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  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Full Professor
  • Graduate Student
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
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Scientific Fields
Diseases
Organisms
Applications
Technique
Starting Date
01
Oct 2015
Ending Date
30
Sep 2019
Status
Ongoing
Members
2
Structures
2

About

Understanding the molecular basis of host-pathogen interactions is critical for the discovery of new therapeutic approaches to treat infectious diseases, which in the face of increasing antibiotic resistance and emerging pathogens, is a major priority medical research in Europe. Studying the signalling pathways in immune cells during infection also gives us fundamental information about the mechanisms of immune cell activation during inflammation that is relevant for other human diseases including autoimmune disease, cardiovascular disease and even cancer. With this grant we focus on the process of components of the macroautophagy machinery within macrophages that are infected with bacterial pathogens, and we put it into relation with innate immune signaling. At the Institut Pasteur, we are collaborating with the team of Robert Weil on this project. It is coordinated by Toby Lawrence at the CIML in Marseille.

Fundings