New publication – Tumor-intrinsic sensitivity to the pro-apoptotic effects of IFN-γ is a major determinant of CD4+ CAR T-cell antitumor activity

Source

Tumor-intrinsic sensitivity to the pro-apoptotic effects of IFN-γ is a major determinant of CD4+ CAR T-cell antitumor activity, Nature Cancer, 29 mai 2023

Attack of a tumor by CAR T cells visualised using intravital imaging. Living cancer cells are shown in white, killed cancer cells in blue and CAR T cells in green. The white circles indicate the destruction of cancer cells during direct contact with CAR T cells, while the red circles indicate the destruction of cancer cells at a distance. © Morgane Boulch, Philippe Bousso / Institut Pasteur

Read the press release: Immunothérapies des cancers du sang : mise en évidence de la destruction à distance des cellules cancéreuses