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Role of human polymorphisms in nicotinic receptors in lung cancer and COPD
Stéphanie Pons (PI)
Lung diseases are also a major public health problem. Chronic obstructive pulmonary disease (COPD) will be the third cause of mortality worldwide in 2020 and lung cancer is the leading cause of cancer-related mortality […]
2016Nicotinic receptors in the ventral tegmental area promote uncertainty-seeking, Nat. Neurosci. 2016 Jan;.
2013Nicotine consumption is regulated by a human polymorphism in dopamine neurons, Mol. Psychiatry 2014 Aug;19(8):930-6.
2013Contribution of α7 nicotinic receptor to airway epithelium dysfunction under nicotine exposure, Proc. Natl. Acad. Sci. U.S.A. 2013 Mar;110(10):4099-104.
2012Co-activation of VTA DA and GABA neurons mediates nicotine reinforcement, Mol. Psychiatry 2013 Mar;18(3):382-93.
2012Selective re-expression of β2 nicotinic acetylcholine receptor subunits in the ventral tegmental area of the mouse restores intravenous nicotine self-administration, Neuropharmacology 2012 Aug;63(2):235-41.
2011Modulation of the mouse prefrontal cortex activation by neuronal nicotinic receptors during novelty exploration but not by exploration of a familiar environment, Cereb. Cortex 2012 May;22(5):1007-15.
2011Aversion to nicotine is regulated by the balanced activity of β4 and α5 nicotinic receptor subunits in the medial habenula, Neuron 2011 May;70(3):522-35.
2011Distinct contributions of nicotinic acetylcholine receptor subunit alpha4 and subunit alpha6 to the reinforcing effects of nicotine, Proc. Natl. Acad. Sci. U.S.A. 2011 May;108(18):7577-82.
2011Prefrontal nicotinic receptors control novel social interaction between mice, FASEB J. 2011 Jul;25(7):2145-55.
2009Effect of the alpha4beta2* nicotinic acetylcholine receptor partial agonist varenicline on dopamine release in beta2 knock-out mice with selective re-expression of the beta2 subunit in the ventral tegmental area, Neuropharmacology 2010 Feb;58(2):346-50.
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