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Deputy Director of Department
Deputy Director of National Reference Center
Deputy Head of Facility
Director of Center
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Director of Institute
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Honorary President of the Departement
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Studying vulnerability to drug addiction: contribution of the nicotinic acetylcholine receptor α5 subunit.

Discovery of allosteric modulators specifically targeting α5-containing nAChRs. (ANR-Nicofive)

© Pierre Lafaye

Astrocytes marqués par des anticorps VHH anti-GFAP. Des anticorps d'alpagas dirigés contre une protéine spécifique des astrocytes, la GFAP (Glial Fibrillary Acidic Protein), ont été obtenus à partir de camélidés immunisés. La partie VHH (partie de l'anticorps qui reconnaît l'antigène) a été exprimée sous forme recombinante chez Escherichia coli.

Project

Toxins and VHHs as subtype-specific ligands and allosteric modulators of nicotinic acetylcholine receptors (PTR Nicobinder)

Team: Antibody Engineering

Team: Integrative Neurobiology of Cholinergic Systems

Team: Signaling and receptors dynamics

Network: Institut Pasteur de Tunis

Department of: Neuroscience

Department of: Structural Biology and Chemistry

Project leader: Pierre-Jean Corringer

Member: Uwe Maskos

Member: Pierre Lafaye

Member: Gabriel Aymé

Scientific Fields

Diseases

Organisms

Applications

Technique

Starting Date

01

Jan 2018

Ending Date

01

Jan 2021

Status

Ongoing

Members

4

Structures

6

Instituts

1

About

Fundings

Published on: 27 Feb 2018 • Modified on: 12 Nov 2024