El-Amraoui A, Petit C, Lecuit M, Cossart P, , Unconventional myosin VIIa and vezatin, two proteins crucial for Listeria entry into epithelial cells., J Cell Sci 2004 Apr; 117(Pt 10): 2121-30.
• 2003
  Weil D, El-Amraoui A, Masmoudi S, Mustapha M, Kikkawa Y, Lainé S, Delmaghani S, Adato A, Nadifi S, Zina ZB, Hamel C, Gal A, Ayadi H, Yonekawa H, Petit C, Usher syndrome type I G (USH1G) is caused by mutations in the gene encoding SANS, a protein that associates with the USH1C protein, harmonin, Hum. Mol. Genet. 2003 Mar;12(5):463-71.
• 2002
  El-Amraoui A, Schonn JS, Küssel-Andermann P, Blanchard S, Desnos C, Henry JP, Wolfrum U, Darchen F, Petit C, MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes, EMBO Rep. 2002 May;3(5):463-70.
• 2001
  El-Amraoui A, Cohen-Salmon M, Petit C, Simmler MC, Spatiotemporal expression of otogelin in the developing and adult mouse inner ear, Hear. Res. 2001 Aug;158(1-2):151-9.
• 2000
  Küssel-Andermann P, El-Amraoui A, Safieddine S, Nouaille S, Perfettini I, Lecuit M, Cossart P, Wolfrum U, Petit C, , Vezatin, a novel transmembrane protein, bridges myosin VIIA to the cadherin-catenins complex., EMBO J 2000 Nov; 19(22): 6020-9.
• 2000
  Küssel-Andermann P, El-Amraoui A, Safieddine S, Hardelin JP, Nouaille S, Camonis J, Petit C, Unconventional myosin VIIA is a novel A-kinase-anchoring protein, J. Biol. Chem. 2000 Sep;275(38):29654-9.
• 2000
  Kharkovets T, Hardelin JP, Safieddine S, Schweizer M, El-Amraoui A, Petit C, Jentsch TJ, KCNQ4, a K+ channel mutated in a form of dominant deafness, is expressed in the inner ear and the central auditory pathway, Proc. Natl. Acad. Sci. U.S.A. 2000 Apr;97(8):4333-8.
• 2000
  Simmler MC, Cohen-Salmon M, El-Amraoui A, Guillaud L, Benichou JC, Petit C, Panthier JJ, Targeted disruption of otog results in deafness and severe imbalance, Nat. Genet. 2000 Feb;24(2):139-43.
• 1999
  Yasunaga S, Grati M, Cohen-Salmon M, El-Amraoui A, Mustapha M, Salem N, El-Zir E, Loiselet J, Petit C, A mutation in OTOF, encoding otoferlin, a FER-1-like protein, causes DFNB9, a nonsyndromic form of deafness, Nat. Genet. 1999 Apr;21(4):363-9.
• 1999
  Kubisch C, Schroeder BC, Friedrich T, Lütjohann B, El-Amraoui A, Marlin S, Petit C, Jentsch TJ, KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness, Cell 1999 Feb;96(3):437-46.
• 1998
  Kalatzis V, Sahly I, El-Amraoui A, Petit C, Eya1 expression in the developing ear and kidney: towards the understanding of the pathogenesis of Branchio-Oto-Renal (BOR) syndrome, Dev. Dyn. 1998 Dec;213(4):486-99.
• 1997
  Cohen-Salmon M, El-Amraoui A, Leibovici M, Petit C, Otogelin: a glycoprotein specific to the acellular membranes of the inner ear, Proc. Natl. Acad. Sci. U.S.A. 1997 Dec;94(26):14450-5.
• 1997
  El-Amraoui A, Petit C, Towards a molecular understanding of the pathophysiology of Usher syndrome, Journal of Audiological MedicineVolume 6, Issue 3, 1997, Pages 170-184.
• 1997
  Dubois PM, el Amraoui A, Héritier AG, Development and differentiation of pituitary cells, Microsc. Res. Tech. 1997 Oct;39(2):98-113.
• 1997
  Sahly I, El-Amraoui A, Abitbol M, Petit C, Dufier JL, Expression of myosin VIIA during mouse embryogenesis, Anat. Embryol. 1997 Aug;196(2):159-70.
• 1997
  Crozet F, el Amraoui A, Blanchard S, Lenoir M, Ripoll C, Vago P, Hamel C, Fizames C, Levi-Acobas F, Depétris D, Mattei MG, Weil D, Pujol R, Petit C, Cloning of the genes encoding two murine and human cochlear unconventional type I myosins, Genomics 1997 Mar;40(2):332-41.
• 1996
  Verney C, el Amraoui A, Zecevic N, Comigration of tyrosine hydroxylase- and gonadotropin-releasing hormone-immunoreactive neurons in the nasal area of human embryos, Brain Res. Dev. Brain Res. 1996 Dec;97(2):251-9.
• 1996
  el-Amraoui A, Sahly I, Picaud S, Sahel J, Abitbol M, Petit C, Human Usher 1B/mouse shaker-1: the retinal phenotype discrepancy explained by the presence/absence of myosin VIIA in the photoreceptor cells, Hum. Mol. Genet. 1996 Aug;5(8):1171-8.
• 1996
  Weil D, Levy G, Sahly I, Levi-Acobas F, Blanchard S, El-Amraoui A, Crozet F, Philippe H, Abitbol M, Petit C, Human myosin VIIA responsible for the Usher 1B syndrome: a predicted membrane-associated motor protein expressed in developing sensory epithelia, Proc. Natl. Acad. Sci. U.S.A. 1996 Apr;93(8):3232-7.
• 1995
  Elamraoui A, Berghman LR, Dubois PM, Interactions between adenohypophyseal, hypothalamic and nasal presumptive territories during early neurulation process, Endocrine 1995 May;3(5):335-43.
• 1993
  elAmraoui A, Dubois PM, Experimental evidence for the early commitment of the presumptive adenohypophysis, Neuroendocrinology 1993 Dec;58(6):609-15.
• 1993
  el Amraoui A, Dubois PM, Experimental evidence for an early commitment of gonadotropin-releasing hormone neurons, with special regard to their origin from the ectoderm of nasal cavity presumptive territory, Neuroendocrinology 1993 Jun;57(6):991-1002.